Abstract: A robot for imaging and excision of two-dimensional fluorescent gels. An array detector is mounted in the roof of the robot to image down onto a gel dish placed on a light table. Fluorescence is excited by illuminating the light table from below with light emitting diodes mounted under the main bed of the apparatus. It is therefore possible to perform gel fluorescence analysis and coring (excision) using the same machine. The integration is based on a transmission mode optical design, distinct from prior art scanners and imagers which are based on reflection mode designs. This approach allows the conventional layout of a microarraying or picking robot to be maintained, avoiding unnecessary redesign of other robot functions associated with well plate and container handling. The apparatus may also be used for contrast imaging of non-fluorescent gels.

Abstract: A robot for imaging and excision of two-dimensional fluorescent gels. An array detector is mounted in the roof of the robot to image down onto a gel dish placed on a light table. Fluorescence is excited by illuminating the light table from below with light emitting diodes mounted under the main bed of the apparatus. It is therefore possible to perform gel fluorescence analysis and coring (excision) using the same machine. The integration is based on a transmission mode optical design, distinct from prior art scanners and imagers which are based on reflection mode designs. This approach allows the conventional layout of a microarraying or picking robot to be maintained, avoiding unnecessary redesign of other robot functions associated with well plate and container handling. The apparatus may also be used for contrast imaging of non-fluorescent gels.