Abstract: An endoprosthesis for deployment within a body passage includes a framework and a metallic film, which can circumferentially surround the framework or be surrounded by the framework. The framework and metallic film can be attached without using a third material, e.g., without sewing. The framework can define a circumferential recess along at least a portion of its length and circumference. The recess accommodates at least a portion of the metallic film therein.

Abstract: An endoprosthesis for deployment within a body passage includes a framework and a metallic film, which can circumferentially surround the framework or be surrounded by the framework. The framework and metallic film can be attached without using a third material, e.g., without sewing. The framework can define a circumferential recess along at least a portion of its length and circumference. The recess accommodates at least a portion of the metallic film therein.

Abstract: Medical devices, such as endoprostheses, and methods of making the devices are disclosed. The medical device can include a stent body and a cover including a deposited metallic film. The medical device can be delivered using a delivery device along a tortuous body passage to a treatment site without damaging the medical device, delivery device, or the body passage. In some cases, the stent body is a flexible helical stent body, which may be threaded through one or more fenestrations of the cover. The cover may include longitudinally extending slits or seams, which help the cover to pass through small radii passages without buckling.

Abstract: A method of measuring blood pressure and velocity proximally and distally of a stenosis in a vessel carrying blood includes the steps of providing a guide wire having both a pressure sensor and a velocity sensor disposed on a distal region of the guide wire, introducing the guide wire into the vessel, advancing the guide wire to position the pressure sensor and the velocity sensor proximally and distally of the stenosis, and measuring the blood pressure and velocity proximally and distally of the stenosis with the pressure sensor and the velocity sensor.

Abstract: Medical devices, such as endoprostheses, and methods of making the devices are disclosed. The medical device can include a composite cover formed of a deposited metallic film and one or more polymer layers. The polymer layers contribute to mechanical or biological properties of the endoprosthesis.

Abstract: A method of measuring blood pressure and velocity proximally and distally of a stenosis in a vessel carrying blood includes the steps of providing a guide wire having both a pressure sensor and a velocity sensor disposed on a distal region of the guide wire, introducing the guide wire into the vessel, advancing the guide wire to position the pressure sensor and the velocity sensor proximally and distally of the stenosis, and measuring the blood pressure and velocity proximally and distally of the stenosis with the pressure sensor and the velocity sensor.

Abstract: Hypotubes such as micromachined hypotubes can include one or more tie layers appropriate for subsequent application of a hydrophilic coating. In particular, a medical device may include a micromachined hypotube having a level of flexibility and a tie layer disposed over the hypotube such that the medical device has a level of flexibility at least substantially equivalent to the level of flexibility of the hypotube.

Abstract: A method of measuring blood pressure and velocity proximally and distally of a stenosis in a vessel carrying blood includes the steps of providing a guide wire having both a pressure sensor and a velocity sensor disposed on a distal region of the guide wire, introducing the guide wire into the vessel, advancing the guide wire to position the pressure sensor and the velocity sensor proximally and distally of the stenosis, and measuring the blood pressure and velocity proximally and distally of the stenosis with the pressure sensor and the velocity sensor.

Abstract: Medical devices, such as endoprostheses, and methods of making the devices are disclosed. The medical device can include a composite cover formed of a deposited metallic film and one or more polymer layers. The polymer layers contribute to mechanical or biological properties of the endoprosthesis.

Abstract: Medical devices, such as endoprostheses, and methods of making the devices are disclosed. The medical device can include a composite cover formed of a deposited metallic film and one or more polymer layers. The polymer layers contribute to mechanical or biological properties of the endoprosthesis.

Abstract: A bifurcated stent comprises a body portion, a first branch portion, a second branch portion, a first pivot portion and a second pivot portion constructed from a common continuous sheet of stent material. The body portion, first branch portion and second branch portion provided with a substantially tubular shape, the tubular shape of each defines a lumen respectively therethrough. The lumen defined by the body portion is in fluid communication with the lumen defined by the first branch portion and the second branch portion. The first branch portion is pivotally engaged to an end of the body portion by the first pivot portion. The second branch portion is pivotally engaged to an end of the body portion by the second pivot portion.

Abstract: A guide wire having pressure sensing capabilities for measuring the pressure of liquid in a vessel comprising a flexible elongate member and having proximal and distal extremities and having an outside diameter of 0.018? or less. The distal extremity of said flexible elongate member is adapted to be disposed in the liquid in said vessel. A housing is carried by the flexible elongate member and has a diameter substantially the same as the diameter of the flexible elongate member. The housing has a space therein with a pressure sensor mounted in the space in the housing. The pressure sensor has a diaphragm that is sensitive to changes of pressure in the liquid in the vessel. The diaphragm is rectangular in shape and is bordered by a rim surrounding the well. A backing plate is formed of an insulating material bonded to the crystal and serves to reinforce the rim of the crystal of semiconductor material.

Abstract: A guide wire having pressure sensing capabilities for measuring the pressure of liquid in a vessel comprising a flexible elongate member and having proximal and distal extremities and having an outside diameter of 0.018? or less. The distal extremity of said flexible elongate member is adapted to be disposed in the liquid in said vessel. A housing is carried by the flexible elongate member and has a diameter substantially the same as the diameter of the flexible elongate member. The housing has a space therein with a pressure sensor mounted in the space in the housing. The pressure sensor has a diaphragm that is sensitive to changes of pressure in the liquid in the vessel. The diaphragm is rectangular in shape and is bordered by a rim surrounding the well. A backing plate is formed of an insulating material bonded to the crystal and serves to reinforce the rim of the crystal of semiconductor material.

Abstract: A method of measuring blood pressure and velocity proximally and distally of a stenosis in a vessel carrying blood includes the steps of providing a guide wire having both a pressure sensor and a velocity sensor disposed on a distal region of the guide wire, introducing the guide wire into the vessel, advancing the guide wire to position the pressure sensor and the velocity sensor proximally and distally of the stenosis, and measuring the blood pressure and velocity proximally and distally of the stenosis with the pressure sensor and the velocity sensor.

Abstract: A bifurcated stent comprises a body portion, a first branch portion, a second branch portion, a first pivot portion and a second pivot portion constructed from a common continuous sheet of stent material. The body portion, first branch portion and second branch portion provided with a substantially tubular shape, the tubular shape of each defines a lumen respectively therethrough. The lumen defined by the body portion is in fluid communication with the lumen defined by the first branch portion and the second branch portion. The first branch portion is pivotally engaged to an end of the body portion by the first pivot portion. The second branch portion is pivotally engaged to an end of the body portion by the second pivot portion.

Abstract: A guide wire having pressure sensing capabilities for measuring the pressure of liquid in a vessel comprising a flexible elongate member and having proximal and distal extremities and having an outside diameter of 0.018″ or less. The distal extremity of said flexible elongate member is adapted to be disposed in the liquid in said vessel. A housing is carried by the flexible elongate member and has a diameter substantially the same as the diameter of the flexible elongate member. The housing has a space therein with a pressure sensor mounted in the space in the housing. The pressure sensor has a diaphragm that is sensitive to changes of pressure in the liquid in the vessel. The diaphragm is rectangular in shape and is bordered by a rim surrounding the well. A backing plate is formed of an insulating material bonded to the crystal and serves to reinforce the rim of the crystal of semiconductor material.

Abstract: A guide wire having pressure sensing capabilities for measuring the pressure of liquid in a vessel comprising a flexible elongate member and having proximal and distal extremities and having an outside diameter of 0.018″ or less. The distal extremity of said flexible elongate member is adapted to be disposed in the liquid in said vessel. A housing is carried by the flexible elongate member and has a diameter substantially the same as the diameter of the flexible elongate member. The housing has a space therein with a pressure sensor mounted in the space in the housing. The pressure sensor has a diaphragm that is sensitive to changes of pressure in the liquid in the vessel. The diaphragm is rectangular in shape and is bordered by a rim surrounding the well. A backing plate is formed of an insulating material bonded to the crystal and serves to reinforce the rim of the crystal of semiconductor material.

Abstract: A guide wire having pressure sensing capabilities for measuring the pressure of liquid in a vessel comprising a flexible elongate member and having proximal and distal extremities and having an outside diameter of 0.018" or less. The distal extremity of said flexible elongate member is adapted to be disposed in the liquid in said vessel. A housing is carried by the flexible elongate member and has a diameter substantially the same as the diameter of the flexible elongate member. The housing has a space therein with a pressure sensor mounted in the space in the housing. The pressure sensor has a diaphragm that is sensitive to changes of pressure in the liquid in the vessel. The diaphragm is rectangular in shape and is bordered by a rim surrounding the well. A backing plate is formed of an insulating material bonded to the crystal and serves to reinforce the rim of the crystal of semiconductor material.

Abstract: A guidewire having pressure sensing capabilities for measuring the pressure of liquid in a vessel comprising a flexible elongate member and having proximal and distal extremities and having an outside diameter of 0.018" or less. The distal extremity of said flexible elongate member is adapted to be disposed in the liquid in said vessel. A housing is carried by the flexible elongate member and has a diameter substantially the same as the diameter of the flexible elongate member. The housing has a space therein with a pressure sensor mounted in the space in the housing. The pressure sensor has a diaphragm that is sensitive to changes of pressure in the liquid in the vessel. The diaphragm is rectangular in shape and is bordered by a rim surrounding the well. A backing plate is formed of an insulating material bonded to the crystal and serves to reinforce the rim of the crystal of semiconductor material.

Abstract: Rotary connector for use with a flexible elongate member having electrical properties and having a proximal extremity with at least first and second conductive spaced-apart sleeves provided thereon. A housing is provided having a bore therein. First and second spaced-apart conductive disks are disposed in said bore. The disks are adapted to have the proximal extremity of the flexible elongate member extend therethrough and to have the conductive sleeves be in contact with the conductive disks while permitting rotation of the flexible elongate member, a push button clamping assembly is carried by the housing for retaining the proximal extremity of the flexible elongate member in the housing. Leads are connected to the conductive disks.