Patents by Inventor Robert Ziegelmaier

Robert Ziegelmaier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • One-step immunoassay for the determination of antigen-specific antibodies of one of the immunoglobulin classes A, M, D, or E, and an agent suitable for this purpose
    Patent number: 6632682
    Abstract: An immunochemical method for the determination of antibodies which are specific for an antigen and are of one of the immunoglobulin classes: A, M, D or E in a fluid, with this fluid being contacted with a solid phase to which the antibodies against this immunoglobulin class, or a fragment of an antibody of this type, are bound, which results in the immunoglobulin of this class being bound to this solid phase, and this solid phase being contacted with the antigen, which carries a labeling means where appropriate, and with a labeled antibody or a labeled fragment of an antibody against the antigen if the antigen is unlabeled and determination, from the amount of labeling means which is bound to the solid phase, of the amount of these antibodies which are specific for an antigen and are one of the immunoglobulin classes, which comprises the solid phase being simultaneously in contact with the fluid containing the antibody which is to be determined and with the antigen, which is labeled where appropriate, there b
    Type: Grant
    Filed: May 22, 1995
    Date of Patent: October 14, 2003
    Assignee: Dade Behring Marburg GmbH
    Inventor: Robert Ziegelmaier
  • Toxoplasma gondii antigens, the preparation thereof and the use thereof
    Patent number: 6419925
    Abstract: The present invention relates to the identification of toxoplasma gondii antigens and the preparation thereof by genetic engineering. A cDNA expression gene bank of this parasite was prepared. Recombinant clones which are of diagnostic interest were identified using a high-titer rabbit anti-Toxoplasma gondii serum, and isolated.
    Type: Grant
    Filed: October 3, 2001
    Date of Patent: July 16, 2002
    Assignee: Dade Behring Marburg GmbH
    Inventors: Stefan Knapp, Robert Ziegelmaier, Hans Küpper
  • Toxoplasma gondii antigens, the preparation thereof and the use thereof
    Patent number: 6326008
    Abstract: The present invention relates to the identification of toxoplasma gondii antigens and the preparation thereof by genetic engineering. A cDNA expression gene bank of this parasite was prepared. Recombinant clones which are of diagnostic interest were identified using a high-titer rabbit anti-Toxoplasma gondii serum, and isolated.
    Type: Grant
    Filed: December 16, 1999
    Date of Patent: December 4, 2001
    Assignee: Dade Behring Marburg GmbH
    Inventors: Stefan Knapp, Robert Ziegelmaier, Hans Küpper
  • HCMV-specific peptides, agents therefor and the use thereof
    Patent number: 6143493
    Abstract: The invention relates to peptides for the immunochemical determination of human cytomegalovirus (HCMV)-specific antibodies and HCMV antigens, and to agents suitable for this method and to the use thereof.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: November 7, 2000
    Assignee: Dade Behring Marburg GmbH
    Inventors: Werner Stuber, Leszek Wieczorek, Robert Ziegelmaier
  • Toxoplasma gondii antigens, the preparation thereof and the use thereof
    Patent number: 6022546
    Abstract: The present invention relates to the identification of Toxoplasma gondii antigens and the preparation thereof by genetic engineering. A cDNA expression gene bank of this parasite was prepared. Recombinant clones which are of diagnostic interest were identified using a high-titer rabbit anti-Toxoplasma gondii serum, and isolated.
    Type: Grant
    Filed: September 6, 1994
    Date of Patent: February 8, 2000
    Assignee: Dade Behring Marburg GmbH
    Inventors: Stefan Knapp, Robert Ziegelmaier, Hans Kupper
  • HCMV-specific peptides, agents therefor and the use thereof
    Patent number: 5859185
    Abstract: The invention relates to peptides for the immunochemical determination of human cytomegalovirus (HCMV)-specific antibodies and HCMV antigens, and to agents suitable for this method and to the use thereof.
    Type: Grant
    Filed: February 13, 1995
    Date of Patent: January 12, 1999
    Assignee: Behringwerke Aktiengesellschaft
    Inventors: Werner Stuber, Leszek Wieczorek, Robert Ziegelmaier
  • DNA sequences which encode immunoreactive HCMV-specific peptides
    Patent number: 5744298
    Abstract: The invention relates to a DNA sequence which encodes three specific human cytomegalovirus (HCMV) peptides of the pp150 protein. These peptides are shown to have novel immunogenic properties. The DNA sequence is also used in a method of hybridization for the detection of fully complementary sequences.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: April 28, 1998
    Assignee: Behringwerke Aktiengesellschaft
    Inventors: Werner Stuber, Leszek Wieczorek, Robert Ziegelmaier