Abstract: Methods of and systems for optimizing data storage and processing in a connected vehicle system are provided. For example, the method can include receiving encoded vehicle messages from one or more transmission units and storing each of the encoded vehicle messages. The method can further include decode the stored encoded messages to produce decoded vehicle messages, analyze each of the decoded vehicle messages to identify one or more deduplicated and unique messages, and storing each of the one or more deduplicated and unique messages. The method can further include performing further processing on the one or more deduplicated and unique messages based upon a user request to generate at least one user-requested output. The system can include one or more computing components such as a computer readable medium and at least one processor for implementing the above method.

Abstract: A breathing filter assembly for filtering breathing air includes a breathing unit that includes a mouthpiece that can be placed in a user's mouth. The breathing unit includes a pair of nose tubes that can each be positioned in a respective one of the user's nostrils when the mouthpiece is positioned in the user's mouth. A filter is removably insertable into the breathing unit. The filter is made of an air permeable material to pass air therethrough for breathing. The filter extends into the mouthpiece and each of the nose tubes to filter air inhaled through the user's mouth or the user's nose.

Abstract: A breathing filter assembly for filtering breathing air includes a breathing unit that includes a mouthpiece that can be placed in a user's mouth. The breathing unit includes a pair of nose tubes that can each be positioned in a respective one of the user's nostrils when the mouthpiece is positioned in the user's mouth. A filter is removably insertable into the breathing unit. The filter is comprised of an air permeable material to pass air therethrough for breathing. The filter extends into the mouthpiece and each of the nose tubes to filter air inhaled through the user's mouth or the user's nose.

Abstract: The present invention relates to a composition comprising a Nucant multivalent synthetic compound and a glycosaminoglycan, the admixture of both compounds forming microspheres comprising both compounds, as well as their use for the treatment or prevention of diseases associated with deregulation of proliferation and/or angiogenesis, such as cancer, inflammatory disease, or for promoting wound healing.

Abstract: The present description provides compositions and methods for producing therapeutic oligomeric compounds. In another aspect the description provides methods for administering the oligomeric compounds for the treatment and prevention of disease in a mammal. In particular, the invention relates to medicaments comprising various novel oligomeric compounds and pharmaceutically acceptable salts thereof. The compounds of the invention may optionally be administered with at least one of a pharmaceutically acceptable excipient, additional pharmacologically active agent or a combination thereof.

Abstract: The present invention relates to a composition comprising a Nucant multivalent synthetic compound and a glycosaminoglycan, the admixture of both compounds forming microspheres comprising both compounds, as well as their use for the treatment or prevention of diseases associated with deregulation of proliferation and/or angiogenesis, such as cancer, inflammatory disease, or for promoting wound healing.

Abstract: The present invention relates to new optically pure compounds displaying an improved anticancer activity compared to previously known complex mixtures of stereoisomers thereof. Such compounds are of formula (I): wherein each X independently represents any amino acid; n is 0 or 1; m is an integer between 0 and 3; k is an integer of at least 3; Psi is a reduced bond of formula replacing the peptide amide bond between Lys and Pro; and wherein Lys residues in pseudopeptide units of said compound of formula (I) are either all in L configuration or all in D configuration. A method for preparing such compounds, and therapeutic uses thereof are also provided. The synthetic method involves the selective reduction of the peptide bond between Lys and Pro in a dipeptide intermediate with borane. The therapeutic uses are against cancer, inflammation and for wound healing.

Abstract: Techniques for displaying a graphical user interface operable to receive user input specifying payments to be made are described. Each payment identifies a payee and a payment method to be used to make the payment. The techniques include making a determination as to whether any of the specified payments involve a payment method that uses a third-party on-line payment system. In response to a determination that a specified payment involves a payment method that uses a third-party on-line payment system, a message is sent to the third-party on-line payment system. The message includes payment information for specified payments to be paid by the third-party on-line payment system such that the third-party on-line payment system is able to process the specified payments.

Abstract: The present invention relates to compositions and methods for producing therapeutic oligomeric compounds. In one aspect the invention relates to methods for administering the oligomeric compounds for the treatment and prevention of disease, for example, a fungal infection, bacterial infection, or cancer, in a mammal. In particular, the invention relates to medicaments comprising various novel oligomeric compounds and pharmaceutically acceptable salts thereof. The compounds of the invention may optionally be administered with at least one of a pharmaceutically acceptable excipient, pharmacologically active agent or a combination thereof.

Abstract: An apparatus for minimizing parasitic capacitance on a semiconductor die includes a semiconductor die having a least one signal line and at least one plane and an anti pad located between the at least one signal line and the at least one plane.

Abstract: Techniques for displaying a graphical user interface operable to receive user input specifying a payment to be made to a payee and a payment method to be used to make the payment are described. The payment method is one of multiple ways of making the payment using the graphical user interface. The techniques include making a determination as to whether the specified payment method involves a third-party on-line payment system. In response to a determination that the specified payment method involves a third-party on-line payment system, a message is provided to the third-party on-line payment system. The message includes payment information such that the third-party on-line payment system is able to process the payment to pay the payee. In response to a determination that the specified payment method involves a payment system other than a third-party on-line payment system, the specified method to pay the payee is initiated.

Abstract: Techniques for displaying a graphical user interface operable to receive user input specifying payments to be made are described. Each payment identifies a payee and a payment method to be used to make the payment. The techniques include making a determination as to whether any of the specified payments involve a payment method that uses a third-party on-line payment system. In response to a determination that a specified payment involves a payment method that uses a third-party on-line payment system, a message is sent to the third-party on-line payment system. The message includes payment information for specified payments to be paid by the third-party on-line payment system such that the third-party on-line payment system is able to process the specified payments.

Abstract: The present invention relates to compositions and methods for producing therapeutic oligomeric compounds. In one aspect the invention relates to methods for administering the oligomeric compounds for the treatment and prevention of disease, for example, a fungal infection, bacterial infection, or cancer, in a mammal. In particular, the invention relates to medicaments comprising various novel oligomeric compounds and pharmaceutically acceptable salts thereof. The compounds of the invention may optionally be administered with at least one of a pharmaceutically acceptable excipient, pharmacologically active agent or a combination thereof.

Abstract: A method and apparatus is presented for performing simulation of complex circuits. A circuit is simulated in a fast simulator. State information, which is the output of the fast simulator, is translated in a translator and then the circuit is simulated in a slow simulator. In one embodiment, the circuit is modeled in a digital format in the fast simulator and modeled in an analog format in the slow simulator.

Abstract: It is described a new method for the preparation of pharmaceutical tablets carrying poorly soluble in water principle; this method allows to obtain tablets with fast and/or slow release of the active principle. The peculiar feature is the fact that the poorly soluble in water active principle (es: nifedipine) is treated with a surfactant, during the granulation phase or whatever during the preparation process; the obtained product, subjected to a compression, produces pharmaceutical tablets which show high bioavailability of the carried active principle. This procedure can be used to prepare polymeric matrixes (with modified release), formed by tablets with one or more layers. The procedure of manufacture and the characteristics of the new finished tablet are described.

Abstract: Described herein is a particular type of pharmaceutical tablet, for oral use, which is formed by one or more layers, and is specifically designed for controlled release of active principles that present problems of bio-availability linked to absorption in the gastro-intestinal tract, and in particular active principles that present an erratic and unpredictable absorption linked to the presence or absence of food at the level of the stomach and/or of the first portion of the small intestine, the said pharmaceutical form being characterized in that it is completely coated with one or more films of a biocompatible and biodegradable polymeric material.

Abstract: An analog, fully integrated, partial response maximum likelihood (PRML) read channel utilizing a high-performance analog delay line, an analog adaptive equalizer and an analog Viterbi detector is provided, resulting in saved space, performance gains, and lower power consumption. For signal detection and reconstruction used in read operations, the partial response maximum likelihood (PRML) read channel includes a variable gain amplifier coupled to a lowpass filter for input to an adaptive analog equalizer. The adaptive analog equalizer comprises an analog delay line and an analog feedforward equalizer (FFE). An analog Viterbi detector employs maximum-likelihood sequence estimation (MLSE) techniques to performs the signal detection function. A decoder/descrambler produces a final reconstructed signal. The analog implementation of a partial response maximum likelihood (PRML) read channel also includes a scrambler/encoder coupled to a write precompensation circuit for output to a separate write head.

Abstract: A circuit provides a high impedance input to an operational amplifier by substituting a p-channel field effect transistor for the bias resistor normally used on the input to an operation amplifier. By placing a PFET in place of the bias resistor, a resistance value can be created that is hundreds of times higher, for the same area of silicon within the integrated circuit, as that created with an actual resistor. This PFET has parasitic capacitance which may be significantly offset by connecting the gate of the PFET to the output of a source follower circuit having its input connected to the inverting input of the operational amplifier. The circuit may be still further improved by using a voltage follower amplifier circuit in place of the source follower.

Abstract: A nonlinear noninverting amplifier design for receiving and amplifying an input signal in an optical communication scheme having a nonlinear inverting feedback is disclosed. The inverting feedback varies nonlinearly with the input signal to avoid saturation of the amplifier while providing a zero state input amplitude signal to reduce the amplitude of the input signal required to turn-on the feedback, thus allowing the amplifier to operate with a wide variation of optical generators, paths, and converters. A nonlinear noninverting amplifier design is provided which eliminates the need for automatic gain control circuitry and can be designed as an integrated circuit.

Abstract: Apparatus for attaching a floating tension leg platform to an anchoring base template on the subsea floor. The apparatus includes an external mooring porch for each tendon, the porches being mounted on the outside surfaces of the platform's columns.