Patents by Inventor Roberta Bosotti

Roberta Bosotti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human homologue of the DBF4/ASK1 protein, nucleic acids, and methods related to the same
    Patent number: 7259244
    Abstract: The present invention provides a human polypeptide homolog of DBF4/ASK1 (for “Activator of S phase kinase”) and polynucleotides which identify and encode DRF1 (for “DBF4 Related Factor 1”). In addition, the invention provides expression vectors, host cells and methods for its production. The invention also provides methods for the identification of DRF1 or DRF1-containing complex agonists/antagonists, useful for the treatment of human diseases and conditions.
    Type: Grant
    Filed: June 15, 2001
    Date of Patent: August 21, 2007
    Assignee: Nerviano Medical Sciences S.R.L.
    Inventors: Jens Berthelsen, Roberta Bosotti, Antonella Isacchi, Simon Plyte
  • Novel human homologue of the dbf4/ask1 protein, nucleic acids, and methods related to the same
    Publication number: 20040102611
    Abstract: The present invention provides a human polypeptide homolog of DBF4/ASK1 and polynucleotides which identify and encode DRF1. In addition, the invention provides expression vectors, host cells and methods for its production. The invention also provides methods for the identification of DRF1 or DRF1-containing complex agonists/antagonists, useful for the treatment of human diseases and conditions.
    Type: Application
    Filed: June 27, 2003
    Publication date: May 27, 2004
    Inventors: Jens Bethelsen, Roberta Bosotti, Antonella Isacchi, Simon Plyte
  • Human NIM1 kinase
    Publication number: 20030087317
    Abstract: The invention provides a human NIM1 kinase, an encoding nucleic acid molecule, and an antibody that specifically binds the protein. The invention also provides for the use of these compositions in the characterization, diagnosis, and treatment of disorders associated NIM1 kinase expression.
    Type: Application
    Filed: July 11, 2002
    Publication date: May 8, 2003
    Applicant: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Angela Molteni, Paola Magnaghi, Roberta Bosotti, Emanuela Scacheri, Antonella Isacchi, David M. Hodgson
  • Human NIM1 kinase
    Patent number: 6458561
    Abstract: The invention provides a nucleic acid molecule which encodes the human NIM1 kinase. It also provides for the use of the nucleic acid molecule, fragments, variants and complements thereof and of the protein, portions thereof and antibodies thereto for characterization, diagnosis, evaluation, treatment, or prevention of disorders associated with expression. The invention additionally provides expression vectors and host cells for the production of the protein and a transgenic organism or model system.
    Type: Grant
    Filed: March 13, 2000
    Date of Patent: October 1, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Angela Molteni, Paola Magnaghi, Roberta Bosotti, Emanuela Scacheri, Antonella Isacchi, David M. Hodgson