Patents by Inventor Roberta Cozzi

Roberta Cozzi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLYPEPTIDE SCAFFOLD
    Publication number: 20260151472
    Abstract: The present invention relates to chimeric polypeptides comprising a scaffold polypeptide and one or more exogenous polypeptides, wherein the scaffold polypeptide comprises a backbone protein 2a (BP-2a) Domain 3 (D3) polypeptide in which at least one endogenous loop has been partially or wholly replaced by an exogenous polypeptide. The present invention also relates to nanoparticles, outer membrane vesicles, pharmaceutical compositions, vaccines, arrays and kits comprising said chimeric polypeptides, methods of their production, and uses thereof in therapy and antibody screening.
    Type: Application
    Filed: October 19, 2023
    Publication date: June 4, 2026
    Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Luigia CAPPELLI, Roberta COZZI
  • Novel Antigens
    Publication number: 20240115688
    Abstract: The present invention is directed to novel, modified FimH polypeptides, nucleic acids encoding them, and the use of the polypeptides and nucleic acids in the treatment and/or prevention of disease, in particular, urinary tract infection (UTI).
    Type: Application
    Filed: November 30, 2021
    Publication date: April 11, 2024
    Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Roberto ADAMO, Roberta COZZI, Adele FANTONI, Sanjay PHOGAT, Roberto ROSINI, Maria SCARSELLI, Newton WAHOME
  • DOCK TAG SYSTEM
    Publication number: 20230250142
    Abstract: Pairs of peptides capable of forming spontaneous covalent bonds, and their uses, such as in forming fusion proteins.
    Type: Application
    Filed: June 11, 2021
    Publication date: August 10, 2023
    Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Matthew James BOTTOMLEY, Roberta COZZI, Newton Muchugu WAHOME
  • BACTERIAL IMMUNIZATION USING NANOPARTICLE VACCINE
    Publication number: 20230210975
    Abstract: Methods of inducing an immunogenic response against a bacterial polysaccharide or oligosaccharide, and constructs and compositions for use in such methods.
    Type: Application
    Filed: June 11, 2021
    Publication date: July 6, 2023
    Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Roberto ADAMO, Filippo CARBONI, Roberta COZZI, Immaculada MARGARIT Y ROS, Maria Rosaria ROMANO
  • Carrier molecule for antigens
    Patent number: 10245310
    Abstract: The invention provides a conjugate comprising an antigen and a carrier molecule, wherein the carrier molecule comprises a BP-2a antigen and a spb1 antigen. BP-2a and spb1 are Streptococcus agalactiae antigens. The conjugate may be used in a method for raising an immune response in a mammal, the method comprising administering the conjugate to the mammal. Also provided are pharmaceutical compositions, particularly vaccines, comprising the conjugate.
    Type: Grant
    Filed: August 5, 2015
    Date of Patent: April 2, 2019
    Assignee: GlaxoSmithKline Biologicals SA
    Inventors: Francesco Berti, Roberta Cozzi, Domenico Maione, Cira Daniela Rinaudo, Immaculada Margarit Y Ros, Guido Grandi
  • CARRIER MOLECULE FOR ANTIGENS
    Publication number: 20170224803
    Abstract: The invention provides a conjugate comprising an antigen and a carrier molecule, wherein the carrier molecule comprises a BP-2a antigen and a spb1 antigen. BP-2a and spb1 are Streptococcus agalactiae antigens. The conjugate may be used in a method for raising an immune response in a mammal, the method comprising administering the conjugate to the mammal. Also provided are pharmaceutical compositions, particularly vaccines, comprising the conjugate.
    Type: Application
    Filed: August 5, 2015
    Publication date: August 10, 2017
    Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Francesco BERTI, Roberta COZZI, Domenico MAIONE, Cira Daniela RINAUDO, Immaculada MARGARIT Y ROS, Guido GRANDI
  • PILUS PROTEINS AND COMPOSITIONS
    Publication number: 20150273042
    Abstract: The invention provides methods of forming pili in vitro and proteins suitable for use in these methods. The invention also provides pili produced by these methods and compositions comprising these pili for the treatment and prevention of bacterial disease, in particular of conditions caused by Streptococcus.
    Type: Application
    Filed: February 23, 2013
    Publication date: October 1, 2015
    Inventors: Domenico Maione, Immaculada Margarit Y Ros, Roberta Cozzi, Cira Daniela Rinaudo, Maddalena Lazzarin, Francesca Zerbini