Patents by Inventor Roberta Lynn Jackson

Roberta Lynn Jackson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Reporter gene system for use in cell-based assessment of inhibitors of the hepatitis C virus protease
    Patent number: 6790612
    Abstract: A cell-based assay system in which the detection of the reporter gene activity, or secreted alkaline phosphatase (SEAP), is dependent upon the protease activity of the Hepatitis C virus NS3 gene product. This system can be used to assess the activity of candidate protease inhibitors in a mammalian cell-based assay system. The assay system is simpler than previously described assays due to the use of SEAP which allows the reporter gene activity to be quantified by measuring the amount of secreted gene product in the cell media by monitoring the conversion of luminescent or calorimetric alkaline phosphatase substrate.
    Type: Grant
    Filed: July 10, 2002
    Date of Patent: September 14, 2004
    Assignee: Agouron Pharmaceuticals, Inc.
    Inventors: Karen Elizabeth Potts, Roberta Lynn Jackson, Amy Karen Patick
  • Reporter gene system for use in cell-based assessment of inhibitors of the hepatitis C virus protease
    Publication number: 20030175692
    Abstract: A cell-based assay system in which the detection of the reporter gene activity, or secreted alkaline phosphatase (SEAP), is dependent upon the protease activity of the Hepatitis C virus NS3 gene product. This system can be used to assess the activity of candidate protease inhibitors in a mammalian cell-based assay system. The assay system is simpler than previously described assays due to the use of SEAP which allows the reporter gene activity to be quantified by measuring the amount of secreted gene product in the cell media by monitoring the conversion of luminescent or calorimetric alkaline phosphatase substrate.
    Type: Application
    Filed: July 10, 2002
    Publication date: September 18, 2003
    Applicant: Agouron Pharmaceuticals, Inc.
    Inventors: Karen Elizabeth Potts, Roberta Lynn Jackson, Amy Karen Patick
  • Reporter gene system for use in cell-based assessment of inhibitors of the hepatitis C virus protease
    Patent number: 6599738
    Abstract: A cell-based assay system in which the detection of the reporter gene activity, or secreted alkaline phosphatase (SEAP), is dependent upon the protease activity of the Hepatitis C virus NS3 gene product. This system can be used to assess the activity of candidate protease inhibitors in a mammalian cell-based assay system. The assay system is simpler than previously described assays due to the use of SEAP which allows the reporter gene activity to be quantified by measuring the amount of secreted gene product in the cell media by monitoring the conversion of luminescent or colorimetric alkaline phosphatase substrate.
    Type: Grant
    Filed: August 2, 2001
    Date of Patent: July 29, 2003
    Assignee: Agouron Pharmaceuticals, Inc.
    Inventors: Karen Elizabeth Potts, Roberta Lynn Jackson, Amy Karen Patick
  • Reporter gene system for use in cell-based assessment of inhibitors of the hepatitis C virus protease
    Publication number: 20030082518
    Abstract: A cell-based assay system in which the detection of the reporter gene activity, or secreted alkaline phosphatase (SEAP), is dependent upon the protease activity of the Hepatitis C virus NS3 gene product. This system can be used to assess the activity of candidate protease inhibitors in a mammalian cell-based assay system. The assay system is simpler than previously described assays due to the use of SEAP which allows the reporter gene activity to be quantified by measuring the amount of secreted gene product in the cell media by monitoring the conversion of luminescent or calorimetric alkaline phosphatase substrate.
    Type: Application
    Filed: August 2, 2001
    Publication date: May 1, 2003
    Applicant: Agouron Pharmaceuticals, Inc.
    Inventors: Karen Elizabeth Potts, Roberta Lynn Jackson, Amy Karen Patick
  • Reporter gene system for use in cell-based assessment of inhibitors of the Hepatitis C virus protease
    Patent number: 6280940
    Abstract: A cell-based assay system in which the detection of the reporter gene activity, or secreted alkaline phosphatase (SEAP), is dependent upon the protease activity of the Hepatitis C virus NS3 gene product. This system can be used to assess the activity of candidate protease inhibitors in a mammalian cell-based assay system. The assay system is simpler than previously described assays due to the use of SEAP which allows the reporter gene activity to be quantified by measuring the amount of secreted gene product in the cell media by monitoring the conversion of luminescent or calorimetric alkaline phosphatase substrate.
    Type: Grant
    Filed: March 8, 1999
    Date of Patent: August 28, 2001
    Assignee: Agouron Pharmaceuticals, Inc.
    Inventors: Karen Elizabeth Potts, Roberta Lynn Jackson, Amy Karen Patick