Patents by Inventor Roberto A. DePaz

Roberto A. DePaz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Alphavirus and alphavirus replicon particle formulations and methods
    Patent number: 9187729
    Abstract: Disclosed are methods for preparing dried (preferably lyophilized) preparations comprising a population of alphaviruses or alphavirus replicon particles, a sugar or polyol, a surfactant and a salt and preparations made by these methods, both in the dried form but also as liquids prior to drying or after reconstituting dried preparations. These preparations may further comprise a plasticizer and/or a bulking agent. These preparations are readily reconstituted, with little or no loss in infectivity of the viruses or replicon particles.
    Type: Grant
    Filed: January 24, 2011
    Date of Patent: November 17, 2015
    Assignee: ALPHAVAX, INC.
    Inventors: Roberto A. DePaz, Todd L. Talarico
  • Alphavirus and Alphavirus Replicon Particle Formulations and Methods
    Publication number: 20110182941
    Abstract: Disclosed are methods for preparing dried (preferably lyophilized) preparations comprising a population of alphaviruses or alphavirus replicon particles, a sugar or polyol, a surfactant and a salt and preparations made by these methods, both in the dried form but also as liquids prior to drying or after reconstituting dried preparations. These preparations may further comprise a plasticizer and/or a bulking agent. These preparations are readily reconstituted, with little or no loss in infectivity of the viruses or replicon particles.
    Type: Application
    Filed: January 24, 2011
    Publication date: July 28, 2011
    Applicant: AlphaVax, Inc.
    Inventors: Roberto A. DePaz, Todd L. Talarico
  • Alphavirus and Alphavirus Replicon Particle Formulations and Methods
    Publication number: 20090047255
    Abstract: Disclosed are methods for preparing dried (preferably lyophilized) preparations comprising a population of alphaviruses or alphavirus replicon particles, a sugar or polyol, a surfactant and a salt and preparations made by said methods, both in the dried form but also as liquids prior to drying or after reconstituting dried preparations. These preparations may further comprise a plasticizer and/or a bulking agent. These preparations are readily reconstituted, with little or no loss in infectivity of the viruses or replicon particles.
    Type: Application
    Filed: November 2, 2007
    Publication date: February 19, 2009
    Applicant: AlphaVax, Inc.
    Inventors: Roberto A. DePaz, Todd L. Talarico