Patents by Inventor Roberto Angelo Motterlini

Roberto Angelo Motterlini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic delivery of carbon monoxide
    Patent number: 8389572
    Abstract: Compounds, pharmaceutical compositions and methods for the therapeutic delivery of carbon monoxide to humans and other mammals that employ transition metal complexes having at least a substituted cyclopentadienyl, indenyl or fluorenyl ligand and two or more carbonyl ligands.
    Type: Grant
    Filed: January 23, 2007
    Date of Patent: March 5, 2013
    Assignee: hemoCORM Limited
    Inventors: Roberto Angelo Motterlini, Brian Ernest Mann, Tony Richard Johnson, David Alistair Scapens, Rehan Aqil, Trevor Perrior
  • Therapeutic delivery of carbon monoxide
    Patent number: 8236339
    Abstract: Metal carbonyls are used to deliver CO having biological activity, for example vasodilatation and inhibition of transplant rejection. The metal of the carbonyl is typically of groups 7 to 10, e.g. Fe and Ru. The carbonyl preferably has one or store ligands other than CO, such as amine acids, to modulate the CO release property and solubility.
    Type: Grant
    Filed: January 27, 2006
    Date of Patent: August 7, 2012
    Assignee: hemoCORM Limited
    Inventors: Roberto Angelo Motterlini, Brian Ernest Mann
  • Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs
    Patent number: 7989650
    Abstract: Metal carbonyls are used to deliver CO to organs to limit post-ischaemic damage. The organ may be extracorporeal, e.g. for use in a transplant, or may be an isolated organ inside or attached to the body but isolated from the blood flow. The carbonyl preferably has one or more other ligands other than CO, such as amino acids, to modulate the CO release property and solubility.
    Type: Grant
    Filed: November 20, 2003
    Date of Patent: August 2, 2011
    Assignee: hemoCORM Limited
    Inventors: Roberto Angelo Motterlini, Brian Ernest Mann
  • THERAPEUTIC DELIVERY OF CARBON MONOXIDE
    Publication number: 20110015263
    Abstract: Compounds, pharmaceutical compositions and methods for the therapeutic delivery of carbon monoxide to humans and other mammals that employ transition metal complexes having at least a substituted cyclopentadienyl, indenyl or fluorenyl ligand and two or more carbonyl ligands.
    Type: Application
    Filed: January 23, 2007
    Publication date: January 20, 2011
    Inventors: Roberto Angelo Motterlini, Brian Ernest Mann, Tony Richard Johnson, David Alistair Scapens, Rehan Aqil, Trevor Perrior
  • Therapeutic delivery of carbon monoxide
    Publication number: 20100105770
    Abstract: Compounds, pharmaceutical compositions and methods for the therapeutic delivery of carbon monoxide to humans and other mammals that employ Mn complexes having CO ligands, and additional halogen, monodentate and/or bidentate ligands, wherein the additional ligands do not occupy trans positions relative to each other.
    Type: Application
    Filed: July 4, 2007
    Publication date: April 29, 2010
    Inventors: Roberto Angelo Motterlini, Brian Ernest Mann, David Alistair Scapens
  • Electrode Calibration
    Publication number: 20080121012
    Abstract: A method and kit for calibrating a CO-concentration sensing electrode that employs a standard solution obtained by dissolving a predetermined amount of a CO-releasing boranocarbonate to provide a known concentration of CO.
    Type: Application
    Filed: May 20, 2005
    Publication date: May 29, 2008
    Inventor: Roberto Angelo Motterlini
  • Therapeutic delivery of carbon monoxide
    Patent number: 7045140
    Abstract: Metal carbonyls are used to deliver CO having biological activity, for example vasodilatation and inhibition of transplant rejection. The metal of the carbonyl is typically of groups 7 to 10, e.g. Fe and Ru. The carbonyl preferably has one or more ligands other than CO, such as amino acids, to modulate the CO release property and solubility.
    Type: Grant
    Filed: May 14, 2002
    Date of Patent: May 16, 2006
    Assignee: Hemocorm Limited
    Inventors: Roberto Angelo Motterlini, Brian Ernest Mann
  • Therapeutic delivery of carbon monoxide
    Publication number: 20030064114
    Abstract: Metal carbonyls are used to deliver CO having biological activity, for example vasodilatation and inhibition of transplant rejection. The metal of the carbonyl is typically of groups 7 to 10, e.g. Fe and Ru. The carbonyl preferably has one or more ligands other than CO, such as amino acids, to modulate the CO release property and solubility.
    Type: Application
    Filed: May 14, 2002
    Publication date: April 3, 2003
    Inventors: Roberto Angelo Motterlini, Brian Ernest Mann