Patents by Inventor Roberto Arnaldo Calle

Roberto Arnaldo Calle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATIONS OF DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITORS AND ACETYL-COA CARBOXYLASE INHIBITOR
    Publication number: 20230405002
    Abstract: Described herein are pharmaceutical compositions comprising 2-{5-[(3-ethoxypyridin-2-yl)oxy]pyridin-3-yl}-N-[(3S,5S)-5-fluoropiperidin-3-yl]pyrimidine-5-carboxamide, or pharmaceutically acceptable salt thereof, for treatment of liver disease and diseases related thereto. Also described are compositions comprising 2-{5-[(3-ethoxypyridin-2-yl)oxy]pyridin-3-yl}-N-[(3S,5S)-5-fluoropiperidin-3-yl]pyrimidine-5-carboxamide, or pharmaceutically acceptable salt thereof and 4-(4-(1-Isopropyl-7-oxo-1,4,6,7-tetrahydrospiro[indazole-5,4?-piperidine]-1?-carbonyl)-6-methoxypyridin-2-yl)benzoic acid, or pharmaceutically acceptable salt thereof, for treatment of liver disease and diseases related thereto.
    Type: Application
    Filed: February 22, 2021
    Publication date: December 21, 2023
    Applicant: Pfizer Inc.
    Inventors: Neeta Balkrishan Amin, Arthur James Bergman, Roberto Arnaldo Calle, Robert Gregory Dullea, David James Edmonds, William Paul Esler, Kevin James Filipski, James Richard Gosset, Albert Myung Kim, Jeffrey Allen Pfefferkorn, Patrick Robert Verhoest
  • Combinations for Treatment of NAFLD/NASH and Related Diseases
    Publication number: 20230218616
    Abstract: A method for treating fatty liver disease and related diseases or disorders with a therapeutically effective amount of a composition comprising from about 25 mg to about 1200 mg of (S)-2-(5-((3-ethoxypyridin-2-yl)oxy)pyridin-3-yl)-N-(tetrahydrofuran-3-yl)pyrimidine-5-carboxamide or a pharmaceutically acceptable salt thereof, and from about 5 mg to about 40 mg of 4-(4-(1-Isopropyl-7-oxo-1,4,6,7-tetrahydrospiro[indazole-5,4?-piperidine]-1?-carbonyl)-6-methoxypyridin-2-yl)benzoic acid or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: February 22, 2021
    Publication date: July 13, 2023
    Applicant: Pfizer Inc.
    Inventors: Neeta Balkrishan Amin, Arthur James Bergman, Roberto Arnaldo Calle, William Paul Esler, Albert Myung Kim, Jeffrey Allen Pfefferkorn, Patrick Robert Verhoest