Patents by Inventor Roberto Casagrande

Roberto Casagrande has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the resolution of 3-(4-substituted-phenyl)-glycidic acid derivatives
    Patent number: 5198557
    Abstract: A process for the kinetic resolution of cis or trans enantiomeric mixtures of the compounds of formula ##STR1## wherein R.sub.3 and X have the meanings reported in the specification and the asterisks mark the asymmetric carbon atoms, is described.The compounds of formula III-A are intermediates useful in the preparation of compounds active on the cardiovascular system.
    Type: Grant
    Filed: May 10, 1991
    Date of Patent: March 30, 1993
    Assignee: Zambon Group S.p.A.
    Inventors: Claudio Giordano, Roberto Casagrande
  • Process for the preparation of an intermediate of diltiazem
    Patent number: 5102999
    Abstract: A process for the preparation of intermediates useful for the synthesis of Diltiazem consisting in the racemization of (--)-cis-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H )-one is described.
    Type: Grant
    Filed: November 15, 1990
    Date of Patent: April 7, 1992
    Assignee: Zambon Group S.p.A.
    Inventors: Claudio Giordano, Roberto Casagrande
  • Resolution process of intermediates useful for the preparation of diltiazem
    Patent number: 5097059
    Abstract: A process of spontaneous resolution of compounds of formula ##STR1## wherein R has the meanings reported in the description, is described. The compounds of formula III are intermediates useful for the preparation of Diltiazem.
    Type: Grant
    Filed: July 26, 1990
    Date of Patent: March 17, 1992
    Assignee: Zambon Group S.p.A.
    Inventors: Claudio Giordano, Dario Tentorio, Roberto Casagrande, Placido Bertin, Valeriano Merli, Giorgio Sagramora
  • Process for preparing an organic synthesis intermediate
    Patent number: 5023381
    Abstract: A process is described for the preparation of 2-methoxy-6-propionyl-naphthalene, an intermediate in the synthesis of naproxen.The process consists of Friedel-Crafts acylation of 2-methoxy-naphthalene, and obviates the drawbacks related to the use of nitrobenzene as solvent.
    Type: Grant
    Filed: December 20, 1989
    Date of Patent: June 11, 1991
    Assignee: Zambon Group S.p.A.
    Inventors: Giulio Perdoncin, Claudio Giordano, Maurizio Paiocchi, Roberto Casagrande