Abstract: The invention is directed to processes for purifying the Anastrozole intermediate, 3,5-bis(2-cyanoisopropyl)toluene, processes for producing Anastrozole, processes for preparing Anastrozole pharmaceutical compositions, and Anastrozole and Anastrozole pharmaceutical compositions prepared with the processes of the invention.

Abstract: Provided are highly pure pemetrexed diacid and pharmaceutically acceptable salts thereof, and processes for their preparation.

Abstract: Reference markers and reference standards for the determination of impurities in Anastrozole are provided.

Abstract: This invention relates to solvates of tiotropium bromide having a purity of at least 99%, process for preparing such pure solvates, and their use in pharmaceutical formulations. This invention also provides tiotropium bromide solvates containing less than about 0.15% area by HPLC of 2,2-dithienyl glycolic acid.

Abstract: Reference markers and reference standards for the determination of impurities in Anastrozole are provided.

Abstract: The invention is directed to processes for purifying the Anastrozole intermediate, 3,5-bis(2-cyanoisopropyl)toluene, processes for producing Anastrozole, processes for preparing Anastrozole pharmaceutical compositions, and Anastrozole and Anastrozole pharmaceutical compositions prepared with the processes of the invention.

Abstract: The light box is provided with a case having arranged therein a reflector directed to the front wall to be illuminated from the rear. The reflector surf ace has a concave curvature. An elongated light source is arranged in the center of the case. The reflector, in the central area thereof, is covered by an optical film having a structured surface directed to the light source. This structure consists of immediately adjacent V-shaped grooves, being parallel to each other and running transverse to the extension of the light source. By total reflection on the structured surface of the transparent optical film as well as by reflection on the reflector surface of the reflector, the light of the light source incident on the reflector is reflected in the direction of the back-lit front side of the light box. This arrangement provides for improved and more-uniform light distribution.