Abstract: This invention relates to a container (1) which is pre-filled or pre-fillable with one or more substances, such as a medical liquid and similar, comprising a squeezable activation compartment (2) intended to contain said one or more substances, a dispensing compartment (3) including a first portion (31) equipped with at least one dispensing member (311, 312, 314) of said one or more substances, and a second portion (32), wherein said second portion (32) of said dispensing compartment (3) and said activation compartment (2) are fluid-dynamically connected, and an activator element (4) arranged inside said container (1). This invention also relates to a method for dispensing at least one substance by means of a container (1), and to a production method of a container (1).

Abstract: The present invention relates to an opening and liquid supplying system (100) for pre-filled containers (10, 30) equipped with a supplying end, comprising a coupling element (20), connecting means (6) movable from a first position to a second position, and movable protection means (9); the coupling element (20) has an end (27) closed and suitable for being punched, and first guiding means (21) for guiding the movement of the connecting means (6) movable from the first position, close to the closed end (27), to the second position, apart from such end, and vice versa; the connecting means (6) have engaging means (7) for engaging with the protection means (9) so as to move integrally along a second degree of freedom, different than the first degree of freedom, and first matches (11) for the first guiding means (21). The invention relates also to a respective pre-filled container equipped with such system and the method for realize them.

Abstract: The invention relates to a watertight closing device (100, 200) for an aseptic container, comprising an external shell (10, 210) made up of a first protecting material, a nucleus (20, 220) made up of a second material suitable for being punched, and a tab (11, 211) equipped with a first free end (12, 212) and with a second end (13, 213) connected to the shell (10, 210). The nucleus (20, 220) has a protruding element (21, 221) placed in correspondence with the connection area (14, 214), so that the protruding element (21, 221) is directly connected to the second end (13, 213) of the tab (11, 211).

Abstract: Described is an insert for packaging pre-filled enemas equipped with a supplying end, comprising a first end for the coupling with the enema, a second end for the dispensing, and removable protection means, at the second end. The invention relates to a pre-filled enema comprising the insert.

Abstract: The invention relates to a process for producing and assembling an aseptic container (100, 200) suitable for containing and supplying medical liquids comprising in sequence at least the steps of extruding a plastic material, operating on the intermediate tubular element obtained by blow moulding so as to obtain at least a hollow body (2, 202) and sealing the hollow body (2, 202) with a cap having a small size or applying an insert, comprising at least a portion (4, 204) with facilitated breakage.

Abstract: The invention relates to a watertight closing device (100, 200) for an aseptic container, comprising an external shell (10, 210) made up of a first protecting material, a nucleus (20, 220) made up of a second material suitable for being punched, and a tab (11, 211) equipped with a first free end (12, 212) and with a second end (13, 213) connected to the shell (10, 210). The nucleus (20, 220) has a protruding element (21, 221) placed in correspondence with the connection area (14, 214), so that the protruding element (21, 221) is directly connected to the second end (13, 213) of the tab (11, 211).

Abstract: A closure system and method of forming containers comprising a closing element. The closing element is integrally sealable to the container at one of the openings to be closed, and a preferential separation zone between the container and the closing element, the closure system comprising a first guiding and/or coupling portion for guiding and controlling the movement of the closing element from a first blocking position, wherein the closing element is integral to the container, to a second unblocking position, wherein the closing element is separated from the container via the preferential separation zone. The closure system further includes a first thread on the insert and a second thread formed within the closing element.

Abstract: The present invention relates to an opening and liquid supplying system (100) for pre-filled containers (10, 30) equipped with a supplying end, comprising a coupling element (20), connecting means (6) movable from a first position to a second position, and movable protection means (9); the coupling element (20) has an end (27) closed and suitable for being punched, and first guiding means (21) for guiding the movement of the connecting means (6) movable from the first position, close to the closed end (27), to the second position, apart from such end, and vice versa; the connecting means (6) have engaging means (7) for engaging with the protection means (9) so as to move integrally along a second degree of freedom, different than the first degree of freedom, and first matches (11) for the first guiding means (21). The invention relates also to a respective pre-filled container equipped with such system and the method for realize them.

Abstract: The invention relates to a process for producing and assembling an aseptic container (100, 200) suitable for containing and supplying medical liquids comprising in sequence at least the steps of extruding a plastic material, operating on the intermediate tubular element obtained by blow moulding so as to obtain at least a hollow body (2, 202) and sealing the hollow body (2, 202) with a cap having a small size or applying an insert, comprising at least a portion (4, 204) with facilitated breakage.

Abstract: A process for producing and assembling a medical operations syringe (20) comprising in the order the operations of extruding plastic material in order to obtain an intermediate tubular element (1) made of plastic material at least partially at molten state, performing on the intermediate tubular element (1) a blow molding in order to obtain at least a hollow body (2), inserting firmly and at least partially a thrust piston (3) into the hollow body (2) immediately after the blow molding operation.

Abstract: The present invention relates to a a closure system for containers comprising a closing element (1) integrally sealable to the container (10) at one of its openings (3) to be closed, and a preferential separation zone (11) between said container (10) and said closing element (1), said closure system (C) being characterized in comprising first guiding and/or coupling means (A, 12, 13) for guiding and controlling the movement of the closing element (1) from a first blocking position, wherein the closing element (1) is integral to the container (10), to a second unblocking position, wherein the closing element (1) is apart from the container (10) in correspondence of the preferential separation zone (11) having, as guide means for opening, a first thread (13) on the insert (12) and a second thread (4) formed within the closing element (1).

Abstract: A process for producing medical instruments (7) comprising the operations of extruding plastic material in order to obtain a heated tubular element (1) made of molten state plastic material, performing on the tubular element (1) a blow molding in order to obtain a plurality of medical containers (6). The process comprises the operation of calibrating the inner surface (6a) of the various medical containers (6), performed after the operation of extruding plastic material, in order to make smooth and continuous the inner surface (6a) of each of the medical containers (6).

Abstract: A perforable closure for a container, is provided with at least a annular portion (2) fit to joint the container and connected to an end portion (3), perforable by means of a perforator (P) of an outflow or the like. At least the annular (2) and end (3) portions of said closure (1) are integral.

Abstract: A process for producing medical instruments (7) comprising the operations of extruding plastic material in order to obtain a heated tubular element (1) made of molten state plastic material, performing on the tubular element (1) a blow moulding in order to obtain a plurality of medical containers (6). The process comprises the operation of calibrating the inner surface (6a) of the various medical containers (6), performed after the operation of extruding plastic material, in order to make smooth and continuous the inner surface (6a) of each of the medical containers (6).

Abstract: A process for producing and assembling a medical operations syringe (20) comprising in the order the operations of extruding plastic material in order to obtain an intermediate tubular element (1) made of plastic material at least partially at molten state, performing on the intermediate tubular element (1) a blow moulding in order to obtain at least a hollow body (2), inserting firmly and at least partially a thrust piston (3) into the hollow body (2) immediately after the blow moulding operation.

Abstract: A perforable closure for a container, is provided with at least a annular portion (2) fit to joint the container and connected to an end portion (3), perforable by means of a perforator (P) of an outflow or the like. At least the annular (2) and end (3) portions of said closure (1) are integral.