Patents by Inventor Roberto Dal Toso

Roberto Dal Toso has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12076434
    Abstract: The method for producing a plant cell extract of hydroxyl rich glycoproteins (HRGP), including extensins, by extraction from plant cell walls (PCW), comprises subjecting a biomass of whole dedifferentiated plant cells to the following treatment: —Breaking the cells for producing a cell homogenate in which the intracellular molecules are solubilized; —Eliminating the solubilized intracellular molecules by washing the cell homogenate with water and diafiltering on a 0.2 ?m filter; —Extracting the HRGP from the PCW by adding a salt thereby forming an HRGP enriched salted extract suspension; —Filtering the HRGP enriched salted extract suspension to discard the PCW debris and recover the desired enriched HRGP salted extract.
    Type: Grant
    Filed: July 4, 2019
    Date of Patent: September 3, 2024
    Assignee: Croda Italiana S.P.A.
    Inventors: Chiara Marzotto, Roberto Dal Toso
  • Publication number: 20210169775
    Abstract: The method for producing a plant cell extract of hydroxyl rich glycoproteins (HRGP), including extensins, by extraction from plant cell walls (PCW), comprises subjecting a biomass of whole dedifferentiated plant cells to the following treatment: —Breaking the cells for producing a cell homogenate in which the intracellular molecules are solubilized; —Eliminating the solubilized intracellular molecules by washing the cell homogenate with water and diafiltering on a 0.2 ?m filter; —Extracting the HRGP from the PCW by adding a salt thereby forming an HRGP enriched salted extract suspension; —Filtering the HRGP enriched salted extract suspension to discard the PCW debris and recover the desired enriched HRGP salted extract.
    Type: Application
    Filed: July 4, 2019
    Publication date: June 10, 2021
    Applicant: Croda Italiana S.P.A
    Inventors: Chiara Marzotto, Roberto Dal Toso
  • Patent number: 10456434
    Abstract: The present invention refers to the use of extracts from selected and stabilized cell lines comprising phenylpropanoids with high anti-oxidant capacity having a verbascoside titer of between 20% and 90% and a chromophore-free fraction of between 80% and 10%, in human and veterinary medicine, and for nutritional and cosmetic purposes.
    Type: Grant
    Filed: May 14, 2010
    Date of Patent: October 29, 2019
    Assignee: CRODA ITALIANA S. P. A.
    Inventors: Renzo Dal Monte, Roberto Dal Toso, Anacleto Minghetti, Nicoletta Crespi Perellino, Giovanna Pressi
  • Patent number: 9623063
    Abstract: The present invention relates to selected and stabilized cell line extracts from Ajuga reptans comprising phenylpropanoids having high antioxidating capacity with a teupolioside titer of between 20% and 90% and a chromophore-free fraction of between 80% and 10%. Said extracts are for use in human and veterinary therapy and for nutritional and cosmetic purposes. Furthermore, the invention relates to a novel phenylpropanoid molecule denominated isoteupolioside.
    Type: Grant
    Filed: June 19, 2006
    Date of Patent: April 18, 2017
    Assignee: I.R.B. ISTITUTO DI RICERCHE BIOTECNOLOGICHE S.r.l.
    Inventors: Renzo Dal Monte, Roberto Dal Toso, Anacleto Minghetti, Nicoletta Crespi Perellino, Giovanna Pressi
  • Patent number: 8709810
    Abstract: The present invention relates to the preparation of plant cell cultures belonging to the Dendrobium Phalaenopsis, Ansellia, Polyrrhiza, Vanilla, Cattleya and Vanda genera and their use in cosmetic, nutritional and pharmaceutical fields. In particular, the present invention regards a selected cell culture of meristematic cells of plants belonging to the Dendrobium Phalaenopsis, Ansellia, Polyrrhiza, Vanilla, Cattleya and Vanda genera characterized in that it contains an amount of phenylpropanoids greater than 0.1% expressed on the cell dry weight and an amount of hydrosoluble polysaccharides greater than 5% expressed on the cell dry weight, as well as preparations, pharmaceutical and cosmetic compositions or food supplements containing the cell culture.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: April 29, 2014
    Assignee: I.R.B. Istituto di Ricerche Biotechnologiche S.r.l.
    Inventors: Giovanna Pressi, Roberto Dal Toso, Elena Sgaravatti
  • Patent number: 8592203
    Abstract: A process for producing a bioreactor using viable immobilized biological material. The process produces a siliceous layer capable of biomass immobilization and selectively cutting off of macromolecules having a molecular weight higher than a selected threshold. The process includes the steps of: (a) supplying a gas flow of a gas carrier saturated by a mixture of silicon alkoxides selected from the group comprising (1) Si(OR)4, (2) SiH(OR)3, (3) R?Si(OR)3 and (4) R?SiH(OR)2 wherein R and R?, equal or different each other, are alkyl and/or aryl groups, wherein said gas flow is prepared by bubbling the gas carrier into a liquid mixture of said alkoxides in the ratio of (1) 40-85/(2) 0-60/(3) 0-60/(4) 0-60 (% v/v), preferably in the ratio of (1) 40-85/(2) 0-50/(3) 0-50/(4) 0-50 (% v/v), more preferably in the ratio of (1) 50-80/(2) 0-20/(3) 5-30/(4) 5-30 (% v/v), at a temperature of from 20 to 180° C., preferably of from 20 to 100° C.
    Type: Grant
    Filed: May 10, 2007
    Date of Patent: November 26, 2013
    Assignee: Silbiotec Due S.A.
    Inventors: Gianni Carturan, Roberto Dal Toso, Renzo Dal Monte
  • Publication number: 20130022580
    Abstract: The present invention relates to the preparation of plant cell cultures belonging to the Dendrobium Phalaenopsis, Anisellia, Polyrrhiza, Vanilla, Cattleya and Vanda genera and their use in cosmetic, nutritional and pharmaceutical fields. In particular, the present invention regards a selected cell culture of meristematic cells of plants belonging to the Dendrobium Phalaenopsis, Anisellia, Polyrrhiza, Vanilla, Cattleya and Vanda genera characterized in that it contains an amount of phenylpropanoids greater than 0.1% expressed on the cell dry weight and an amount of hydrosoluble polysaccharides greater than 5% expressed on the cell dry weight, as well as preparations, pharmaceutical and cosmetic compositions or food supplements containing said cell culture.
    Type: Application
    Filed: November 11, 2011
    Publication date: January 24, 2013
    Inventors: Giovanna Pressi, Roberto Dal Toso, Elena Sgaravatti
  • Publication number: 20110123646
    Abstract: The present invention refers to the use of extracts from selected and stabilised cell lines comprising phenylpropanoids with high anti-oxidant capacity having a verbascoside titre of between 20% and 90% and a chromophore-free fraction of between 80% and 10%, in human and veterinary medicine, and for nutritional and cosmetic purposes.
    Type: Application
    Filed: May 14, 2010
    Publication date: May 26, 2011
    Applicant: I.R.B. ISTITUTO DI RICERCHE BIOTECNOLOGICHE S.R.L.
    Inventors: Renzo Dal Monte, Roberto Dal Toso, Anacleto Minghetti, Nicoletta Crespi Perellino, Giovanna Pressi
  • Patent number: 7718199
    Abstract: The present invention refers to the use of extracts from selected and stabilized cell lines comprising phenylpropanoids with high anti-oxidant capacity having a verbascoside titre of between 20% and 90% and a chromophore-free fraction of between 80% and 10%, in human and veterinary medicine, and for nutritional and cosmetic purposes.
    Type: Grant
    Filed: June 19, 2006
    Date of Patent: May 18, 2010
    Assignee: I.R.B. Istituto di Ricerche Biotecnologiche S.r.l.
    Inventors: Renzo Dal Monte, Roberto Dal Toso, Anacleto Minghetti, Nicoletta Crespi Perellino, Giovanna Pressi
  • Patent number: 7625883
    Abstract: Optionally O-substituted glycero-phosphoinositol derivatives, their analogues and their salts wherein the substitutents: R?1, R?2, R2, R3, R4, R5, R6 have the described meaning, their synthesis and their pharmacological effect as modulators of the activation or over-stimulation of cPLA2.
    Type: Grant
    Filed: November 7, 2000
    Date of Patent: December 1, 2009
    Assignee: I.R.B. Istituto di Ricerche Biotechnologiche S.R.L.
    Inventors: Daniela Corda, Roberto Dal Toso, Giovanna Bonvento, Gabriele Marcolongo, Renzo Dal Monte
  • Publication number: 20070280984
    Abstract: A process for producing a bioreactor using viable immobilized biological material. The process produces a siliceous layer capable of biomass immobilization and selectively cutting off of macromolecules having a molecular weight higher than a selected threshold. The process includes the steps of: (a) supplying a gas flow of a gas carrier saturated by a mixture of silicon alkoxides selected from the group comprising (1) Si(OR)4, (2) SiH(OR)3, (3) R?Si(OR)3 and (4) R?SiH(OR)2 wherein R and R?, equal or different each other, are alkyl and/or aryl groups, wherein said gas flow is prepared by bubbling the gas carrier into a liquid mixture of said alkoxides in the ratio of (1) 40-85/(2) 0-60/(3) 0-60/(4) 0-60 (% v/v), preferably in the ratio of (1) 40-85/(2) 0-50/(3) 0-50/(4) 0-50 (% v/v), more preferably in the ratio of (1) 50-80/(2) 0-20/(3) 5-30/(4) 5-30 (% v/v), at a temperature of from 20 to 180° C., preferably of from 20 to 100° C.
    Type: Application
    Filed: May 10, 2007
    Publication date: December 6, 2007
    Inventors: Gianni Carturan, Roberto Dal Toso, Renzo Dal Monte
  • Patent number: 7229808
    Abstract: The present invention relates to a process for producing a bioreactor using viable immobilized biological material and to the bioreactor itself. More particularly, the present invention relates to a process for producing a siliceous layer capable of biomass immobilization and selectively cutting off macromolecules having a molecular weight higher than a selected threshold, comprising the steps of: a) supplying a gas flow of a gas carrier saturated by a mixture of silicon alkoxides selected from the group comprising (1)Si(OR)4, (2)SiH(OR)3, (3)R?Si(OR)3 and (4)R?SiH(OR)2 wherein R and R?, equal or different each other, are alkyl and/or aryl groups, wherein said gas flow is prepared by bubbling the gas carrier into a liquid mixture of said alkoxides in the ratio of (1)40–85/(2)0–60/(3)0–60/(4)0–60 (% v/v), preferably in the ratio of (1)40–85/(2)0–50/(3)0–50/(4)0–50 (% v/v), more preferably in the ratio of (1)50–80/(2)0–20/(3)5–30/(4)5–30 (% v/v), at a temperature of from 20 to 180° C.
    Type: Grant
    Filed: January 18, 2002
    Date of Patent: June 12, 2007
    Assignee: Silbiotec Due S.A.
    Inventors: Gianni Carturan, Roberto Dal Toso, Renzo Dal Monte
  • Publication number: 20070015262
    Abstract: The present invention relates to selected and stabilized cell line extracts from Ajuga reptans comprising phenylpropanoids having high antioxidating capacity with a teupolioside titre of between 20% and 90% and a chromophore-free fraction of between 80% and 10%. Said extracts are for use in human and veterinary therapy and for nutritional and cosmetic purposes. Furthermore, the invention relates to a novel phenylpropanoid molecule denominated isoteupolioside.
    Type: Application
    Filed: June 19, 2006
    Publication date: January 18, 2007
    Applicant: I.R.B. ISTITUTO DI RICERCHE BIOTECNOLOGICHE S.r.l.
    Inventors: Renzo Dal Monte, Roberto Dal Toso, Anacleto Minghetti, Nicoletta Crespi Perellino, Giovanna Pressi
  • Publication number: 20070004011
    Abstract: The present invention refers to the use of extracts from selected and stabilised cell lines comprising phenylpropanoids with high anti-oxidant capacity having a verbascoside titre of between 20% and 90% and a chromophore-free fraction of between 80% and 10%, in human and veterinary medicine, and for nutritional and cosmetic purposes.
    Type: Application
    Filed: June 19, 2006
    Publication date: January 4, 2007
    Applicant: I.R.B. ISTITUTO DI RICERCHE BIOTECNOLOGICHE S.r.I.
    Inventors: Renzo Dal Monte, Roberto Dal Toso, Anacleto Minghetti, Nicoletta Crespi Perellino, Giovanna Pressi
  • Publication number: 20050084944
    Abstract: The present invention relates to a process for producing a bioreactor using viable immobilized biological material and to the bioreactor itself. More particularly, the present invention relates to a process for producing a siliceous layer capable of biomass immobilization and selectively cutting off macromolecules having a molecular weight higher than a selected threshold, comprising the steps of: a) supplying a gas flow of a gas carrier saturated by a mixture of silicon alkoxides selected from the group comprising (1) Si(OR)4, (2) SiH(OR)3, (3) R?Si(OR)3 and (4) R?SiH(OR)2 wherein R and R?, equal or different each other, are alkyl and/or aryl groups, wherein said gas flow is prepared by bubbling the gas carrier into a liquid mixture of said alkoxides in the ratio of (1) 40-85/(2) 0-60/(3) 0-60/(4) 0-60 (% v/v), preferably in the ratio of (1) 40-85/(2) 0-50/(3) 0-50/(4) 0-50 (% v/v), more preferably in the ratio of (1) 50-80/(2) 0-20/(3) 5-30/(4) 5-30 (% v/v), at a temperature of from 20 to 180° C.
    Type: Application
    Filed: January 18, 2002
    Publication date: April 21, 2005
    Inventors: Gianni Carturan, Roberto Dal Toso, Renzo Dal Monte