Patents by Inventor Roberto Dal Toso
Roberto Dal Toso has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12076434Abstract: The method for producing a plant cell extract of hydroxyl rich glycoproteins (HRGP), including extensins, by extraction from plant cell walls (PCW), comprises subjecting a biomass of whole dedifferentiated plant cells to the following treatment: —Breaking the cells for producing a cell homogenate in which the intracellular molecules are solubilized; —Eliminating the solubilized intracellular molecules by washing the cell homogenate with water and diafiltering on a 0.2 ?m filter; —Extracting the HRGP from the PCW by adding a salt thereby forming an HRGP enriched salted extract suspension; —Filtering the HRGP enriched salted extract suspension to discard the PCW debris and recover the desired enriched HRGP salted extract.Type: GrantFiled: July 4, 2019Date of Patent: September 3, 2024Assignee: Croda Italiana S.P.A.Inventors: Chiara Marzotto, Roberto Dal Toso
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Publication number: 20210169775Abstract: The method for producing a plant cell extract of hydroxyl rich glycoproteins (HRGP), including extensins, by extraction from plant cell walls (PCW), comprises subjecting a biomass of whole dedifferentiated plant cells to the following treatment: —Breaking the cells for producing a cell homogenate in which the intracellular molecules are solubilized; —Eliminating the solubilized intracellular molecules by washing the cell homogenate with water and diafiltering on a 0.2 ?m filter; —Extracting the HRGP from the PCW by adding a salt thereby forming an HRGP enriched salted extract suspension; —Filtering the HRGP enriched salted extract suspension to discard the PCW debris and recover the desired enriched HRGP salted extract.Type: ApplicationFiled: July 4, 2019Publication date: June 10, 2021Applicant: Croda Italiana S.P.AInventors: Chiara Marzotto, Roberto Dal Toso
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Patent number: 10456434Abstract: The present invention refers to the use of extracts from selected and stabilized cell lines comprising phenylpropanoids with high anti-oxidant capacity having a verbascoside titer of between 20% and 90% and a chromophore-free fraction of between 80% and 10%, in human and veterinary medicine, and for nutritional and cosmetic purposes.Type: GrantFiled: May 14, 2010Date of Patent: October 29, 2019Assignee: CRODA ITALIANA S. P. A.Inventors: Renzo Dal Monte, Roberto Dal Toso, Anacleto Minghetti, Nicoletta Crespi Perellino, Giovanna Pressi
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Patent number: 9623063Abstract: The present invention relates to selected and stabilized cell line extracts from Ajuga reptans comprising phenylpropanoids having high antioxidating capacity with a teupolioside titer of between 20% and 90% and a chromophore-free fraction of between 80% and 10%. Said extracts are for use in human and veterinary therapy and for nutritional and cosmetic purposes. Furthermore, the invention relates to a novel phenylpropanoid molecule denominated isoteupolioside.Type: GrantFiled: June 19, 2006Date of Patent: April 18, 2017Assignee: I.R.B. ISTITUTO DI RICERCHE BIOTECNOLOGICHE S.r.l.Inventors: Renzo Dal Monte, Roberto Dal Toso, Anacleto Minghetti, Nicoletta Crespi Perellino, Giovanna Pressi
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Patent number: 8709810Abstract: The present invention relates to the preparation of plant cell cultures belonging to the Dendrobium Phalaenopsis, Ansellia, Polyrrhiza, Vanilla, Cattleya and Vanda genera and their use in cosmetic, nutritional and pharmaceutical fields. In particular, the present invention regards a selected cell culture of meristematic cells of plants belonging to the Dendrobium Phalaenopsis, Ansellia, Polyrrhiza, Vanilla, Cattleya and Vanda genera characterized in that it contains an amount of phenylpropanoids greater than 0.1% expressed on the cell dry weight and an amount of hydrosoluble polysaccharides greater than 5% expressed on the cell dry weight, as well as preparations, pharmaceutical and cosmetic compositions or food supplements containing the cell culture.Type: GrantFiled: November 11, 2011Date of Patent: April 29, 2014Assignee: I.R.B. Istituto di Ricerche Biotechnologiche S.r.l.Inventors: Giovanna Pressi, Roberto Dal Toso, Elena Sgaravatti
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Patent number: 8592203Abstract: A process for producing a bioreactor using viable immobilized biological material. The process produces a siliceous layer capable of biomass immobilization and selectively cutting off of macromolecules having a molecular weight higher than a selected threshold. The process includes the steps of: (a) supplying a gas flow of a gas carrier saturated by a mixture of silicon alkoxides selected from the group comprising (1) Si(OR)4, (2) SiH(OR)3, (3) R?Si(OR)3 and (4) R?SiH(OR)2 wherein R and R?, equal or different each other, are alkyl and/or aryl groups, wherein said gas flow is prepared by bubbling the gas carrier into a liquid mixture of said alkoxides in the ratio of (1) 40-85/(2) 0-60/(3) 0-60/(4) 0-60 (% v/v), preferably in the ratio of (1) 40-85/(2) 0-50/(3) 0-50/(4) 0-50 (% v/v), more preferably in the ratio of (1) 50-80/(2) 0-20/(3) 5-30/(4) 5-30 (% v/v), at a temperature of from 20 to 180° C., preferably of from 20 to 100° C.Type: GrantFiled: May 10, 2007Date of Patent: November 26, 2013Assignee: Silbiotec Due S.A.Inventors: Gianni Carturan, Roberto Dal Toso, Renzo Dal Monte
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Publication number: 20130022580Abstract: The present invention relates to the preparation of plant cell cultures belonging to the Dendrobium Phalaenopsis, Anisellia, Polyrrhiza, Vanilla, Cattleya and Vanda genera and their use in cosmetic, nutritional and pharmaceutical fields. In particular, the present invention regards a selected cell culture of meristematic cells of plants belonging to the Dendrobium Phalaenopsis, Anisellia, Polyrrhiza, Vanilla, Cattleya and Vanda genera characterized in that it contains an amount of phenylpropanoids greater than 0.1% expressed on the cell dry weight and an amount of hydrosoluble polysaccharides greater than 5% expressed on the cell dry weight, as well as preparations, pharmaceutical and cosmetic compositions or food supplements containing said cell culture.Type: ApplicationFiled: November 11, 2011Publication date: January 24, 2013Inventors: Giovanna Pressi, Roberto Dal Toso, Elena Sgaravatti
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Publication number: 20110123646Abstract: The present invention refers to the use of extracts from selected and stabilised cell lines comprising phenylpropanoids with high anti-oxidant capacity having a verbascoside titre of between 20% and 90% and a chromophore-free fraction of between 80% and 10%, in human and veterinary medicine, and for nutritional and cosmetic purposes.Type: ApplicationFiled: May 14, 2010Publication date: May 26, 2011Applicant: I.R.B. ISTITUTO DI RICERCHE BIOTECNOLOGICHE S.R.L.Inventors: Renzo Dal Monte, Roberto Dal Toso, Anacleto Minghetti, Nicoletta Crespi Perellino, Giovanna Pressi
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Patent number: 7718199Abstract: The present invention refers to the use of extracts from selected and stabilized cell lines comprising phenylpropanoids with high anti-oxidant capacity having a verbascoside titre of between 20% and 90% and a chromophore-free fraction of between 80% and 10%, in human and veterinary medicine, and for nutritional and cosmetic purposes.Type: GrantFiled: June 19, 2006Date of Patent: May 18, 2010Assignee: I.R.B. Istituto di Ricerche Biotecnologiche S.r.l.Inventors: Renzo Dal Monte, Roberto Dal Toso, Anacleto Minghetti, Nicoletta Crespi Perellino, Giovanna Pressi
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Patent number: 7625883Abstract: Optionally O-substituted glycero-phosphoinositol derivatives, their analogues and their salts wherein the substitutents: R?1, R?2, R2, R3, R4, R5, R6 have the described meaning, their synthesis and their pharmacological effect as modulators of the activation or over-stimulation of cPLA2.Type: GrantFiled: November 7, 2000Date of Patent: December 1, 2009Assignee: I.R.B. Istituto di Ricerche Biotechnologiche S.R.L.Inventors: Daniela Corda, Roberto Dal Toso, Giovanna Bonvento, Gabriele Marcolongo, Renzo Dal Monte
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Publication number: 20070280984Abstract: A process for producing a bioreactor using viable immobilized biological material. The process produces a siliceous layer capable of biomass immobilization and selectively cutting off of macromolecules having a molecular weight higher than a selected threshold. The process includes the steps of: (a) supplying a gas flow of a gas carrier saturated by a mixture of silicon alkoxides selected from the group comprising (1) Si(OR)4, (2) SiH(OR)3, (3) R?Si(OR)3 and (4) R?SiH(OR)2 wherein R and R?, equal or different each other, are alkyl and/or aryl groups, wherein said gas flow is prepared by bubbling the gas carrier into a liquid mixture of said alkoxides in the ratio of (1) 40-85/(2) 0-60/(3) 0-60/(4) 0-60 (% v/v), preferably in the ratio of (1) 40-85/(2) 0-50/(3) 0-50/(4) 0-50 (% v/v), more preferably in the ratio of (1) 50-80/(2) 0-20/(3) 5-30/(4) 5-30 (% v/v), at a temperature of from 20 to 180° C., preferably of from 20 to 100° C.Type: ApplicationFiled: May 10, 2007Publication date: December 6, 2007Inventors: Gianni Carturan, Roberto Dal Toso, Renzo Dal Monte
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Patent number: 7229808Abstract: The present invention relates to a process for producing a bioreactor using viable immobilized biological material and to the bioreactor itself. More particularly, the present invention relates to a process for producing a siliceous layer capable of biomass immobilization and selectively cutting off macromolecules having a molecular weight higher than a selected threshold, comprising the steps of: a) supplying a gas flow of a gas carrier saturated by a mixture of silicon alkoxides selected from the group comprising (1)Si(OR)4, (2)SiH(OR)3, (3)R?Si(OR)3 and (4)R?SiH(OR)2 wherein R and R?, equal or different each other, are alkyl and/or aryl groups, wherein said gas flow is prepared by bubbling the gas carrier into a liquid mixture of said alkoxides in the ratio of (1)40–85/(2)0–60/(3)0–60/(4)0–60 (% v/v), preferably in the ratio of (1)40–85/(2)0–50/(3)0–50/(4)0–50 (% v/v), more preferably in the ratio of (1)50–80/(2)0–20/(3)5–30/(4)5–30 (% v/v), at a temperature of from 20 to 180° C.Type: GrantFiled: January 18, 2002Date of Patent: June 12, 2007Assignee: Silbiotec Due S.A.Inventors: Gianni Carturan, Roberto Dal Toso, Renzo Dal Monte
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Publication number: 20070015262Abstract: The present invention relates to selected and stabilized cell line extracts from Ajuga reptans comprising phenylpropanoids having high antioxidating capacity with a teupolioside titre of between 20% and 90% and a chromophore-free fraction of between 80% and 10%. Said extracts are for use in human and veterinary therapy and for nutritional and cosmetic purposes. Furthermore, the invention relates to a novel phenylpropanoid molecule denominated isoteupolioside.Type: ApplicationFiled: June 19, 2006Publication date: January 18, 2007Applicant: I.R.B. ISTITUTO DI RICERCHE BIOTECNOLOGICHE S.r.l.Inventors: Renzo Dal Monte, Roberto Dal Toso, Anacleto Minghetti, Nicoletta Crespi Perellino, Giovanna Pressi
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Publication number: 20070004011Abstract: The present invention refers to the use of extracts from selected and stabilised cell lines comprising phenylpropanoids with high anti-oxidant capacity having a verbascoside titre of between 20% and 90% and a chromophore-free fraction of between 80% and 10%, in human and veterinary medicine, and for nutritional and cosmetic purposes.Type: ApplicationFiled: June 19, 2006Publication date: January 4, 2007Applicant: I.R.B. ISTITUTO DI RICERCHE BIOTECNOLOGICHE S.r.I.Inventors: Renzo Dal Monte, Roberto Dal Toso, Anacleto Minghetti, Nicoletta Crespi Perellino, Giovanna Pressi
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Publication number: 20050084944Abstract: The present invention relates to a process for producing a bioreactor using viable immobilized biological material and to the bioreactor itself. More particularly, the present invention relates to a process for producing a siliceous layer capable of biomass immobilization and selectively cutting off macromolecules having a molecular weight higher than a selected threshold, comprising the steps of: a) supplying a gas flow of a gas carrier saturated by a mixture of silicon alkoxides selected from the group comprising (1) Si(OR)4, (2) SiH(OR)3, (3) R?Si(OR)3 and (4) R?SiH(OR)2 wherein R and R?, equal or different each other, are alkyl and/or aryl groups, wherein said gas flow is prepared by bubbling the gas carrier into a liquid mixture of said alkoxides in the ratio of (1) 40-85/(2) 0-60/(3) 0-60/(4) 0-60 (% v/v), preferably in the ratio of (1) 40-85/(2) 0-50/(3) 0-50/(4) 0-50 (% v/v), more preferably in the ratio of (1) 50-80/(2) 0-20/(3) 5-30/(4) 5-30 (% v/v), at a temperature of from 20 to 180° C.Type: ApplicationFiled: January 18, 2002Publication date: April 21, 2005Inventors: Gianni Carturan, Roberto Dal Toso, Renzo Dal Monte