Patents by Inventor Roberto Di Santo

Roberto Di Santo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compound with serotoninergic activity, process for preparing it and pharmaceutical composition comprising it
    Patent number: 8686147
    Abstract: Compound of formula (I) in which R1, R2 and R3 are defined in the following description, and the pharmaceutically acceptable acid-addition or base-addition salts thereof. The invention also relates to a process and an intermediate for preparing it, and to a pharmaceutical composition comprising it. The invention also relates to the use of a novel 2H-pyrrolo[3,4-c]quinoline compound for preparing a pharmaceutical composition that is active in the treatment of disturbances of the serotoninergic system.
    Type: Grant
    Filed: July 17, 2009
    Date of Patent: April 1, 2014
    Assignee: Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A.
    Inventors: Maria Alessandra Alisi, Nicola Cazzolla, Roberta Costi, Roberto Di Santo, Guido Furlotti, Angelo Guglielmotti, Lorenzo Polenzani
  • COMPOUND WITH SEROTONINERGIC ACTIVITY, PROCESS FOR PREPARING IT AND PHARMACEUTICAL COMPOSITION COMPRISING IT
    Publication number: 20110160201
    Abstract: Compound of formula (I) in which R1, R2 and R3 are defined in the following description, and the pharmaceutically acceptable acid-addition or base-addition salts thereof. The invention also relates to a process and an intermediate for preparing it, and to a pharmaceutical composition comprising it. The invention also relates to the use of a novel 2H-pyrrolo[3,4-c]quinoline compound for preparing a pharmaceutical composition that is active in the treatment of disturbances of the serotoninergic system.
    Type: Application
    Filed: July 17, 2009
    Publication date: June 30, 2011
    Applicant: AZIENDE CHIMI. RIUN. ANG. FRANC. A.C.R.A.F. S.p.A.
    Inventors: Maria Alessandra Alisi, Nicola Cazzolla, Roberta Costi, Roberto Di Santo, Guido Furlotti, Angelo Guglielmotti, Lorenzo Polenzani
  • Quinolin-4-ones as inhibitors of retroviral integrase for the treatment of HIV, AIDS and AIDS related complex (ARC)
    Patent number: 7776883
    Abstract: Novel quinoline inhibitors of retroviral integrase, particularly HIV-1 integrase. The quinoline inhibitors are oxoquinolines that can be used for preventing or treating AIDS or HIV infection in a subject.
    Type: Grant
    Filed: March 9, 2005
    Date of Patent: August 17, 2010
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Roberto Di Santo, Yves Pommier, Christophe Marchand, Marino Artico, Roberta Costi
  • Naphthyl Derivatives as Inhibitors of Beta-Amyloid Aggregation
    Publication number: 20080255232
    Abstract: Compounds useful in the treatment of disorders characterized by deposits of amyloid aggregates are herein described together with pharmaceutical compounds containing the same. In particular the compounds of the present invention are those having the Formula (I) as reported below, where the radicals have the meaning indicated in the description.
    Type: Application
    Filed: October 12, 2006
    Publication date: October 16, 2008
    Applicant: SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.
    Inventors: Patrizia Minetti, Roberto Di Santo
  • Quinolin-4-Ones as Inhibitors of Retroviral Integrase for the Treatment of Hiv, Aids and Aids Related Complex (Arc)
    Publication number: 20070219242
    Abstract: Novel quinoline inhibitors of retroviral integrase, particularly HIV-1 integrase. The quinoline inhibitors are oxoquinolines that can be used for preventing or treating AIDS or HIV infection in a subject.
    Type: Application
    Filed: March 9, 2005
    Publication date: September 20, 2007
    Inventors: Roberto Di Santo, Yves Pommier, Christophe Marchand, Marino Artico, Roberta Costi