Patents by Inventor Roberto Mariani

Roberto Mariani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220119454
    Abstract: In some embodiments, the present invention provides respiratory syncytial virus (RSV) F proteins, polypeptides and protein complexes that comprise one or more cross-links to stabilize the protein, polypeptide or protein complex in its pre-fusion conformation. In some embodiments the present invention provides RSV F proteins, polypeptides and protein complexes comprising one or more mutations to facilitate such cross-linking. In some embodiments the present invention provides compositions comprising such proteins, polypeptides or protein complexes, including vaccine compositions, and methods of making and using the same.
    Type: Application
    Filed: May 27, 2021
    Publication date: April 21, 2022
    Applicants: CALDER BIOSCIENCES INC., THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC
    Inventors: Christopher Patrick Marshall, Jason Scott McLellan, Peter Joseph Alff, Claudio Bertuccioli, Roberto Mariani
  • Patent number: 11267848
    Abstract: The present invention provides mutant RSV F molecules, such as those that can be, or are stabilized, in a pre-fusion conformation by the introduction of one or more DT cross-links. The present invention also provides methods of making such mutant RSV F molecules, compositions comprising such mutant RSV F molecules, and methods of use of such mutant RSV F molecules, for example in vaccination methods, therapeutic methods, and antibody production methods.
    Type: Grant
    Filed: August 7, 2018
    Date of Patent: March 8, 2022
    Inventors: Christopher Marshall, Mark Yondola, Roberto Mariani, Aaron Zomback, Sonal Gidwani
  • Publication number: 20210327141
    Abstract: A method is described for recording a video. The method comprises receiving one or more user content and then providing a 3D virtual world and a virtual camera having one or more parameters. The optimal 3D flight path of the virtual camera is then determined based on the user content and the virtual camera is then allowed to travel along the optimal 3D flight path and to record the video.
    Type: Application
    Filed: December 2, 2020
    Publication date: October 21, 2021
    Applicant: Skydoor Pte Ltd
    Inventors: Roberto Mariani, Richard Claude Georges Leon Roussel
  • Patent number: 11103099
    Abstract: A beverage dispensing machine designed for aircraft use has compact dimensions, is low-weight and satisfies the safety requirements and standards applicable in that sector. The beverage dispensing machine can dispense both large quantities of a beverage, such as 1.6 liters of American coffee or tea, inside a jug positioned inside an appropriate seat, and smaller quantities of hot water (typically 150 ml), which can be used to prepare beverages, via a nozzle situated on the outside thereof. In one embodiment, the beverage dispensing machine includes a bottom jug retention system having a locking lever hinged on spiral seats to keep the jug stationary during the dispensing of the beverage.
    Type: Grant
    Filed: April 7, 2016
    Date of Patent: August 31, 2021
    Inventors: Lucio Iacobucci, Maurizio Ruspantini, Massimiliano Marcoccia, Roberto Mariani
  • Publication number: 20210261637
    Abstract: Modified FGF-21 polypeptides and uses thereof are provided.
    Type: Application
    Filed: February 2, 2021
    Publication date: August 26, 2021
    Inventors: Thomas P. CUJEC, Roberto MARIANI, Anna-Maria A. HAYS PUTNAM, William M. KEEFE, Nick KNUDSEN, Lillian SKIDMORE, Jason PINKSTAFF, Vadim KRAYNOV
  • Patent number: 10961291
    Abstract: Modified FGF-21 polypeptides and uses thereof are provided.
    Type: Grant
    Filed: June 17, 2019
    Date of Patent: March 30, 2021
    Assignee: AMBRX, INC.
    Inventors: Thomas P. Cujec, Roberto Mariani, Anna-Maria A. Hays Putnam, William M. Keefe, Nick Knudsen, Lillian Skidmore, Jason Pinkstaff, Vadim Kraynov
  • Publication number: 20200361997
    Abstract: The present invention provides mutant RSV F molecules, such as those that can be, or are stabilized, in a pre-fusion conformation by the introduction of one or more DT cross-links. The present invention also provides methods of making such mutant RSV F molecules, compositions comprising such mutant RSV F molecules, and methods of use of such mutant RSV F molecules, for example in vaccination methods, therapeutic methods, and antibody production methods.
    Type: Application
    Filed: August 7, 2018
    Publication date: November 19, 2020
    Inventors: Christopher Marshall, Mark Yondola, Roberto Mariani, Aaron Zomback, Sonal Gidwani
  • Patent number: 10772462
    Abstract: The present invention relates to a water heating system (part number lacubucci HF Aerospace AS0012480) for beverage dispensing machines. The heater has a double system: a pre-chamber, preferably of the spirally wound type, for pre-heating the water along a predefined path, and a chamber which is always full of water heated with resistors making direct contact with the water (or in some cases with a protection jacket) for maximizing the efficiency.
    Type: Grant
    Filed: April 7, 2016
    Date of Patent: September 15, 2020
    Inventors: Lucio Iacobucci, Maurizio Ruspantini, Massimiliano Marcoccia, Roberto Mariani
  • Publication number: 20200175762
    Abstract: A method is described for recording a video. The method comprises receiving one or more user content and then providing a 3D virtual world and a virtual camera having one or more parameters. The optimal 3D flight path of the virtual camera is then determined based on the user content and the virtual camera is then allowed to travel along the optimal 3D flight path and to record the video.
    Type: Application
    Filed: August 6, 2019
    Publication date: June 4, 2020
    Applicant: Skydoor Pte Ltd
    Inventors: Roberto Mariani, Richard Claude Georges Leon Roussel
  • Publication number: 20200031894
    Abstract: Modified FGF-21 polypeptides and uses thereof are provided.
    Type: Application
    Filed: June 17, 2019
    Publication date: January 30, 2020
    Inventors: Thomas P. CUJEC, Roberto MARIANI, Anna-Maria A. HAYS PUTNAM, William M. KEEFE, Nick KNUDSEN, Lillian SKIDMORE, Jason PINKSTAFF, Vadim KRAYNOV
  • Publication number: 20190292228
    Abstract: In some embodiments, the present invention provides respiratory syncytial virus (RSV) F proteins, polypeptides and protein complexes that comprise one or more cross-links to stabilize the protein, polypeptide or protein complex in its pre-fusion conformation. In some embodiments the present invention provides RSV F proteins, polypeptides and protein complexes comprising one or more mutations to facilitate such cross-linking. In some embodiments the present invention provides compositions comprising such proteins, polypeptides or protein complexes, including vaccine compositions, and methods of making and using the same.
    Type: Application
    Filed: October 9, 2018
    Publication date: September 26, 2019
    Applicants: CALDER BIOSCIENCES INC., THE UNITED STATES OF AMERICA, AS REPRESENTED BY SECRETARY, DEPARTMENT OF HELATH
    Inventors: Christopher Patrick Marshall, Jason Scott McLellan, Peter Joseph Alff, Claudio Bertuccioli, Roberto Mariani
  • Patent number: 10377805
    Abstract: Modified FGF-21 polypeptides and uses thereof are provided.
    Type: Grant
    Filed: April 13, 2018
    Date of Patent: August 13, 2019
    Assignee: AMBRX, INC.
    Inventors: Thomas P. Cujec, Roberto Mariani, Anna-Maria A. Hays Putnam, William M. Keefe, Nick Knudsen, Lillian Skidmore, Jason Pinkstaff, Vadim Kraynov
  • Patent number: 10373376
    Abstract: A method is described for recording a video. The method comprises receiving one or more user content and then providing a 3D virtual world and a virtual camera having one or more parameters. The optimal 3D flight path of the virtual camera is then determined based on the user content and the virtual camera is then allowed to travel along the optimal 3D flight path and to record the video.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: August 6, 2019
    Assignee: SKYDOOR PTE LTD
    Inventors: Roberto Mariani, Richard Claude Georges Leon Roussel
  • Patent number: 10125172
    Abstract: In some embodiments, the present invention provides respiratory syncytial virus (RSV) F proteins, polypeptides and protein complexes that comprise one or more cross-links to stabilize the protein, polypeptide or protein complex in its pre-fusion conformation. In some embodiments the present invention provides RSV F proteins, polypeptides and protein complexes comprising one or more mutations to facilitate such cross-linking. In some embodiments the present invention provides compositions comprising such proteins, polypeptides or protein complexes, including vaccine compositions, and methods of making and using the same.
    Type: Grant
    Filed: July 24, 2014
    Date of Patent: November 13, 2018
    Assignees: CALDER BIOSCIENCES INC., THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services
    Inventors: Christopher Patrick Marshall, Jason Scott McLellan, Peter Joseph Alff, Claudio Bertuccioli, Roberto Mariani
  • Publication number: 20180298073
    Abstract: Modified FGF-21 polypeptides and uses thereof are provided.
    Type: Application
    Filed: April 13, 2018
    Publication date: October 18, 2018
    Inventors: Thomas P. CUJEC, Roberto MARIANI, Anna-Maria A. HAYS PUTNAM, William M. KEEFE, Nick KNUDSEN, Lillian SKIDMORE, Jason PINKSTAFF, Vadim KRAYNOV
  • Patent number: 9975936
    Abstract: Modified FGF-21 polypeptides and uses thereof are provided.
    Type: Grant
    Filed: October 13, 2016
    Date of Patent: May 22, 2018
    Assignee: AMBRX, INC.
    Inventors: Thomas P. Cujec, Roberto Mariani, Anna-Maria A. Hays Putnam, William M. Keefe, Nick Knudsen, Lillian Skidmore, Jason Pinkstaff, Vadim Kraynov
  • Publication number: 20180078085
    Abstract: The present invention relates to a water heating system (part number lacubucci HF Aerospace AS0012480) for beverage dispensing machines. The heater has a double system: a pre-chamber, preferably of the spirally wound type, for pre-heating the water along a predefined path, and a chamber which is always full of water heated with resistors making direct contact with the water (or in some cases with a protection jacket) for maximizing the efficiency.
    Type: Application
    Filed: April 7, 2016
    Publication date: March 22, 2018
    Inventors: Lucio Iacobucci, Maurizio Ruspantini, Massimiliano Marcoccia, Roberto Mariani
  • Publication number: 20180064282
    Abstract: A beverage dispensing machine designed for aircraft use has compact dimensions, is low-weight and satisfies the safety requirements and standards applicable in that sector. The beverage dispensing machine can dispense both large quantities of a beverage, such as 1.6 liters of American coffee or tea, inside a jug positioned inside an appropriate seat, and smaller quantities of hot water (typically 150 ml), which can be used to prepare beverages, via a nozzle situated on the outside thereof. In one embodiment, the beverage dispensing machine includes a bottom jug retention system having a locking lever hinged on spiral seats to keep the jug stationary during the dispensing of the beverage.
    Type: Application
    Filed: April 7, 2016
    Publication date: March 8, 2018
    Inventors: Lucio Iacobucci, Maurizio Ruspantini, Massimiliano Marcoccia, Roberto Mariani
  • Publication number: 20170096463
    Abstract: Modified FGF-21 polypeptides and uses thereof are provided.
    Type: Application
    Filed: October 13, 2016
    Publication date: April 6, 2017
    Inventors: Thomas P. CUJEC, Roberto Mariani, Anna-Maria A. Hays Putnam, Wiliam M. Keefe, Nick Knudsen, Lillian Skidmore, Jason Pinkstaff, Vadim Kraynov
  • Patent number: 9517273
    Abstract: Modified FGF-21 polypeptides and uses thereof are provided.
    Type: Grant
    Filed: April 7, 2015
    Date of Patent: December 13, 2016
    Assignee: AMBRX, INC.
    Inventors: Thomas P. Cujec, Roberto Mariani, Anna-Maria A. Hays Putnam, Wiliam M. Keefe, Nick Knudsen, Lillian Skidmore, Jason Pinkstaff, Vadim Kraynov