Patents by Inventor Roberto Montesano

Roberto Montesano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic and diagnostic methods and compositions based on Jagged/Notch proteins and nucleic acids
    Patent number: 6825007
    Abstract: This invention relates to therapeutic and diagnostic methods and compositions based on Jagged/Notch proteins and nucleic acids, and on the role of their signaling pathway in endothelial cell migration and/or differentiation. In addition, this invention provides a substantially purified Jagged protein, as well as a substantially purified nucleic acid molecule or segment thereof encoding Jagged protein, or a functionally equivalent derivative, or allelic or species variant thereof.
    Type: Grant
    Filed: August 6, 2002
    Date of Patent: November 30, 2004
    Assignee: Maine Medical Center Research Institute
    Inventors: Ann B. Zimrin, Thomas Maciag, Michael S. Pepper, Roberto Montesano, Michael Wong
  • Therapeutic and diagnostic methods and compositions based on Jagged/Notch proteins and nucleic acids
    Publication number: 20030083465
    Abstract: This invention relates to therapeutic and diagnostic methods and compositions based on Jagged/Notch proteins and nucleic acids, and on the role of their signaling pathway in endothelial cell migration and/or differentiation. In addition, this invention provides a substantially purified Jagged protein, as well as a substantially purified nucleic acid molecule or segment thereof encoding Jagged protein, or a functionally equivalent derivative, or allelic or species variant thereof.
    Type: Application
    Filed: August 6, 2002
    Publication date: May 1, 2003
    Applicant: Maine Medical Center Research Institute
    Inventors: Ann B. Zimrin, Thomas MaCiag, Michael S. Pepper, Roberto Montesano, Michael Wong
  • Therapeutic and diagnostic methods and compositions based on jagged/notch proteins and nucleic acids
    Patent number: 6433138
    Abstract: This invention relates to therapeutic and diagnostic methods and compositions based on Jagged/Notch proteins and nucleic acids, and on the role of their signaling pathway in endothelial cell migration and/or differentiation. In addition, this invention provides a substantially purified Jagged protein, as well as a substantially purified nucleic acid molecule or segment thereof encoding Jagged protein, or a functionally equivalent derivative, or allelic or species variant thereof.
    Type: Grant
    Filed: November 25, 1998
    Date of Patent: August 13, 2002
    Assignee: Maine Medical Center Research Institute
    Inventors: Ann B. Zimrin, Michael Wong, Thomas Maciag, Michael S. Pepper, Roberto Montesano