Patents by Inventor Roberto Ognibene

Roberto Ognibene has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Direct injection moldable and rapidly disintegrating tablet matrix
    Patent number: 11166917
    Abstract: The present invention relates to a novel directly compressible matrix for the production of tablets which disintegrate rapidly in the presence of moisture, in particular in the mouth.
    Type: Grant
    Filed: May 25, 2009
    Date of Patent: November 9, 2021
    Assignee: Merck Patent GmbH
    Inventors: Daniela Kleinwaechter, Guenter Moddelmog, Roberto Ognibene
  • Pulverulent, directly compressible polyvinyl alcohol grades
    Patent number: 11040012
    Abstract: The present invention relates to premixes for the production of active compound-containing tablets which comprise polyvinyl alcohols (PVAs). The invention also relates to active compound-containing tablets which comprise a corresponding premix.
    Type: Grant
    Filed: July 3, 2015
    Date of Patent: June 22, 2021
    Assignee: Merck Patent GmbH
    Inventors: Roberto Ognibene, Finn Bauer, Thorsten Wedel, Guenter Moddelmog
  • Formulation having controlled, delayed release of active ingredient
    Patent number: 10874615
    Abstract: The present invention relates to novel pharmaceutical formulations which have controlled, delayed release of active ingredient, and to a process for the preparation of such formulations. The invention additionally relates to the use of these novel pharmaceutical administration forms as medicaments for the treatment of diseases which require delayed release of the active ingredient, such as hypertension, or asthmatic diseases.
    Type: Grant
    Filed: August 25, 2016
    Date of Patent: December 29, 2020
    Assignee: Merck Patent GmbH
    Inventors: Finn Bauer, Thorsten Wedel, Guenter Moddelmog, Gudrun Birk, Roberto Ognibene, Dieter Lubda
  • Directly compressible composition comprising microcrystalline cellulose
    Patent number: 10828258
    Abstract: The present invention relates to a directly compressible composition for the production of tablets which comprise fine-grained polyvinyl alcohols (PVAs) and fine-grained microcrystalline celluloses (MCCs) in a co-mixture. The present invention also relates to the use of this mixture and to a process for the preparation thereof.
    Type: Grant
    Filed: July 11, 2018
    Date of Patent: November 10, 2020
    Assignee: Merck Patent GmbH
    Inventors: Roberto Ognibene, Finn Bauer, Thorsten Wedel, Guenter Moddelmog
  • FORMULATION HAVING CONTROLLED, DELAYED RELEASE OF ACTIVE INGREDIENT
    Publication number: 20200246270
    Abstract: The present invention relates to novel pharmaceutical formulations which have controlled, delayed release of active ingredient, and to a process for the preparation of such formulations. The invention additionally relates to the use of these novel pharmaceutical administration forms as medicaments for the treatment of diseases which require delayed release of the active ingredient, such as hypertension, or asthmatic diseases.
    Type: Application
    Filed: April 21, 2020
    Publication date: August 6, 2020
    Applicant: Merck Patent GmbH
    Inventors: Finn BAUER, Thorsten WEDEL, Guenter MODDELMOG, Gudrun BIRK, Roberto OGNIBENE, Dieter LUBDA
  • Directly compressible composition comprising microcrystalline cellulose
    Publication number: 20200214984
    Abstract: The present invention relates to a directly compressible composition for the production of tablets which comprise fine-grained polyvinyl alcohols (PVAs) and fine-grained microcrystalline celluloses (MCCs) in a co-mixture. The present invention also relates to the use of this mixture and to a process for the preparation thereof.
    Type: Application
    Filed: March 17, 2020
    Publication date: July 9, 2020
    Applicant: Merck Patent GmbH
    Inventors: Roberto OGNIBENE, Finn BAUER, Thorsten WEDEL, Guenter MODDELMOG
  • FORMULATION HAVING CONTROLLED, DELAYED RELEASE OF ACTIVE INGREDIENT
    Publication number: 20190038562
    Abstract: The present invention relates to novel pharmaceutical formulations which have controlled, delayed release of active ingredient, and to a process for the preparation of such formulations. The invention additionally relates to the use of these novel pharmaceutical administration forms as medicaments for the treatment of diseases which require delayed release of the active ingredient, such as hypertension, or asthmatic diseases.
    Type: Application
    Filed: August 25, 2016
    Publication date: February 7, 2019
    Applicant: Merck Patent GmbH
    Inventors: Finn BAUER, Thorsten WEDEL, Guenter MODDELMOG, Gudrun BIRK, Roberto OGNIBENE, Dieter LUBDA
  • Directly compressible composition comprising microcrystalline cellulose
    Publication number: 20180318224
    Abstract: The present invention relates to a directly compressible composition for the production of tablets which comprise fine-grained polyvinyl alcohols (PVAs) and fine-grained microcrystalline celluloses (MCCs) in a co-mixture. The present invention also relates to the use of this mixture and to a process for the preparation thereof.
    Type: Application
    Filed: July 11, 2018
    Publication date: November 8, 2018
    Applicant: Merck Patent GmbH
    Inventors: Roberto OGNIBENE, Finn BAUER, Thorsten WEDEL, Guenter MODDELMOG
  • TABLETS HAVING MEDIA INDEPENDENT ACTIVE SUBSTANCE DELIVERY
    Publication number: 20180250233
    Abstract: The present invention relates to formulations having extended release of active ingredient, comprising an active ingredient from BCS Class I having high solubility and high permeability in a polyvinyl alcohol-containing matrix, from which the active ingredient is released at a controlled rate over a therapeutically relevant time period independently of the composition of the release medium.
    Type: Application
    Filed: August 25, 2016
    Publication date: September 6, 2018
    Applicant: MERCK PATENT GMBH
    Inventors: Finn BAUER, Thorsten WEDEL, Gudrun BIRK, Roberto OGNIBENE, Dieter LUBDA, Guenter MODDELMOG
  • PULVERULENT, DIRECTLY COMPRESSIBLE POLYVINYL ALCOHOL GRADES
    Publication number: 20180207101
    Abstract: The present invention relates to premixes for the production of active compound-containing tablets which comprise polyvinyl alcohols (PVAs). The invention also relates to active compound-containing tablets which comprise a corresponding premix.
    Type: Application
    Filed: July 3, 2015
    Publication date: July 26, 2018
    Applicant: Merck Patent GmbH
    Inventors: Roberto OGNIBENE, Finn BAUER, Thorsten WEDEL, Guenter MODDELMOG
  • DIRECTLY COMPRESSIBLE POLYVINYL ALCOHOLS
    Publication number: 20170216213
    Abstract: The present invention relates to directly compressible co-mixtures for the production of tablets having delayed release of active compound which comprise polyvinyl alcohols (PVAs) and microcrystalline celluloses (MCCs).
    Type: Application
    Filed: July 3, 2015
    Publication date: August 3, 2017
    Applicant: Merck Patent GmbH
    Inventors: Roberto OGNIBENE, Finn BAUER, Thorsten WEDEL, Guenter MODDELMOG
  • Directly compressible composition comprising microcrystalline cellulose
    Publication number: 20170209380
    Abstract: The present invention relates to a directly compressible composition for the production of tablets which comprise fine-grained polyvinyl alcohols (PVAs) and fine-grained microcrystalline celluloses (MCCs) in a co-mixture. The present invention also relates to the use of this mixture and to a process for the preparation thereof.
    Type: Application
    Filed: July 3, 2015
    Publication date: July 27, 2017
    Applicant: Merck Patent GmbH
    Inventors: Roberto OGNIBENE, Finn BAUER, Thorsten WEDEL, Guenter MODDELMOG
  • Magnesium hydroxide carbonate as excipient in pharmaceutical preparations having improved release of active ingredient
    Publication number: 20150328316
    Abstract: The present invention relates to pharmaceutical formulations of active ingredients which have low solubility in aqueous solutions, having improved release of active ingredient, and to a process for the preparation thereof. In particular, these are pharmaceutical preparations in which magnesium hydroxide carbonate serves as excipient.
    Type: Application
    Filed: November 22, 2013
    Publication date: November 19, 2015
    Applicant: MERCK PATENT GMBH
    Inventors: Guenter MODDELMOG, Roberto OGNIBENE, Thorsten WEDEL, Dieter LUBDA
  • MAGNESIUM HYDROXIDE CARBONATE AS CARRIER MATERIAL IN ACTIVE INGREDIENT-CONTAINING PREPARATIONS
    Publication number: 20150273062
    Abstract: The present invention relates to solid formulations which contain at least one porous carrier and one or more functional substances in a stable mixture, and to the use thereof.
    Type: Application
    Filed: August 19, 2013
    Publication date: October 1, 2015
    Applicant: Merck Patent GmbH
    Inventors: Guenter Moddelmog, Roberto Ognibene, Thorsten Wedel, Dieter Lubda
  • COATED TABLETS AND THE PRODUCTION THEREOF
    Publication number: 20150104512
    Abstract: The present invention provides a rapidly disintegrating pharmaceutical formulation in the form of a coated tablet having increased mechanical strength, or hardness. The invention furthermore relates to a process for the production of the coated tablet and to the use of these formulations.
    Type: Application
    Filed: April 2, 2013
    Publication date: April 16, 2015
    Applicant: Merck Patent GmbH
    Inventors: Roberto Ognibene, Sandra Erika Bernhardt, Melanie Mechthild Breidung, Dieter Lubda, Hans-Leonhard Ohrem
  • Direct Injection moldable and rapidly disintegrating tablet matrix
    Publication number: 20110091545
    Abstract: The present invention relates to a novel directly compressible matrix for the production of tablets which disintegrate rapidly in the presence of moisture, in particular in the mouth.
    Type: Application
    Filed: May 25, 2009
    Publication date: April 21, 2011
    Inventors: Daniela Kleinwaechter, Guenter Moddelmog, Roberto Ognibene