Patents by Inventor Roberto Osellame

Roberto Osellame has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11027045
    Abstract: The present invention relates to a supermatrix of synthetic niches comprising at least two matrices of niches wherein each matrix comprises n×m niches and wherein the distance (d) between a matrix and the other is greater than zero and wherein in each matrix every synthetic niche has one or more walls in common with the others synthetic niches of the matrix. A support for the culture of cells that includes at least one supermatrix and the use of said supermatrix or support for the in vitro culture of cells, in particular stem cells, or for the in vivo implant in a subject in order to promote tissue or organ regeneration through cell repopulation are also within the scope of the present invention.
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: June 8, 2021
    Assignees: POLITECNICO DI MILANO, CONSIGLIO NAZIONALE DELLE RICERCHE, FONDAZIONE CARIPLO
    Inventors: Manuela Teresa Raimondi, Giulio Cerullo, Roberto Osellame, Andrea Remuzzi
  • Publication number: 20200337824
    Abstract: An implantable medical device obtained by means of two-photon laser polymerisation of a resin to form a three-dimensional matrix, wherein: said three-dimensional matrix comprises a number of levels distributed in height; and said three-dimensional matrix comprises reference means designed to uniquely identify the height of each level from a pre-set reference, by means of a multi-photon fluorescence-excitation microscope; said implantable medical device being characterised in that said reference means comprise a solid having a cross section that varies with height.
    Type: Application
    Filed: December 18, 2018
    Publication date: October 29, 2020
    Inventors: Manuela Teresa Raimondi, Giulio Cerullo, Claudio Conci, Tommaso Zandrini, Roberto Osellame, Giuseppe Chirico
  • Publication number: 20200046881
    Abstract: The present invention relates to a supermatrix of synthetic niches comprising at least two matrices of niches wherein each matrix comprises n×m niches and wherein the distance (d) between a matrix and the other is greater than zero and wherein in each matrix every synthetic niche has one or more walls in common with the others synthetic niches of the matrix. A support for the culture of cells that includes at least one supermatrix and the use of said supermatrix or support for the in vitro culture of cells, in particular stem cells, or for the in vivo implant in a subject in order to promote tissue or organ regeneration through cell repopulation are also within the scope of the present invention.
    Type: Application
    Filed: August 31, 2016
    Publication date: February 13, 2020
    Inventors: Manuela Teresa RAIMONDI, Giulio CERULLO, Roberto OSELLAME, Andrea REMUZZI
  • Patent number: 10520425
    Abstract: An integrated optofluidic device to illuminate, along an irradiation direction, a fluidic sample containing an object to be analysed, the device comprising: a substrate comprising an entry surface and being made of a material transparent to a light beam incident through the entry surface along the irradiation direction; a microfluidic channel formed in the substrate and having a channel portion intercepting the irradiation direction and extending along a longitudinal axis transverse to the irradiation direction, the microfluidic channel comprising a first flow inlet port for loading a fluidic sample therein, and an elongated lens cavity for an optofluidic cylindrical lens, the cavity being formed in the substrate and being arranged along the beam irradiation direction between the entry surface and the microfluidic channel, wherein the lens cavity is in fluid communication with a lens inlet port for loading a lens fluid.
    Type: Grant
    Filed: September 27, 2016
    Date of Patent: December 31, 2019
    Assignees: POLITECNICO DI MILANO, CONSIGLIO NAZIONALE DELLE RICERCHE-CNR
    Inventors: Andrea Bassi, Petra Paiè, Roberto Osellame, Francesca Bragheri
  • Publication number: 20180275045
    Abstract: An integrated optofluidic device to illuminate, along an irradiation direction, a fluidic sample containing an object to be analysed, the device comprising: a substrate comprising an entry surface and being made of a material transparent to a light beam incident through the entry surface along the irradiation direction; a microfluidic channel formed in the substrate and having a channel portion intercepting the irradiation direction and extending along a longitudinal axis transverse to the irradiation direction, the microfluidic channel comprising a first flow inlet port for loading a fluidic sample therein, and an elongated lens cavity for an optofluidic cylindrical lens, the cavity being formed in the substrate and being arranged along the beam irradiation direction between the entry surface and the microfluidic channel, wherein the lens cavity is in fluid communication with a lens inlet port for loading a lens fluid.
    Type: Application
    Filed: September 27, 2016
    Publication date: September 27, 2018
    Applicants: POLITECNICO DI MILANO, CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Andrea Bassi, Petra Paiè, Roberto Osellame, Francesca Bragheri
  • Patent number: 9488778
    Abstract: A method for realizing an optical waveguide in a substrate by means of a femtosecond laser system, the waveguide including a birefringence axis tilted by a predetermined angle for at least a segment, is disclosed. The method includes preparing a substrate including a free surface, focusing a femtosecond laser beam into the substrate, in order to induce a refractive index modification of a volume of such substrate around the focal region. The method further includes varying a propagation direction of the femtosecond laser beam to reach a propagation direction describing a predetermined non-vanishing angle with respect to the normal to the free surface of the substrate, and translating the focal region with respect to the substrate, in order to generate the waveguide segment.
    Type: Grant
    Filed: April 18, 2014
    Date of Patent: November 8, 2016
    Assignees: CONSIGLIO NAZIONALE DELLE RICERCHE, SAPIENZA UNIVERSITA' DI ROMA
    Inventors: Roberto Osellame, Andrea Crespi, Giacomo Corrielli, Fabio Sciarrino
  • Publication number: 20160054522
    Abstract: A method for realizing an optical waveguide in a substrate by means of a femtosecond laser system, the waveguide including a birefringence axis tilted by a predetermined angle for at least a segment, is disclosed. The method includes preparing a substrate including a free surface, focusing a femtosecond laser beam into the substrate, in order to induce a refractive index modification of a volume of such substrate around the focal region. The method further includes varying a propagation direction of the femtosecond laser beam to reach a propagation direction describing a predetermined non-vanishing angle with respect to the normal to the free surface of the substrate, and translating the focal region with respect to the substrate, in order to generate the waveguide segment.
    Type: Application
    Filed: April 18, 2014
    Publication date: February 25, 2016
    Applicants: SAPIENZA UNIVERSITA' DI ROMA, CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Roberto OSELLAME, Andrea CRESPI, Giacomo CORRIELLI, Fabio SCIARRINO
  • Publication number: 20140126030
    Abstract: A quantum logic gate for qubits, suitable for receiving as inputs at least two polarization-encoded qubits, includes at least one partially polarizing beam splitter (PPBS), the beam splitter comprising a first waveguide and a second waveguide which are constructed in integrated optics, the first and second waveguides having a refractive index contrast of between 0.1% and 6% and a birefringence of between 10?6 and 6*10?5.
    Type: Application
    Filed: May 3, 2012
    Publication date: May 8, 2014
    Applicants: UNIVERSITA' DEGLI STUDI DI ROMA LA SAPIENZA, CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Andrea Crespi, Paolo Mataloni, Roberta Ramponi, Linda Sansoni, Fabio Sciarrino, Giuseppe Vallone, Roberto Osellame
  • Patent number: 7215856
    Abstract: A reconfigurable optical device for wavelength-division multiplexing networks, comprising two waveguides (A, B) parallel to each other, with two-dimensional confinement, coupled by a bi-directional coupler (C), suitable to selectively drop one and only one of the channels composing the Wavelength-Division multiplexing signal (WDM); the device is reconfigurable as, by appropriately varying the wavelength of the combined pumping beam inside a first waveguide (A), any channel forming the WDM signal can be dropped.
    Type: Grant
    Filed: March 13, 2002
    Date of Patent: May 8, 2007
    Assignee: Politecnico Di Milano
    Inventors: Roberto Osellame, Roberta Ramponi, Marco Marangoni
  • Publication number: 20050047712
    Abstract: A reconfigurable optical device for wavelength-division multiplexing networks, comprising two waveguides (A, B) parallel to each other, with two-dimensional confinement, coupled by a bi-directional coupler (C), suitable to selectively drop one and only one of the channels composing the Wavelength-Division multiplexing signal (WDM); the device is reconfigurable as, by appropriately varying the wavelength of the combined pumping beam inside a first waveguide (A), any channel forming the WDM signal can be dropped.
    Type: Application
    Filed: March 13, 2002
    Publication date: March 3, 2005
    Inventors: Roberto Osellame, Roberta Ramponi, Marco Marangoni