Patents by Inventor Roberto PIERINI

Roberto PIERINI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTIC VACCINE FOR TREATING OR PREVENTING MERKEL CELL POLYOMA VIRUS-ASSOCIATED TUMORS
    Publication number: 20180201940
    Abstract: The invention relates to a therapeutic vaccine useful against tumors exhibiting as signature the Large T antigen (LT) of the Merkel Cell PolyomaVirus (MCPyV). Additionally, the therapeutic vaccine may be also useful for preventing tumors in healthy individuals infected with MCPyV. The therapeutic vaccine involves a type-3 secretion system (T3SS) bacterial vector able to deliver a polypeptide comprising LT epitopes to antigen presenting cells (APCs), such as a truncated form of LT. The invention also relates to a fusion protein comprising a truncated form of LT.
    Type: Application
    Filed: June 2, 2016
    Publication date: July 19, 2018
    Inventors: Laurent BUFFAT, Roberto PIERINI