Patents by Inventor Roberto Simone

Roberto Simone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MEANS FOR MODULATING GENE EXPRESSION
    Publication number: 20190314398
    Abstract: The present invention provides vectors for delivering to a cell, or expressing in a cell, a therapeutic RNA that is capable of reducing expression of a target gene. Compositions comprising the vectors and comprising the therapeutic RNAs are also provided, as are methods for their use.
    Type: Application
    Filed: May 19, 2017
    Publication date: October 17, 2019
    Inventors: Roberto SIMONE, Rohan DE SILVA
  • Method of manufacturing a mixture of amplified double-stranded nucleic acids comprising unknown sequence
    Patent number: 9249457
    Abstract: The purpose of the subject invention is to provide a method of manufacturing a mixture of amplified double-stranded nucleic acids comprising unknown sequence including the complete 5? end sequence. A method of manufacturing a mixture of amplified double-stranded nucleic acids comprising: (a) preparing a single-stranded nucleic acid comprising a single-stranded adapter 1, a single-stranded nucleic acid fragment and a single-stranded adapter 2, and (b) conducting PCR with said single-stranded nucleic acid prepared in step (a), a primer 1, and a primer 2 to amplify double-stranded nucleic acids.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: February 2, 2016
    Assignee: Riken
    Inventors: Piero Carninci, Charles Plessy, Roberto Simone
  • Method of Manufacturing a Mixture of Amplified Double-Stranded Nucleic Acids Comprising Unknown Sequence
    Publication number: 20110159505
    Abstract: The purpose of the subject invention is to provide a method of manufacturing a mixture of amplified double-stranded nucleic acids comprising unknown sequence including the complete 5? end sequence, A method of manufacturing a mixture of amplified double-stranded nucleic acids comprising: (a) preparing a single-stranded nucleic acid comprising a single-stranded adapter 1, a single-stranded nucleic acid fragment and a single-stranded adapter 2, and (b) conducting PCR with said single-stranded nucleic acid prepared in step (a), a primer 1, and a primer 2 to amplify double-stranded nucleic acids.
    Type: Application
    Filed: June 18, 2009
    Publication date: June 30, 2011
    Applicant: Riken
    Inventors: Piero Carnichi, Charles Plessy, Roberto Simone