Abstract: The present invention provides for eyeglasses to deliver light therapy to the wearer. The eyeglass lenses or frames feature an embedded light source in logical and electrical communication with power, sensors, processors, and other components contained within the eyeglasses.

Abstract: This invention discloses methods and apparatus for providing an ophthalmic lens with light source capable of providing specific bandwidths of light to an eye of a wearer. In some embodiments, an ophthalmic lens is cast molded from a silicone hydrogel and an energy source and light source encapsulated within the ophthalmic lens.

Abstract: The present invention provides for eyeglasses used together with contact lenses to deliver light therapy to the wearer. The eyeglass lenses or frames feature an embedded light source in logical and electrical communication with power, sensors, processors, and other components contained within the eyeglasses. The eyeglass lenses or frames project light into complimentary contact lenses which refract, diffract or reflect light into the wearer's eyes.

Abstract: The present invention provides for eyeglasses used together with contact lenses to deliver light therapy to the wearer. The eyeglass lenses or frames feature an embedded light source in logical and electrical communication with power, sensors, processors, and other components contained within the eyeglasses. The eyeglass lenses or frames project light into complimentary contact lenses which refract, diffract or reflect light into the wearer's eyes.

Abstract: The present invention provides for eyeglasses to deliver light therapy to the wearer. The eyeglass lenses or frames feature an embedded light source in logical and electrical communication with power, sensors, processors, and other components contained within the eyeglasses.

Abstract: The present invention provides for eyeglasses used together with contact lenses to deliver light therapy to the wearer. The eyeglass lenses or frames feature an embedded light source in logical and electrical communication with power, sensors, processors, and other components contained within the eyeglasses. The eyeglass lenses or frames project light into complimentary contact lenses which refract, diffract or reflect light into the wearer's eyes.

Abstract: The present invention provides for eyeglasses to deliver light therapy to the wearer. The eyeglass lenses or frames feature an embedded light source in logical and electrical communication with power, sensors, processors, and other components contained within the eyeglasses.

Abstract: This invention discloses methods and apparatus for providing an ophthalmic lens with light source capable of providing specific bandwidths of light to an eye of a wearer. In some embodiments, an ophthalmic lens is cast molded from a silicone hydrogel and an energy source and light source encapsulated within the ophthalmic lens.

Abstract: Chelating agents, in particular dipyridoxyl and aminopolycarboxylic acid based chelating agents, and their metal chelates, when linked directly or indirectly to at least one nitric oxide releasing moiety, or when use in combination with nitric oxide or a nitric oxide releasing moiety have been found to be effective in treating a variety of disorders. In particular, such compounds may be used in treating conditions associated with the presence of free radicals in the body, e.g. reperfusion injuries, and in reducing the cardiotoxicity of anti-tumor agents, e.g. anthracyclines and/or paclitaxel.

Abstract: Novel thienopyran compounds are disclosed, useful as anti-hypertensive agents and for asthma treatment. One group of the compounds has a heterocyclic ring spiro-connected at the 7-position of the thienopyran ring structure. Use of thienopyran compounds in hair growth modulation is described.

Abstract: The invention provides the use of dipyridoxyl or aminopolycarboxylic acid based chelating agents, metal chelates and salts thereof, in the manufacture of a therapeutic agent for use in the treatment or prophylaxis of atherosclerosis and related conditions in the human or non-human animal body.

Abstract: The invention provides the use of a compound of formula (I) or a metal chelate or salt thereof in the manufacture of a therapeutic agent for use in the treatment of prophylaxis of conditions resulting from the presence of free radicals in the human or non-human animal body (wherein in formula (I): each R1 independently represents hydrogen or —CH2COR5; R5 represents hydroxy, optionally hydroxylated alkoxy, amino or alkylamido; each R2 independently represents a group XYR6; X represents a bond, or a C1-3 alkylene or oxoalkylene group optionally substituted by a group R7; Y represents a bond, an oxygen atom or a group NR6; R6 is a hydrogen atom, a group COOR8, an alkyl, alkenyl, cycloalkyl, aryl or aralkyl group optionally substituted by one or more groups selected from COOR8, CONR82, NR82, OR8, ═NR8, ═O, OP(O)(OR8)R7 and OSO3M; R7 is hydroxy, an optionally hydroxylated, optionally alkoxylated alkyl or aminoalkyl group; R8 is a hydrogen atom or an optionally hydroxylated, optionally alkoxylated a

Abstract: The invention relates to the use of certain chelating agents and their metal chelates and to the use of certain manganese containing compounds, in particular manganese chelates, in the manufacture of a therapeutic agent for use in reducing the cardiotoxicity of an antitumor agent. Such compounds are particularly effective in reducing the side-effects of anthracycline drugs and/or paclitaxel.

Abstract: The invention relates to heterocyclic amides of the formula ##STR1## in which the radicals A, Z, A.sub.1, R.sub.1, R.sub.2 and R.sub.3 are as defined in the description, to a process for the preparation of these amides and to their use as active substances for the curing and amelioration of disorders and diseases which can be treated by exerting influence on potassium channels.

Abstract: The invention relates to optically active 1,4-dihydropyridine compounds of Formulas Ia and Ib as defined hereinabove which are effective for influencing circulation. Also included in the invention are compositions containing said optically active compounds and methods for the use of said compounds and compositions.

Abstract: The invention relates to optically active 1,4-dihydropyridine compounds of Formulas Ia and Ib as defined hereinabove which are effective for influencing circulation. Also included in the invention are compositions containing said optically active compounds and methods for the use of said compounds and compositions.

Abstract: A method of treating a patient suffering from asthma which comprises administering to such patient an asthma-relieving amount of a 5-sulphonyl-1,4-dihydropyridine of the formula ##STR1## in which R.sup.1 is aryl having 6 or 10 C atoms, optionally substituted by 1 to 3 identical or different substituents from the group: halogen, cyano, nitro, trifluoromethyl, trifluoromethoxy, alkoxycarbonyl (up to 4 C atoms), carboxyl, alkoxy (up to 4 C atoms) or straight-chain or branched alkyl having up to 4 C atoms,or is heteroaryl,R.sup.

Abstract: 1,4-Dihydropyridines of the formula ##STR1## in which n is 0,1 or 2, andR.sup.1 to R.sup.7 can have a wide variety of meanings, which possess inotropic action, and many of which are new, are useful in increasing the influx of Ca.sup.++ into cells, particularly in combatting coronary and vascular diseases, hypertension swelling in the mucous membranes and diseases involving increased blood sugar or an incorrect salt and fluid balance.

Abstract: The invention relates to optically active 1,4-dihydropyridine compounds of Formulas Ia and Ib as defined hereinabove which are effective for influencing circulation. Also included in the invention are compositions containing said optically active compounds and methods for the use of said compounds and compositions.

Abstract: The invention relates to substituted 2-amino-3,4-dihydropyridine derivative compounds useful, for example as lipid absorption inhibitors.Also included in the invention are methods for the manufacture of said active compounds, compositions containing them and methods for the use of said compounds and compositions.