Abstract: The present invention provides relates to an edible composition for anti-diabetic benefit. Diabetes is one of the major and commonly occurring health problems in today's world. Pharmaceuticals companies are very active in this field to develop new medicines for preventing and controlling diabetes. There are several medicines available in the market for the treatment of type 2 diabetes. There are prior arts which describes composition and/or therapies for the prevention of glucose intolerance and/or diabetes. We have found that, though prior art discloses compositions and therapies for treating diabetes, there is not disclose any food composition which is effectively controls GLP-1 activity thereby control diabetes.

Abstract: The use of a compound for the reduction or elimination of bitterness caused by flavan-3-ols is provided. Compositions having greater than 0.01 wt % flavan-3-ols and that comprise an effective amount of the compound are also provided.

Abstract: The invention relates to a nucleic acid molecule being represented by a nucleic acid sequence comprising at least three nucleic acid subsequences, each nucleic acid subsequence coding for one of the ?, ?, and ? subunits of the epithelial sodium channel, and each nucleic acid subsequence being arranged in a head to tail configuration with respect to another. The invention further relates to a cell comprising the nucleic acid sequence of the invention, which is able to express the subunits and to its use in a method for screening a potential modulator compound of the subunits of the epithelial sodium channel.

Abstract: The invention relates to Agrobacterium mediated transformation of moulds comprising species of the fungal sub-divisions Ascomycotina, Basidiomycotina, Deuteromycotina, Mastigomycotina, and Zygomycotina. Examples demonstrate the transformation of Aspergillus awamori (both protoplasts and conidia), Aspergillus nidulans, Aspergillus niger, Colletotrichum gloeosporioides, Fusarium solani pisi, Neurospora crassa, Trichoderma reesei, Pleurotus ostreatus and Agaricus bisporus (all conidia), and Fusarium graminearum (both conidia and rehydrated freeze dried ATCC material). Especially for Aspergillus awamori the transformation frequency is much higher than with conventional mould transformation techniques. It has further been found that not only one expressable gene can be introduced into these moulds, but even multiple copies of such gene, which, moreover, can be targeted e.g. in the chromosomal pyrG locus, as exemplified for A. awamori.

Abstract: Methods are described for the isolation and characterization of DNA sequences from Aspergillus niger var. awamori which are involved in the expression and secretion of endoxylanase II (exlA) by said Aspergillus mould. A process using these expression and/or secretion regulating regions to direct the production and optionally the secretion of proteins other than endoxylanase II by transformed moulds is provided.