Patents by Inventor Robin Bachelder

Robin Bachelder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Humanized Monoclonal Antibody Targeting Pro-N-Cadherin
    Publication number: 20220227881
    Abstract: Humanized antibody to a pathologically mislocated form of N-cadherin detects and eliminates cells that express the protein extracellularly. These cells are found in fibrotic conditions within heart, lung, and liver, as well as kidney, skin, and other organs effected by fibrosis. The antibody does not affect cells with normal, subcellular location of the protein.
    Type: Application
    Filed: January 24, 2022
    Publication date: July 21, 2022
    Applicant: Duke University
    Inventors: Paul Ferrell, Salvatore Pizzo, Robin Bachelder
  • Anti-pro-N-cadherin antibodies and methods of treating pathological fibrotic conditions and tumor cells
    Patent number: 11230606
    Abstract: Humanized antibody to a pathologically mislocated form of N-cadherin detects and eliminates cells that express the protein extracellularly. These cells are found in fibrotic conditions within heart, lung, and liver, as well as kidney, skin, and other organs effected by fibrosis. The antibody does not affect cells with normal, subcellular location of the protein.
    Type: Grant
    Filed: March 9, 2020
    Date of Patent: January 25, 2022
    Assignee: Duke University
    Inventors: Paul Ferrell, Salvatore Pizzo, Robin Bachelder
  • Compositions and methods for detecting and treating pathological fibroblast cells
    Patent number: 11022608
    Abstract: Compositions, kits and methods for assessing the presence of pathological fibroblasts within a biological sample are provided. In addition, compositions, kits and methods for detecting fibrosis are provided. Also provided are methods for treating fibrosis and conditions characterized with pathological fibroblasts.
    Type: Grant
    Filed: September 27, 2019
    Date of Patent: June 1, 2021
    Assignee: Duke University
    Inventors: Paul Ferrell, Salvatore Pizzo, Robin Bachelder
  • Humanized Monoclonal Antibody Targeting Pro-N-Cadherin
    Publication number: 20200369779
    Abstract: Humanized antibody to a pathologically mislocated form of N-cadherin detects and eliminates cells that express the protein extracellularly. These cells are found in fibrotic conditions within heart, lung, and liver, as well as kidney, skin, and other organs effected by fibrosis. The antibody does not affect cells with normal, subcellular location of the protein.
    Type: Application
    Filed: March 9, 2020
    Publication date: November 26, 2020
    Applicant: Duke University
    Inventors: Paul Ferrell, Salvatore Pizzo, Robin Bachelder
  • COMPOSITIONS AND METHODS FOR DETECTING AND TREATING PATHOLOGICAL FIBROBLAST CELLS
    Publication number: 20200319166
    Abstract: Compositions, kits and methods for assessing the presence of pathological fibroblasts within a biological sample are provided. In addition, compositions, kits and methods for detecting fibrosis are provided. Also provided are methods for treating fibrosis and conditions characterized with pathological fibroblasts.
    Type: Application
    Filed: June 23, 2020
    Publication date: October 8, 2020
    Inventors: Paul Ferrell, Salvatore Pizzo, Robin Bachelder
  • COMPOSITIONS AND METHODS FOR DETECTING AND TREATING PATHOLOGICAL FIBROBLAST CELLS
    Publication number: 20200103397
    Abstract: Compositions, kits and methods for assessing the presence of pathological fibroblasts within a biological sample are provided. In addition, compositions, kits and methods for detecting fibrosis are provided. Also provided are methods for treating fibrosis and conditions characterized with pathological fibroblasts.
    Type: Application
    Filed: September 27, 2019
    Publication date: April 2, 2020
    Inventors: Paul Ferrell, Salvatore Pizzo, Robin Bachelder