Abstract: A vascular prosthesis for implantation at an aortic arch of a human patient includes major tubular component defining a longitudinal axis and an island graft that has a length parallel to the longitudinal axis that is greater than a width transverse to the longitudinal axis. The vascular prosthesis delivery system includes a vascular prosthesis of the invention. The vascular prosthesis can also be a hybrid vascular prosthesis, including a proximal surgical segment that can be corrugated, an endovascular stent graft segment extending distally from the surgical segment, and a collar interposed between the surgical segment and the endovascular stent graft segment. The island graft can be pleated or corrugated and can be radially raised from a surface of the major tubular component.