Patents by Inventor Robin D. Clark

Robin D. Clark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4353900
    Abstract: Compounds useful in the prevention and/or treatment of hypertension, congestive heart failure, arrhythmia, migraine, vasospastic disorders, and asthma are represented by the formula ##STR1## wherein: R.sup.1 is ##STR2## wherein X is hydrogen, lower alkyl, lower alkoxy, halo, carboxamido or hydroxy; m is 1, 2 or 3; and n is 1, 2 or 3;R.sup.2, R.sup.3 and R.sup.4 are independently hydrogen or lower alkyl; andthe pharmaceutically acceptable acid addition salts thereof.
    Type: Grant
    Filed: October 19, 1981
    Date of Patent: October 12, 1982
    Assignee: Syntex (U.S.A.) Inc.
    Inventor: Robin D. Clark
  • Patent number: 4353901
    Abstract: Compounds useful in the prevention and/or treatment of hypertension, congestive heart failure, arrhythmia, migraine, vasospastic disorders, and asthma are represented by the formula: ##STR1## wherein:R.sup.1 is ##STR2##R.sup.2, R.sup.3, and R.sup.4 are independently hydrogen or lower alkyl of one to four carbon atoms;X is hydrogen, lower alkyl of one to four carbon atoms, lower alkoxy of one to four carbon atoms or halo;m is 1 or 2; andn is 1, 2 or 3; andthe pharmaceutically acceptable acid addition salts thereof.
    Type: Grant
    Filed: October 19, 1981
    Date of Patent: October 12, 1982
    Assignee: Syntex (U.S.A.) Inc.
    Inventor: Robin D. Clark
  • Patent number: 4349549
    Abstract: Novel compounds of the formula: ##STR1## and the pharmaceutically acceptable acid addition salts thereof, wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are each independently hydrogen, hydroxy, lower alkyl, lower alkoxy or halo;R is hydrogen or lower alkyl; andA is selected from the group consisting of:2-(benzodioxan-2-yl)-2-hydroxyethyl;.omega.-(benzodioxan-2-yl)-alkyl (1-4);3-(aryloxy)-2-hydroxypropyl, wherein aryloxy is phenyloxy optionally substituted by 1-3 moieties selected from the group consisting of lower alkyl, lower alkoxy, halo, alkylsulfamido, lower alkoxycarbonyl, cyano and trifluoromethyl;.omega.-arylalkyl (1-4), wherein aryl is phenyl optionally substituted by 1-3 moieties selected from the group consisting of lower alkyl, lower alkoxy, halo, alkylsulfamido, lower alkoxycarbonyl, cyano and trifluoromethyl;.omega.-aryl-.omega.-oxoalkyl (1-4), wherein aryl is as herein defined;.omega.-aryl-.omega.-hydroxyalkyl (1-4), wherein aryl is as herein defined; and.omega.
    Type: Grant
    Filed: May 18, 1981
    Date of Patent: September 14, 1982
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Adolph P. Roszkowski, Robin D. Clark, Arthur F. Kluge
  • Patent number: 4332804
    Abstract: Compounds useful in the prevention and/or treatment of hypertension, congestive heart failure, arrhythmia, migraine, vasospastic disorders, and asthma are represented by the formula ##STR1## wherein: R, R.sup.1, R.sup.2, R.sup.3, and R.sup.4 are independently hydrogen or lower alkyl of one to four carbon atoms; andR.sup.5 and R.sup.6 are independently hydrogen, lower alkyl of one to four carbon atoms or lower alkoxy of one to four carbon atoms; andthe pharmaceutically acceptable acid addition salts thereof.
    Type: Grant
    Filed: March 23, 1981
    Date of Patent: June 1, 1982
    Assignee: Syntex (U.S.A.) Inc.
    Inventor: Robin D. Clark