Abstract: A renal therapy system is disclosed. In an example, the renal therapy system includes a home renal therapy machine that stores, to a log file, dates of when renal therapies were performed and a type of each renal therapy that was performed. The system also includes a server that receives the log file from the home renal therapy machine. The server compares the dates and types of performed renal therapies stored in the log file to a device program that specifies dates for performing renal therapies and the types of renal therapies to be performed. The server displays a flag in a user interface of a clinician computer when there is a deviation from the comparison.

Abstract: A renal therapy system is disclosed. In an example, the renal therapy system includes a user interface device, such as a tablet computer. The renal therapy system also includes a renal therapy machine configured to perform a renal therapy. The renal therapy machine includes a data transfer interface configured to communicatively couple to the user interface device, a dialysis fluid pump, and a processor that operates a connectivity agent having an activated mode and a deactivated mode. When in the activated mode, the connectivity agent enables the processor to send data related to a performance of the renal therapy to a system hub. In the deactivated mode, the processor is prevented from sending the data to or receiving any data from the system hub. The user interface device is configured to receive data from and send data to the processor regardless of a status of the connectivity agent.

Abstract: A renal therapy system is disclosed. In an example, the renal therapy system includes a user interface device, such as a tablet computer. The renal therapy system also includes a renal therapy machine configured to perform a renal therapy. The renal therapy machine includes a data transfer interface configured to communicatively couple to the user interface device, a dialysis fluid pump, and a processor that operates a connectivity agent having an activated mode and a deactivated mode. When in the activated mode, the connectivity agent enables the processor to send data related to a performance of the renal therapy to a system hub. In the deactivated mode, the processor is prevented from sending the data to or receiving any data from the system hub. The user interface device is configured to receive data from and send data to the processor regardless of a status of the connectivity agent.

Abstract: A renal therapy system is disclosed. In an example, a renal therapy system includes a dialysis fluid pump, a control processor for controlling a treatment performed by the dialysis fluid pump, and a user interface device in operable communication with the control processor.

Abstract: A computer readable medium stores instructions configured to cause a home therapy machine to allow an at home patient selection of a device program from a plurality of device programs stored on the home therapy machine and perform an at home treatment using fluid flow equipment provided by the home therapy machine according to the selected device program. The instructions are further configured to receive data generated during the at home treatment and generate at least one log file based upon the received data.

Abstract: A method for performing renal therapy at a home or dwelling of a patient using a renal therapy machine includes electronically retrieving a doctor's prescription for renal therapy and based on the doctor's prescription, enabling electronic selection of supplies, including a dialyzer, at a first location other than the patient's home or dwelling by a person other than the patient. The method further includes electronically initiating a sending of the supplies and the renal therapy machine to the patient's home or dwelling.

Abstract: A home medical device system includes a plurality of home therapy machines that perform a home therapy on a patient; a connectivity server; a system hub coupled to the home therapy machines through the connectivity server; a web portal configured to access the system hub; a plurality of clinics connected to the system hub via the web portal; and a website accessible via the web portal, the website including a patient portion available to patients using the plurality of home therapy machines, the website further including a clinician portion that enables the clinics to manage the home therapy machines.

Abstract: A home therapy entry, modification and reporting system includes a website configured to display therapy entry, modification and reporting information and a system hub configured to manage a flow of the information between the website and a plurality of home therapy machines. The website specifically includes a therapy prescription screen configured to specify supplies needed at the patient's home or dwelling for operation with one of the home therapy machines, a device program screen configured to set parameters by which at least one of the home therapy machines operates to perform the home therapy on the patient, and a clinician dashboard screen including a list of patients and a notification associated with at least one of the listed patients, the notification indicating whether a predefined treatment condition or alert occurred during the home therapy.

Abstract: A home therapy machine is configured to perform a home therapy on a patient at a home or dwelling of the patient. The home therapy machine includes at least one processor operating a connectivity agent having an activated mode and a deactivated mode. When the connectivity agent is in the activated mode, the at least one processor is able to send data to and receive data from a system hub. When the connectivity agent is in the deactivated mode, the at least one processor is not able to send data to or receive data from the system hub. The home therapy machine further includes a user interface configured to receive a patient selection of a device program received from the system hub and at least one pump under control of the at least one processor for performing the home therapy according to the selected device program.

Abstract: A home therapy machine is configured to perform a home therapy on a patient at a home or dwelling of the patient. The home therapy machine includes at least one processor operating a connectivity agent having an activated mode and a deactivated mode. When the connectivity agent is in the activated mode, the at least one processor is able to send data to and receive data from a system hub. When the connectivity agent is in the deactivated mode, the at least one processor is not able to send data to or receive data from the system hub. The home therapy machine further includes a user interface configured to receive a patient selection of a device program received from the system hub and at least one pump under control of the at least one processor for performing the home therapy according to the selected device program.

Abstract: A computer readable medium stores instructions configured to cause a home therapy machine to allow an at home patient selection of a device program from a plurality of device programs stored on the home therapy machine and perform an at home treatment using fluid flow equipment provided by the home therapy machine according to the selected device program. The instructions are further configured to receive data generated during the at home treatment and generate at least one log file based upon the received data.

Abstract: A method for performing renal therapy at a home or dwelling of a patient using a renal therapy machine includes electronically retrieving a doctor's prescription for renal therapy and based on the doctor's prescription, enabling electronic selection of supplies, including a dialyzer, at a first location other than the patient's home or dwelling by a person other than the patient. The method further includes electronically initiating a sending of the supplies and the renal therapy machine to the patient's home or dwelling.

Abstract: A home therapy entry, modification and reporting system includes a website configured to display therapy entry, modification and reporting information and a system hub configured to manage a flow of the information between the website and a plurality of home therapy machines. The website specifically includes a therapy prescription screen configured to specify supplies needed at the patient's home or dwelling for operation with one of the home therapy machines, a device program screen configured to set parameters by which at least one of the home therapy machines operates to perform the home therapy on the patient, and a clinician dashboard screen including a list of patients and a notification associated with at least one of the listed patients, the notification indicating whether a predefined treatment condition or alert occurred during the home therapy.

Abstract: A home medical device system includes a plurality of home therapy machines that perform a home therapy on a patient; a connectivity server; a system hub coupled to the home therapy machines through the connectivity server; a web portal configured to access the system hub; a plurality of clinics connected to the system hub via the web portal; and a website accessible via the web portal, the website including a patient portion available to patients using the plurality of home therapy machines, the website further including a clinician portion that enables the clinics to manage the home therapy machines.

Abstract: This invention relates to a combinatorial process for synthesizing a library of azetidinone peptide-like compounds. The compounds are synthesized as mixtures from a common azetidinone intermediate. The compounds are biologically active as inhibitors of the Vasopressin (V1a) receptor.