Abstract: The present invention relates to a method and composition for treating melanoma. More particularly, inventors have shown that high expression of USP14 correlates with melanoma progression and with a poorer survival rate in metastatic melanoma patients. Then, they have shown that an inhibition of ubiquitin-specific peptidase 14 (USP14) by siRNAs and pharmacological inhibitors (b-AP15, WP1130 and HBX41108), the cell proliferation of melanoma cell drastically decreased. They have also shown that melanoma treatment with pharmacological inhibitors can overcome resistance to drugs targeting oncogenic BRAF. Accordingly, the invention relates to a method for predicting the survival time of a subject suffering from melanoma by quantifying the expression level of USP14 in a biological sample and to a method of treating melanoma and resistant melanoma by using the inhibitors of USP14.

Abstract: The present invention relates to a data routing and processing device comprising a data bus, a router for managing communications on the data bus, data processing unit and a local memory for temporarily storing data. A transmitting processing unit transmits to the router an identifier. The router comprises a communication table which enables it to determine the receiving processing unit based on the identifier. The router ensures a communication between the transmitting processing unit and the receiving processing unit depending on a value of an availability register. If the receiving processing unit is available, the data transfer is direct; if not, the data transfer takes place via the local memory.

Abstract: The invention relates to a method of video processing applied to N encoded video input signals, for decoding and reducing by a factor N the format of said encoded video input signals, and for generating a set of decoded video signals in the pixel domain, each encoded video input signal comprising DCT blocs. The method according to the invention is characterized in that it comprises a first and second inverse DCT step, each inverse DCT step being applied simultaneously on a plurality of DCT blocs of reduced size extracted from said N encoded video input signals. Thus are generated N output blocs of reduced size defining one of said decoded video signal of reduced format by a factor N. This invention can advantageously be used for the composition of mosaic video signals from a set of encoded signals.

Abstract: In a system integrating modules (PROC) designed for a time-slotted resource-accessing scheme and modules (PROC′) designed for accessing a common resource based on request-arbitration, a request-arbitration scheme is used for managing access to a common resource. The module(s) (PROC) designed for a time-slotted resource-accessing scheme are associated with an anticipatory request generator (ARG) adapted to generate, and forward to the arbiter (P_ARB), anticipated requests produced ahead of the time instants when the associated modules are designed to make access requests. A data buffer (DATA BUF) is also associated with each of the modules designed for a time-slotted resource-accessing scheme, so as to hold data obtained as a result of an anticipated request until the time instant when the module generates the request associated with this data.

Abstract: The present invention relates to a data routing and processing device comprising a data bus, a router (15) for managing communications on the data bus, data processing units (11, 12) and a local memory (16) for temporarily storing data. A transmitting processing unit (11) transmits to the router an identifier (ID1). The router comprises a communication table (151) which enables it to determine the receiving processing unit (12) based on the identifier. The router ensures a communication between the transmitting processing unit (11) and the receiving processing unit (12) depending on a value of an availability register (tag). If the receiving processing unit is available, the data transfer is direct; if not, the data transfer takes place via the local memory (16).

Abstract: The invention relates to a method of video processing applied to N encoded video input signals, for decoding and reducing by a factor N the format of said encoded video input signals, and for generating a set of decoded video signals in the pixel domain, each encoded video input signal comprising DCT blocs. The method according to the invention is characterized in that it comprises a first and second inverse DCT step, each inverse DCT step being applied simultaneously on a plurality of DCT blocs of reduced size extracted from said N encoded video input signals. Thus are generated N output blocs of reduced size defining one of said decoded video signal of reduced format by a factor N.

Abstract: In a system integrating modules (PROC) designed for a time-slotted resource-accessing scheme and modules (PROC′) designed for accessing a common resource based on request-arbitration, a request-arbitration scheme is used for managing access to a common resource. The module(s) (PROC) designed for a time-slotted resource-accessing scheme are associated with an anticipatory request generator (ARG) adapted to generate, and forward to the arbiter (P_ARB), anticipated requests produced ahead of the time instants when the associated modules are designed to make access requests. A data buffer (DATA BUF) is also associated with each of the modules designed for a time-slotted resource-accessing scheme, so as to hold data obtained as a result of an anticipated request until the time instant when the module generates the request associated with this data.