Abstract: Provided are compounds of Formula (I) or pharmaceutically acceptable salts thereof, wherein the variables in Formula (I) are as defined herein; and methods for their use and production.

Abstract: Provided are compounds of Formula (I): or pharmaceutically acceptable salts thereof, wherein the variables in Formula (I) are as defined herein; and methods for their use and production.

Abstract: A system can include a nonlinear circuit and a voltage decoder. The nonlinear circuit can perform an operation on an input voltage. The operation can be changed. A voltage decoder can be communicatively coupled to the nonlinear circuit for receiving an output voltage from the nonlinear circuit that results from the operation performed on the input voltage. The voltage decoder can compare the output voltage to a threshold voltage and determine a result of the operation.

Abstract: A system can include a nonlinear circuit and a voltage decoder. The nonlinear circuit can perform an operation on an input voltage. The operation can be changed. A voltage decoder can be communicatively coupled to the nonlinear circuit for receiving an output voltage from the nonlinear circuit that results from the operation performed on the input voltage. The voltage decoder can compare the output voltage to a threshold voltage and determine a result of the operation.

Abstract: The present disclosure discloses an anti-inflammatory composition comprising turmeric alcohol extract, beta caryophyllene, 3-o-acetyl-11-keto-beta-boswellic acid, extract obtained from Kaempferia galanga and turmeric water extract. The present disclosure also describes a process of preparing the composition containing these extracts, which mainly involves extracting curcumin alcohol extract from turmeric, extracting gum resin from Boswellia serrata, AKBA is isolated from the extracted gum resin and complexed with phospholipid, beta-caryophyllene is isolated from Piper nigrum by steam distillation and subjected to fractionation for purification, flavonoids rich aqueous extract is extracted from Kaempferia galanga and turmeric water extract powder is obtained from Curcuma longa. The extracts are combined together to form a complete natural matrix, homogenized and subjected to spray drying to obtain a uniform mixture in a powdered form.

Abstract: An umbrella has a handle with a top end and a bottom end, wherein a shaft extends from the top end of the handle to a canopy, and a quick-release mounting feature is disposed on the handle.

Abstract: The present invention discloses a process for preparation of white curcumin from purified curcuminoids. The curcuminoids are obtained by solvent extraction and crystallization of dried turmeric powder. The autoclave is charged with ethyl acetate and the 95% purity curcuminoids mixture is added to and stirred for uniformity at room temperature. 5% (w/w) of 10% palladium carbon is added to the reaction mixture and allowed for hydrogenation in the presence of hydrogen gas at 2 lbps pressure and stirred continuously for 15 hours. Once the reaction is completed, the reaction mixture is filtered and washed with ethyl acetate. The ethyl acetate is distilled off and crude mass is stirred with water to obtain a solid precipitate. Finally, the solid obtained is filtered and dried to pale brown crystals of white curcumin. White curcumin is encapsulated with beta-cyclodextrin, which exhibited increased bioavailability. White curcumin also exhibited anti-oxidant and chemopreventive activities.

Abstract: The present disclosure discloses an anti-inflammatory composition comprising turmeric alcohol extract, beta caryophyllene, 3-o-acetyl-11-keto-beta-boswellic acid, extract obtained from Kaempferia galangal and turmeric water extract. The present disclosure also describes a process of preparing the composition containing these extracts, which mainly involves extracting curcumin alcohol extract from turmeric, extracting gum resin from Boswellia serrata, AKBA is isolated from the extracted gum resin and complexed with phospholipid, beta-caryophyllene is isolated from Piper nigrum by steam distillation and subjected to fractionation for purification, flavonoids rich aqueous extract is extracted from Kaempferia galangal and turmeric water extract powder is obtained from Curcuma longa. The extracts are combined together to form a complete natural matrix, homogenized and subjected to spray drying to obtain a uniform mixture in a powdered form.

Abstract: The present invention discloses a process for preparation of white curcumin from purified curcuminoids. The curcuminoids are obtained by solvent extraction and crystallization of dried turmeric powder. The autoclave is charged with ethyl acetate and the 95% purity curcuminoids mixture is added to and stirred for uniformity at room temperature. 5% (w/w) of 10% palladium carbon is added to the reaction mixture and allowed for hydrogenation in the presence of hydrogen gas at 2 lbps pressure and stirred continuously for 15 hours. Once the reaction is completed, the reaction mixture is filtered and washed with ethyl acetate. The ethyl acetate is distilled off and crude mass is stirred with water to obtain a solid precipitate. Finally, the solid obtained is filtered and dried to pale brown crystals of white curcumin. White curcumin is encapsulated with beta-cyclodextrin, which exhibited increased bioavailability. White curcumin also exhibited anti-oxidant and chemopreventive activities.

Abstract: The present invention relates to a digital display plotter for plotting images on a digital display device 18. A cursive imagery generator 12 generates imagery inputs at a plurality of respective update phases during a refresh period of the display device. A control 20 for the display device activates selected pixels of the digital display device in response to respective said imagery inputs, activation being controlled subsequent to each update phase during a refresh period. An input store 14, 16 associates each cursively generated imagery input with an update phase that the imagery input was generated during a refresh period. The control 20 is responsive to the input store and configured to deactivate the selected pixels activated in response to each imagery input dependent on the associated update phase of each imagery input.

Abstract: The present invention relates to a digital display plotter for plotting images on a digital display device 18. A cursive imagery generator 12 generates imagery inputs at a plurality of respective update phases during a refresh period of the display device. A control 20 for the display device activates selected pixels of the digital display device in response to respective said imagery inputs, activation being controlled subsequent to each update phase during a refresh period. An input store 14, 16 associates each cursively generated imagery input with an update phase that the imagery input was generated during a refresh period. The control 20 is responsive to the input store and configured to deactivate the selected pixels activated in response to each imagery input dependent on the associated update phase of each imagery input.

Abstract: A method for recalling a message and a device thereof are provided, thereby efficiently satisfying a message recall demand, and improving a service quality of a message service. The method includes: sending a message recall request to a message receiving device, in which the message recall request carries a message identifier of the message to be recalled and a message authentication header field, and the message authentication header field includes an encryption algorithm and a random number generated by encrypting a random number for authenticating the message through the encryption algorithm, so that the message receiving device determines the message to be recalled according to the message ID and the message authentication header field, and disposes the message to be recalled according to a local policy and a delivery status of the message to be recalled; and receiving a message recall disposition result returned by the message receiving device.

Abstract: A display apparatus (20) includes an electromagnetic radiation source (22) and digital micro-mirror device (21) having a plurality of micro-mirror elements on a surface thereof. The electromagnetic radiation source (22) is arranged to illuminate the digital micro-mirror device (21) and at least one micro-mirror element of the digital micro-mirror device (21) either reflects electromagnetic radiation along a primary path (23) to an exit lens (23) to form a desired image to be viewed by an operator or along a secondary path (25) to an electromagnetic radiation dump (26). The digital micro-mirror device (21) is also operable to generate a test image at the electromagnetic radiation dump (26) at a predetermined time.

Abstract: A display apparatus (20) includes an electromagnetic radiation source (22) and digital micro-mirror device (21) having a plurality of micro-mirror elements on a surface thereof. The electromagnetic radiation source (22) is arranged to illuminate the digital micro-mirror device (21) and at least one micro-mirror element of the digital micro-mirror device (21) either reflects electromagnetic radiation along a primary path (23) to an exit lens (23) to form a desired image to be viewed by an operator or along a secondary path (25) to an electromagnetic radiation dump (26). The digital micro-mirror device (21) is also operable to generate a test image at the electromagnetic radiation dump (26) at a predetermined time.

Abstract: Compounds of formula (I) wherein Rx is H; Ry is H or C1-C4 alkyl; each Rz is independently H or C1-C4 alkyl; X represents O; Y represents OH or OR; R is C1-C4 alkyl; and Ar1 and Ar2 are optionally substituted phenyl or 5- or 6-membered heteroaryl rings are selective inhibitors of the reuptake of norepinephrine.

Abstract: A method of, and apparatus for, processing interference in a cellular communications system. The method includes the steps of determining a quality value per burst; identifying those bursts for which the quality value is below a predetermined threshold; determining a pattern of the identified bursts in terms of transmission frequency and time; calculating respective predicted patterns based on respective hopping determination parameters of other cells and of the given cell; comparing the determined pattern of the identified bursts with the predicted patterns; and responsive thereto predicting the hopping determination parameters of whichever interfering cell produced the determined pattern of the identified bursts by interfering with the given cell. Further possibilities include comparing the given cell with the interfering cell and identifying predicted interfering timeslots. Further interference can be reduced by not transmitting bursts during some or all of the predicted interfering timeslots.

Abstract: A device for supporting a wire on a post, having a body with a base portion and two arm portions which extend away from the base portion generally in the same direction. A wire receiving opening is formed between the two arm portions. To use the device, it is affixed to a post at one arm portion and with the opening upwardly open. The wire to be supported is then inserted into the opening, between the arm portions, after which the arm portion which is not affixed to the post is deformed inwardly towards the post to substantially close the opening around the wire so that the wire is captured by the device.

Abstract: Disclosed is a method and apparatus for protecting electronic contacts on printer ink cartridges during insertion to and removal from a printer. The method includes inserting a protective strip (10) into the cradle (18) of the printer such that at least a portion of the strip resides between the electronic contacts during removal or insertion of the cartridge (15).

Abstract: Disclosed is an apparatus and associated method for refilling a used ink cartridge of an ink jet printer with ink. Such cartridges have an aperture (30) through which ink can be inserted. Surrounding the aperture is a funnel (21) having a resiliently deformable washer (22) therein. The washer (22) has a tapered aperture (23) defining therebeneath a void space (25) which can have air entrapped therein. A refilling apparatus to be associated with an ink refill bottle includes a plug element (10) including a tip portion (13) to be received within the aperture (30). A widened portion (18) bears upon the washer (23) so as to expel any air entrapped therein to prevent such air passing into the ink cartridge when refilling with ink.