Abstract: Described herein are methods and computer systems for classification of CD8 T-cell topology using a patient response-based linear cutoff model. A plurality of histology images of tissue samples in a plurality of patients are received by a computer system. An image analysis of the plurality of histology images is performed to obtain a CD8+ T-cell abundance in the tumor parenchyma and stroma in each of the plurality of histology images. Real inflammation scores and tumor infiltration scores are determined based on a polar coordinate transformation of the CD8+ T-cell abundance in the tumor parenchyma and stroma. Based on the real inflammation scores and tumor infiltration scores, a feature space is generated, and linear boundaries or linear cutoffs between a plurality of classifications in the feature space are identified based on the real inflammation scores, the tumor infiltration scores, and patient response data.

Abstract: A power outlet device for regulating the operation of an appliance, such as a window mounted air conditioner is provided. The device includes a power inlet and a power outlet coupled to a switch. A controller having a communications device controls the state of the switch. The controller is connected to a temperature sensor that measures the ambient temperature of the room. A user interface allows the user to define a maximum temperature for the room. In response to the receipt of a signal via the communications device, the controller regulates the flow of electrical power to the appliance based on the defined maximum temperature. A timer is also provided that minimizes short time period cycling of the appliance.

Abstract: A process for the preparation of a lavatory cleansing tablet for immersion in the cistern of a lavatory comprises forming a free-flowing particulate mixture consisting essentially of:(a) from 5 to 90% by weight of a surface active component comprising one or more organic surface active agents, especially anionic or nonionic surface active agents;(b) from 0.