Patents by Inventor Robin H. Lachmann

Robin H. Lachmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Viral vectors
    Publication number: 20010012516
    Abstract: Constructs for delivery of sequences of interest to cells include a herpes virus latency active promoter (LAP) of the latency associated transcript (LAT) region. An internal ribosome entry site (IRES) is located downstream of the LAP, with a nucleotide sequence of interest downstream of the IRES. Stable, long-term expression, including export of mRNA to the cytoplasm and translation of the encoded polypeptide, is found in neuronal and non-neuronal cells.
    Type: Application
    Filed: January 19, 2001
    Publication date: August 9, 2001
    Inventors: Stacey Efstathiou, Robin H. Lachmann
  • Replication defective herpes simplex virus comprising heterologous inserts
    Patent number: 6193980
    Abstract: Constructs for the delivery of sequences of interest to cells include a herpes virus latency active promoter (LAP) of the latency associated transcript (LAT) region. An internal ribosome entry site (IRES) is located downstream of the LAP, with a nucleotide sequence of interest downstream of the IRES. Stable, long-term expression including export of mRNA to the cytoplasm and translation of the encoded polypeptide, is found in neuronal and non-neuronal cells.
    Type: Grant
    Filed: September 17, 1997
    Date of Patent: February 27, 2001
    Assignee: Cambridge University Technical Services, Limited
    Inventors: Stacey Efstathiou, Robin H. Lachmann