Patents by Inventor Robin L. Thurmond

Robin L. Thurmond has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diamino-Pyridine, Pyrimidine, and Pyridazine Modulators of the Histamine H4 Receptor
    Publication number: 20170298022
    Abstract: Diamino-pyridine, pyrimidine and pyridazine compounds which may be used as H4 receptor modulators, and in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as allergy, asthma, autoimmune diseases, and pruritis.
    Type: Application
    Filed: June 28, 2017
    Publication date: October 19, 2017
    Inventors: Hui Cai, Frank Chavez, Paul J. Dunford, Andrew J. Greenspan, Steven P. Meduna, Jorge A. Quiroz, Brad M. Savall, Kevin L. Tays, Robin L. Thurmond, Jianmei Wei, Ronald L. Wolin, Xiaohu Zhang
  • Diamino-pyridine, pyrimidine, and pyridazine modulators of the histamine Hreceptor
    Patent number: 9732087
    Abstract: Diamino-pyridine, pyrimidine and pyridazine compounds which may be used as H4 receptor modulators, and in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as allergy, asthma, autoimmune diseases, and pruritis.
    Type: Grant
    Filed: August 14, 2014
    Date of Patent: August 15, 2017
    Assignee: JANSSEN PHARMACEUTICA N.V.
    Inventors: Hui Cai, Frank Chavez, Paul J. Dunford, Andrew J. Greenspan, Steven P. Meduna, Jorge A. Quiroz, Brad M. Savall, Kevin L. Tays, Robin L. Thurmond, Jianmei Wei, Ronald L. Wolin, Xiaohu Zhang
  • Diamino-Pyridine, Pyrimidine, and Pyrazine Modulators of the Histamine H4 Receptor
    Publication number: 20140357614
    Abstract: Diamino-pyridine, pyrimidine and pyridazine compounds which may be used as H4 receptor modulators, and in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as allergy, asthma, autoimmune diseases, and pruritis.
    Type: Application
    Filed: August 14, 2014
    Publication date: December 4, 2014
    Inventors: Hui Cai, Frank Chavez, Paul J. Dunford, Andrew J. Greenspan, Steven P. Meduna, Jorge A. Quiroz, Brad M. Savall, Kevin L. Tays, Robin L. Thurmond, Jianmei Wei, Ronald L. Wolin, Xioahu Zhang
  • Diamino-pyridine, pyrimidine, and pyrazine modulators of the histamine H4 receptor
    Patent number: 8841287
    Abstract: Diamino-pyridine, pyrimidine and pyridazine compounds which may be used as H4 receptor modulators, and in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as allergy, asthma, autoimmune diseases, and pruritis.
    Type: Grant
    Filed: June 11, 2009
    Date of Patent: September 23, 2014
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Hui Cai, Frank Chavez, Paul J. Dunford, Andrew J. Greenspan, Steven P. Meduna, Jorge A. Quiroz, Brad M. Savall, Kevin L. Tays, Robin L. Thurmond, Jianmei Wei, Ronald L. Wolin, Xiaohu Zhang
  • Diamino-pyridine, pyrimidine, and pyrazine modulators of the histamine H4 receptor
    Publication number: 20110092474
    Abstract: Diamino-pyridine, pyrimidine and pyridazine compounds which may be used as H4 receptor modulators, and in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as allergy, asthma, autoimmune diseases, and pruritis.
    Type: Application
    Filed: June 11, 2009
    Publication date: April 21, 2011
    Inventors: Hui Cai, Frank Chavez, Paul J. Dunford, Andrew J. Greenspan, Steven P. Meduna, Jorge A. Quiroz, Brad M. Savall, Kevin L. Tays, Robin L. Thurmond, Jianmei Wei, Ronald L. Wolin, Xiaohu Zhang
  • Use of Histamine H4 antagonist for the treatment of post-operative adhesions
    Publication number: 20110076324
    Abstract: The present invention includes methods for the inhibition of post-operative adhesion formation between tissue surfaces in a body cavity having been subjected to a surgical procedure, which methods involve administering a histamine H4 receptor antagonist, systemically, directly to tissue surfaces in the body cavity, or both, and to delivery vehicles and compositions suitable for use for local, non-systemic administration of a drug to the body and directly to tissue within a body cavity having been subjected to a surgical procedure.
    Type: Application
    Filed: June 11, 2009
    Publication date: March 31, 2011
    Applicant: JANSSEN PHARMACEUTICA NV
    Inventors: Robin L. Thurmond, Scott A. Wadsworth
  • Combination Histamine H1R and H4R Antagonist Therapy for Treating Pruritus
    Publication number: 20090069343
    Abstract: Patients suffering from pruritus or itch may be effectively treated by administering a centrally acting histamine H1 receptor antagonist (e.g., diphenhydramine, triprolidine, hydroxyzine, pyrilamine, promethazine, or chlorpheniramine) and a histamine H4 receptor antagonist (e.g., 5-chloro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone).
    Type: Application
    Filed: April 9, 2007
    Publication date: March 12, 2009
    Inventors: Paul J. Dunford, Lars Karlsson, Robin L. Thurmond
  • Method for treating allergies using substituted pyrazoles
    Patent number: 7332494
    Abstract: A method for treating an allergic condition, including an atopic allergic condition, using substituted pyrazoles.
    Type: Grant
    Filed: February 13, 2002
    Date of Patent: February 19, 2008
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Yin Gu, Darin J. Gustin, Lars Karlsson, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Siquan Sun, Kevin L. Tays, Robin L. Thurmond, Jianmei Wei
  • Heterocyclic compounds
    Patent number: 6803362
    Abstract: Heterocyclic compounds and methods of making them and using them.
    Type: Grant
    Filed: March 8, 2002
    Date of Patent: October 12, 2004
    Assignee: Ortho-McNeil Pharmaceutical inc.
    Inventors: Nicholas I. Carruthers, Wenying Chai, Curt A. Dvorak, James P. Edwards, Cheryl A. Grice, Jill A. Jablonowski, Lars Karlsson, Haripada Khatuya, Jennifer D. Kreisberg, Annette K. Kwok, Timothy W. Lovenberg, Kiev S. Ly, Barbara Pio, Chandravadan R. Shah, Siguan Sun, Robin L. Thurmond, Jianmei Wei, Wei Xiao
  • Method to treat allergic rhinitis
    Publication number: 20040132715
    Abstract: A method to treat allergic rhinitis is disclosed in which patients are administered certain indolyl compounds.
    Type: Application
    Filed: September 5, 2003
    Publication date: July 8, 2004
    Inventors: Paul J. Dunford, James P. Edwards, Lars Karlsson, Wai-Ping Leung, Robin L. Thurmond, Jianmei Wei
  • Use of histamine H4 receptor modulators for the treatment of allergy and asthma
    Publication number: 20040127395
    Abstract: Methods are disclosed for identifying histamine receptor modulators that affect mast cell or basophil chemotaxis, and the use of such histamine H4 receptor modulators for the prevention, treatment, induction, or other desired modulation of asthma and/or allergic responses, or diseases and/or conditions that are modulated, affected or caused by asthma or allergic responses. Also disclosed is the use of histamine H4 receptor modulators for the prevention, treatment, induction, or other desired modulation of mast cell or basophil chemotactic responses, such as migration to a particular site, or diseases and/or conditions that are modulated, affected or caused by mast cell or basophil chemotaxis.
    Type: Application
    Filed: September 5, 2003
    Publication date: July 1, 2004
    Inventors: Pragnya J. Desai, Paul J. Dunford, Claudia L. Hofstra, Lars G. Karlsson, Wai-Ping Leung, Ping Ling, Robin L. Thurmond
  • Heterocyclic compounds
    Publication number: 20030207893
    Abstract: Heterocyclic compounds and methods of making them and using them.
    Type: Application
    Filed: March 8, 2002
    Publication date: November 6, 2003
    Inventors: Nicholas I. Carruthers, Wenying Chai, Curt A. Dvorak, James P. Edwards, Cheryl A. Grice, Jill A. Jablonowski, Lars Karlsson, Haripada Khatuya, Jennifer D. Kreisberg, Annette K. Kwok, Timothy W. Lovenberg, Kiev S. Ly, Barbara Pio, Chandravadan R. Shah, Siquan Sun, Robin L. Thurmond, Jianmei Wei, Wei Xiao
  • Method for treating allergies using substituted pyrazoles
    Patent number: 6583155
    Abstract: A method for treating an allergic condition, including an atopic allergic condition, using substituted pyrazoles.
    Type: Grant
    Filed: February 13, 2002
    Date of Patent: June 24, 2003
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Christopher R. Butler, Hui Cai, James P. Edwards, Cheryl A. Grice, Yin Gu, Darin J. Gustin, Lars Karlsson, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Clark A. Sehon, Siquan Sun, Kevin L. Tays, Robin L. Thurmond, Jianmei Wei
  • Method for treating allergies using substituted pyrazoles
    Patent number: 6579896
    Abstract: A method for the treatment of an allergic condition, including an an atopic allergic conditions, using substituted pyrazoles.
    Type: Grant
    Filed: September 5, 2001
    Date of Patent: June 17, 2003
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Hui Cai, James P. Edwards, Yin Gu, Lars Karlsson, Steven P. Meduna, Barbara A. Pio, Siquan Sun, Robin L. Thurmond, Jianmei Wei
  • Method for treating allergies using substituted pyrazoles
    Publication number: 20030069240
    Abstract: A method for treating an allergic condition, including an atopic allergic condition, using substituted pyrazoles.
    Type: Application
    Filed: February 13, 2002
    Publication date: April 10, 2003
    Inventors: J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Yin Gu, Darin J. Gustin, Lars Karlsson, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Siquan Sun, Kevin L. Tays, Robin L. Thurmond, Jianmei Wei
  • Method for treating allergies using substituted pyrazoles
    Publication number: 20020147189
    Abstract: A method for the treatment of an allergic condition, including an an atopic allergic conditions, using substituted pyrazoles.
    Type: Application
    Filed: September 5, 2001
    Publication date: October 10, 2002
    Inventors: Hui Cai, James P. Edwards, Yin Gu, Lars Karlsson, Steven P. Meduna, Barbara A. Pio, Siquan Sun, Robin L. Thurmond, Jianmei Wei
  • Method for treating allergies using substituted pyrazoles
    Publication number: 20020115656
    Abstract: A method for treating an allergic condition, including an atopic allergic condition, using substituted pyrazoles.
    Type: Application
    Filed: February 13, 2002
    Publication date: August 22, 2002
    Inventors: Christopher R. Butler, Hui Cai, James P. Edwards, Cheryl A. Grice, Yin Gu, Darin J. Gustin, Lars Karlsson, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Clark A. Sehon, Siquan Sun, Kevin L. Tays, Robin L. Thurmond, Jianmei Wei
  • Method for treating allergies using substituted pyrazoles
    Publication number: 20020055497
    Abstract: A method for treating an allergic condition, including an atopic allergic condition, using substituted pyrazoles.
    Type: Application
    Filed: September 5, 2001
    Publication date: May 9, 2002
    Inventors: Christopher R. Butler, Hui Cai, James P. Edwards, Cheryl A. Grice, Yin Gu, Darin J. Gustin, Lars Karlsson, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Clark A. Sehon, Siquan Sun, Kevin L. Tays, Robin L. Thurmond, Jianmei Wei
  • Method for treating allergies
    Patent number: 6369032
    Abstract: Use of cathepsin S inhibitors for the treatment of an allergic condition, in particular an atopic allergic condition, more specifically for the treatment of hay fever, asthma, atopic dermatitis or a food allergy.
    Type: Grant
    Filed: September 5, 2001
    Date of Patent: April 9, 2002
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Yin Gu, Lars Karlsson, Siquan Sun, Robin L. Thurmond
  • Method for treating allergies
    Publication number: 20020035108
    Abstract: Use of cathepsin S inhibitors for the treatment of an allergic condition, in particular an atopic allergic condition, more specifically for the treatment of hay fever, asthma, atopic dermatitis or a food allergy.
    Type: Application
    Filed: September 5, 2001
    Publication date: March 21, 2002
    Inventors: Yin Gu, Lars Karlsson, Siquan Sun, Robin L. Thurmond