Patents by Inventor Robin M. MEYERS

Robin M. MEYERS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods relating to the detection of recurrent and non-specific double strand breaks in the genome
    Patent number: 10640820
    Abstract: Described herein are methods and systems relating to high throughput, genome-wide translocation sequencing (HTGTS) and/or detection of double-stranded DNA break (DSB) locations. The methods described herein can comprise generating DSBs in a nucleic acid sequence and performing nested PCR with the primers described herein. Described herein is an enhanced HTGTS approach. The assays and methods described herein permit the measurement of various DNA double-strand break (DSB) activities either intrinsic to the biological system or from outside agents.
    Type: Grant
    Filed: November 20, 2015
    Date of Patent: May 5, 2020
    Assignee: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Frederick W. Alt, Richard L. Frock, Jiazhi Hu, Robin M. Meyers
  • METHODS RELATING TO THE DETECTION OF RECURRENT AND NON-SPECIFIC DOUBLE STRAND BREAKS IN THE GENOME
    Publication number: 20180346977
    Abstract: Described herein are methods and systems relating to high throughput, genome-wide translocation sequencing (HTGTS) and/or detection of double-stranded DNA break (DSB) locations. The methods described herein can comprise generating DSBs in a nucleic acid sequence and performing nested PCR with the primers described herein. Described herein is an enhanced HTGTS approach. The assays and methods described herein permit the measurement of various DNA double-strand break (DSB) activities either intrinsic to the biological system or from outside agents.
    Type: Application
    Filed: November 20, 2015
    Publication date: December 6, 2018
    Applicant: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Frederick W. ALT, Richard L. FROCK, Jiazhi HU, Robin M. MEYERS