Patents by Inventor Robin Shepherd

Robin Shepherd has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of (+)mefloquine for the treatment of malaria
    Patent number: 6664397
    Abstract: Use of (+)-(11R,2′S)-&agr;-2-piperidinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol or a pharmaceutically acceptable salt thereof substantially free of its (−)-enantiomer in the manufacture of a medicament having reduced side-effect compared to the racemic (±)-(R*,S*)-&agr;-2-piperidinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol for treating or preventing malaria in a subject. A method of treating or preventing malaria with reduced side-effects comprising administration of (+)-(11R,2′S)-&agr;-2-piperidinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol or a pharmaceutically acceptable salt thereof substantially free of its (−)-enantiomer.
    Type: Grant
    Filed: November 22, 1999
    Date of Patent: December 16, 2003
    Assignee: Vernalis Research Limited
    Inventors: Allan Fletcher, Robin Shepherd
  • (?)-mefloquine to block puringergic receptors and to treat movement or neurodegenerative disorders
    Patent number: 6197788
    Abstract: The present invention relates to the use of (±)-R*,S*)-alpha-2-piperidnyl-2,8-bis(trifluoromethyl)-4-quinolinemthanol and in particular (−)-(11S,2′R)-alpha-2-piperidnyl-2,8-bis(trifluoromethyl)-4-quinolinemthanol in the treatment of disorders in which the reduction of purinergic neurotransmission could be beneficial. The invention relates in particular to adenosine receptors, and particularly adenosine A2a receptors and to the treatment of movement disorders such as Parkinson's disease.
    Type: Grant
    Filed: September 27, 1999
    Date of Patent: March 6, 2001
    Assignee: Vernalis Research Limited
    Inventors: Allan Fletcher, Lars Jacob Stray Knutsen, Richard H. P. Porter, Scott Murray Weiss, Robin Shepherd