Abstract: A high voltage power supply having energy storage, charging and switching elements and using an interruptible switch as the switching element for efficient, compact and safe operation. In a specific embodiment, the interruptible switch is implemented with at least one cold cathode grid-controlled, crossed field plasma switch and associated control circuit. The charging element is a Marx bank which can be capacitive or inductive. Embodiments with a single master-slave control arrangement, a pulse-forming network providing high voltage regulation, an inductive implementation with a plurality of switching elements in a single envelope with the cathode of at least one switching element being the anode of the next switching element are disclosed. A current amplifier and voltage regulator implemented with a cold cathode grid-controlled, crossed field plasma switch having a cathode, an anode and a control grid therebetween are disclosed.