Abstract: Described herein are coating compositions that can be applied to a number of different substrates. The coating compositions can be used as decorative or protective layers across a range of applications and formulations such as, for example, cosmetics. In one aspect, the coating composition includes a solvent, one or more polymers, and optional additives for enhancing or modifying the properties of the coating composition such as, for example, mechanical properties, rheological properties, appearance, and environmental sensitivity. When applied to the substrate, the coating composition forms a polymer film as the solvent present in the coating composition evaporates. The coating compositions may be easily removed from the substrate with the use of a solvent or a removal solution that reacts or mechanically weakens the film.

Abstract: Described herein is a generalized injection device for delivering formulations of various mechanical properties to precise locations. Of particular interest is the manifestation intended for the application of a thermally responsive hydrogel to the tear duct for the purpose of occlusion, as a treatment for symptoms associated with dry eye syndrome. Further, a modular solution to the need for an injection device across a variety of applications, mechanism, and physical considerations is provided. This disclosure provides examples of methods for precise injection of low volumes, moisture retention in pre-filled injection devices, and actuation for automatic or manual injection, to name a few.

Abstract: A novel glue for embolization of lymphatic leakage. An optimized lymphatic embolization agent (LEA) as described herein comprises a NAM hydrogel and tantalum at a mixture of at or about 1:3 tantalum to NAM hydrogel, wherein said LEA is radiopaque.