Patents by Inventor Robyn Roth

Robyn Roth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITION OF THE ACTIVITY OF KINASE AND SYNTHETASE ENZYMES
    Publication number: 20120270251
    Abstract: The invention provides a method of inhibiting the activity of a kinase or a synthetase, the method including binding an active site of the kinase or synthetase with a deuterated imidazole moiety, thereby inhibiting the activity of the kinase or the synthetase.
    Type: Application
    Filed: December 22, 2010
    Publication date: October 25, 2012
    Applicant: CSIR
    Inventors: Robyn Roth, Colin Peter Kenyon
  • Methods for Obtaining Optically Active Epoxides and Diols from 2,3-Disubstituted and 2,3-Trisubstituted Epoxides
    Publication number: 20080199912
    Abstract: The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific internal epoxide hydrolase activity. The invention also features nucleic acid molecules encoding such polypeptides, vectors containing such nucleic acid molecules, and cells containing such vectors. Also embraced by the invention are methods for obtaining optically active internal epoxides and corresponding optically active internal diols.
    Type: Application
    Filed: October 15, 2007
    Publication date: August 21, 2008
    Applicant: Oxyrane (UK) Ltd.
    Inventors: Adriana Leonora Botes, Jeanette Lotter, Michel Labuschagne, Robin Kumar Mitra, Robyn Roth, Nasreen Abrahams, Clinton Simpson, Christiaan Van Der Westhuyzen
  • Recombinant Yeasts for Synthesizing Epoxide Hydrolases
    Publication number: 20080171359
    Abstract: The invention provides isolated Y. lipolytica cells and substantially pure cultures of Y. lipolytica cells containing exogenous nucleic acids encoding EH polypeptides, e.g., enantioselective EH polypeptides. Also featured by the invention are methods for the production of the EH polypeptides and methods for hydrolysing epoxides and for producing optically active vicinal diols and/or optically active epoxides. Also embodied by the invention are efficient integrative expression vectors.
    Type: Application
    Filed: October 15, 2007
    Publication date: July 17, 2008
    Applicant: Oxyrane (UK) Ltd.
    Inventors: Adriana Leonora Botes, Michel Labuschagne, Robyn Roth, Robin Kumar Mitra, Jeanette Lotter, Rajesh Lalloo, Deepak Ramduth, Neeresh Rohitlall, Clinton Simpson, Petrus Van Zyl