Patents by Inventor Robyn T. Rebbeck

Robyn T. Rebbeck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods to identify modulators of actin-binding proteins
    Patent number: 11656221
    Abstract: The present disclosure provides methods for identifying compounds that cause structural changes in a protein bound to an actin filament. The methods include the use of cells that include two actin-binding proteins, each labeled with a chromophore, and exposing the cells to a test compound. The method further includes detecting a change in fluorescence resonance energy transfer (FRET) between the chromophores.
    Type: Grant
    Filed: June 10, 2020
    Date of Patent: May 23, 2023
    Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Adam William Avery, Thomas S. Hays, David D. Thomas, Michael E. Fealey, Robyn T. Rebbeck
  • METHODS TO IDENTIFY MODULATORS OF ACTIN-BINDING PROTEINS
    Publication number: 20200393445
    Abstract: The present disclosure provides methods for identifying compounds that cause structural changes in a protein bound to an actin filament. The methods include the use of cells that include two actin-binding proteins, each labeled with a chromophore, and exposing the cells to a test compound. The method further includes detecting a change in fluorescence resonance energy transfer (FRET) between the chromophores.
    Type: Application
    Filed: June 10, 2020
    Publication date: December 17, 2020
    Inventors: Adam William Avery, Thomas S. Hays, David D. Thomas, Michael E. Fealey, Robyn T. Rebbeck