Abstract: The present invention provides novel osmium-based electrochemical species for the detection of wide variety of analytes using immunological techniques. The present invention also provides diagnostic kits and test sensors supporting electrode structures that can be used with the osmium-based electrochemical species. The test sensor can be fabricated to support interdigitated arrays of electrodes that have been designed to provide amplification of the electrical signal amplification desired to analyze analytes that may be present at low concentrations.

Abstract: A test element for determining a body fluid is provided. The test element, in particular for determining the blood glucose level, includes a detection region which is charged with a reagent sensitive to the body fluid. A function element is arranged in or adjacent to the detection region for detecting at least one status parameter for the detection region, such that the functional element can be evaluated by means of a status measurement. A method for measuring the test element is also disclosed.

Abstract: A sample rack handling unit comprising an onload section for loading sample racks holding a sample container is presented. The onload section comprises an onload edge and a receiving area with an onload rail longitudinally on the receiving area parallel to the onload edge. The onload rail engages a recess on the rack bottom such that the rack longitudinally slides on the receiving area along the onload rail when the rack is engaged. The onload rail has a base portion and a protrusion extending from the base portion. The protrusion faces the onload edge and the base portion comprises an inclined onload rail side opposite the onload edge such that the recess engages the onload rail when the rack is loaded on the receiving area from the onload edge transversely to the onload rail and the recess disengages the onload rail by sliding the rack towards the onload edge.

Abstract: A device and a method are disclosed for positioning a body part (16) on an analytical device (14) for body fluids includes a flexible compression element (24) for pressing against the body part (16) while increasing the pressure and a rigid support part (26) to hold the compression element (24) on a housing (12) of the analytical device (14). The compression element (24) has an engaging member (34) for the body part (16) which can be pressed into the housing (12) such that a withdrawal region (56) of the body part (16) is exposed in the interior (18) of the housing (12) in order to remove liquid.

Abstract: The present disclosure relates to a luminescence method of detecting an analyte in a liquid sample comprising marking the analyte with a marker capable of effecting luminescence upon application of excitation energy, wherein reference data descriptive of the luminescence decay is stored in an electronic memory; applying the excitation energy for causing the luminescence; time-resolved measuring of the luminescence over a period of time for acquisition of a measurement signal; reading the reference data from the electronic memory; comparing the measurement signal with the luminescence decay described by the reference data; generating an output signal indicative of the presence of the analyte in the liquid sample using the measurement signal; in case of a mismatch of the measurement signal and the luminescence decay described by the reference data, generating an error signal.

Abstract: A device for sampling, transporting and/or disposal of fluid media in the nI and ?l-range comprises a substrate with an open or closed capillary-like groove or channel respectively, the substrate with the open or closed groove or capillary respectively is bent or arcuated at least at one location. The substrate comprises at least one end into which the open or closed capillary-like groove or channel respectively is extended, which end is shaped according to its application or use as e.g. needle-like, straight-lined cut, tip-like, at least most half circle-shape, rounded, etc.

Abstract: A computer-implemented method is provided for a handheld diabetes-management device to establish a data connection with a Continua manager. The method includes: receiving a request to establish a new data connection with a computing device, where the computing device is physically separated from the diabetes-management device and operates as a manager in accordance with IEEE standard 11073; determining whether the diabetes-management device has an existing data connection with a medical device that is physically separated from the diabetes-management device; terminating the existing data connection with the medical device in response to the determination that the diabetes-management device has an existing connection with the medical device; and establishing a new data connection with the computing device in accordance with IEEE standard 11073.

Abstract: An interface for an electronic medical record (EMR) system is configured to receive messages and documents having a message data format and a document data format respectively, transmitted to EMR system in accordance with a first and second device healthcare interoperability standard. The interface is further configured to determine whether a given message or document pertains to blood glucose measures and to generate records in a custom format of the EMR system. The interface is further configured to parse the messages and documents for a structure collection procedure from a comment field in the given messages and documents and to map the structured collection procedure data to applicable data fields in a corresponding record of the EM system.

Abstract: A handheld diabetes manager communicates with an external insulin pump and includes a port for blood glucose measurement, a blood glucose measurement module, a communications module that selectively communicates wirelessly with the insulin pump, and a user interface module. The user interface module communicates with the blood glucose measurement module and the communications module and operates to provide a graphical user interface on a display of the diabetes manager. The graphical user interface includes a personal data menu screen from which a logbook option can be selected to display a logbook screen, and a trend graph option that can be selected to display a trend graph screen. The logbook screen displays a plurality of time data records. Each time data record includes blood glucose data, bolus insulin data, and carbohydrate data for a corresponding time, and a plurality of data icons indicating corresponding events.

Abstract: A handheld diabetes manager has a graphical user interface for displaying status of an external medical device and includes a port configured to receive a test strip and a blood glucose measurement module. The diabetes manager includes a communications module that selectively communicates via a wireless data link with an external medical device to receive status data pertaining to the operation of the external medical device, and a user interface module in data communication with the blood glucose measurement module and the communications module. The graphical user interface includes a status screen that presents data pertaining to a glucose measure determined by the blood glucose measurement module concurrently with the status data received from the external medical device, such that the status data of the external medical device is presented on the status screen only when the communication module is in data communication with the external medical device.

Abstract: A method and an automated system for discriminating bulk liquid from foam and/or residuals of the bulk liquid of a sample contained in a sample vessel are presented. A probe having an electric capacitance is provided and moved into the sample. Consecutive steps of charging and at least partially discharging the probe to generate a discharging current is repeatedly performed. A quantity indicative of the discharging current for the consecutive steps of charging and at least partially discharging the probe is measured. The quantity is analyzed to determine an electric resistance (Rmess) of the sample via the probe. The bulk liquid is discriminated from the foam and/or the residuals of the bulk liquid based on a change of the electric resistance (Rmess) of the sample occurring when the probe contacts the bulk liquid.

Abstract: A handheld diabetes management device is provided which supports preselected meals for improved therapy. The diabetes management device includes: a food database that stores nutritional information for a plurality of food items; a meal selection module that enables a user to preplan meals for a diabetic patient using the food database; and a meal planner module that facilitates use of the preplanned meals to improve therapy for the patient. The diabetes management device further includes an insulin management module that forecasts amounts of insulin needed by a patient over a period of time.

Abstract: A system is provided for withdrawing small amounts of body fluid from an animal or human. The system includes a holder and a disposable lancing unit attached to the holder. The lancing unit also includes an open capillary channel for transporting the body fluid and piercing the skin.

Abstract: A method for producing an analytical consumable is proposed. The analytical consumable comprises at least one carrier and at least one analytical aid connected to the carrier. At least one optically sensitive material is applied to the carrier, said material being designed to carry out at least one optically detectable alteration in the event of action of an electromagnetic radiation. In at least one coding step, at least one function information item about the analytical consumable is introduced into the optically sensitive material by means of electromagnetic radiation. The function information item is designed to enable at least one analytical instrument to use the analytical consumable correctly.

Abstract: This disclosure relates to an analytic test unit for use in a test device for detecting an analyte in a bodily fluid, having at least one test element with a carrier film and a reagent layer, the latter being affixed on the carrier side of the carrier film and it being possible to apply bodily fluid on said reagent layer, wherein the light-transparent carrier film can be positioned in the beam path of a photometric measuring unit for optically scanning the reagent layer. According to this disclosure, it is proposed that the carrier film has a surface, modified by a raised surface structure, for reducing reflections in the beam path of the measuring unit.

Abstract: The present invention relates to a biosensor. The biosensor includes a support substrate, electrodes positioned on the support substrate, a spacer substrate positioned on the support substrate, and a cover positioned on the spacer substrate. The cover cooperates with the support substrate to define a capillary channel. The electrodes include at least one working electrode defining a working electrode area in the capillary channel. The working electrode is configured to minimize variation in the working electrode area in the capillary channel due to variations in the spacer substrate placement relative to the working electrode.

Abstract: A method for at least partially applying a hydrophilic polymer to a measurement channel of a sensor cartridge is provided, which sensor cartridge can be replaceably inserted in an analyzer. The measurement channel comprises at least one sensor element. The method comprises inserting the sensor cartridge into the analyzer, introducing an aqueous solution containing chitosan or a chitosan derivative into the measurement channel of the sensor cartridge, and following a residence time replacing the aqueous chitosan solution with a gaseous or liquid medium, wherein residues of the chitosan or chitosan derivatives remain on the inside surface of the measurement channel and hydrophilize the surface.

Abstract: A method for sterilizing an implantable sensor for sensing an analyte in a body tissue. The implantable sensor has a sensor part which can be introduced into the body tissue, at least one sensor electrode for sensing the analyte, and at least one electronics part. The electronics part has at least one electronic component and is connected to the sensor part. The method includes (a) introducing the implantable sensor into a package, the package sealing the implantable sensor from bacteria and accommodating a radiation shield, (b) irradiating the implantable sensor in the package with sterilizing radiation from at least one irradiating direction, in particular with electron radiation, the radiation shield shielding the electronic component of the electronics part from the sterilizing radiation, the radiation shield being arranged in such a way that the sensor part is sterilized by the sterilizing radiation.

Abstract: A diabetes care kit for providing diagnostics and therapy that is preconfigured to reduce initial setup by a user. The kit can include a handheld diabetes managing device and insulin pump. The handheld diabetes managing device and insulin pump can each be preloaded with an encryption key such that the handheld diabetes managing device and the insulin pump are paired and a secure bidirectional communication link exists between the handheld diabetes managing device and the insulin pump.

Abstract: A system and method for considering the effects of aerobic exercise on blood glucose levels for individuals is described. In at least one embodiment of the system of the present disclosure, the system comprises a computing device for generating a prediction of future blood glucose levels for the individual at least partly based on an exercise model, wherein the exercise model is based on parameters that are independent of intensity of the aerobic exercise, and a means for taking an action at least based on the prediction from the exercise model.