Patents by Inventor Rock J. Mancini

Rock J. Mancini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stabilization of biomolecules using sugar polymers
    Patent number: 10543280
    Abstract: Compositions and methods for stabilizing biomolecules are disclosed. Specifically, the compositions include novel homopolymers or copolymers containing trehalose side chains conjugated to biomolecules. When such homopolymers or copolymers are placed in close proximity to biomolecules, such as proteins, the homopolymers or copolymers protect and/or stabilize the biomolecule. The compositions and methods may be suitable for use in various industries such as healthcare (pharmaceuticals), molecular biology, biofuels, paper, personal care, detergent, photographic, rubber, brewing, dairy and food processing industries.
    Type: Grant
    Filed: January 29, 2018
    Date of Patent: January 28, 2020
    Assignee: The Regents of the University of California
    Inventors: Heather D. Maynard, Rock J. Mancini, Juneyoung Lee, En-Wei Lin
  • STABILIZATION OF BIOMOLECULES USING SUGAR POLYMERS
    Publication number: 20190125885
    Abstract: Compositions and methods for stabilizing biomolecules are disclosed. Specifically, the compositions include novel homopolymers or copolymers containing trehalose side chains conjugated to biomolecules. When such homopolymers or copolymers are placed in close proximity to biomolecules, such as proteins, the homopolymers or copolymers protect and/or stabilize the biomolecule. The compositions and methods may be suitable for use in various industries such as healthcare (pharmaceuticals), molecular biology, biofuels, paper, personal care, detergent, photographic, rubber, brewing, dairy and food processing industries.
    Type: Application
    Filed: January 29, 2018
    Publication date: May 2, 2019
    Inventors: Heather D. Maynard, Rock J. Mancini, Juneyoung Lee, En-Wei Lin
  • Stabilization of biomolecules using sugar polymers
    Patent number: 9901648
    Abstract: Compositions and methods for stabilizing biomolecules are disclosed. Specifically, the compositions include novel homopolymers or copolymers containing trehalose side chains conjugated to biomolecules. When such homopolymers or copolymers are placed in close proximity to biomolecules, such as proteins, the homopolymers or copolymers protect and/or stabilize the biomolecule. The compositions and methods may be suitable for use in various industries such as healthcare (pharmaceuticals), molecular biology, biofuels, paper, personal care, detergent, photographic, rubber, brewing, dairy and food processing industries.
    Type: Grant
    Filed: January 25, 2013
    Date of Patent: February 27, 2018
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Heather D. Maynard, Rock J. Mancini, Juneyoung Lee, En-Wei Lin
  • NOVEL IMMUNOSTIMULANTS AND SYNTHESIS THEREOF
    Publication number: 20150050313
    Abstract: Disclosed herein are heteromeric molecules comprising two or more different pathogen associated molecular patterns (PAMPs), wherein the two or more PAMPs are linked together with discrete, linear inter-PAMP spacing. Also disclosed are immunogenic compositions comprising the heteromeric molecules and related methods of stimulating an immune response in vivo in a subject or ex vivo comprising administering the immunogenic composition to cells. Also disclosed is a method of synthesizing an immunostimulant comprising: identifying 2 or more different PAMPS, covalently linking the 2 or more different PAMPS together, varying spacing between the 2 or more different PAMPs, and testing the effect of spacing between the 2 or more different PAMPS to identify an optimal spacing that results in immune stimulation.
    Type: Application
    Filed: August 13, 2014
    Publication date: February 19, 2015
    Inventors: Rock J. Mancini, Janine K. Tom, Aaron P. Esser-Kahn
  • STABILIZATION OF BIOMOLECULES USING SUGAR POLYMERS
    Publication number: 20140377838
    Abstract: Compositions and methods for stabilizing biomolecules are disclosed. Specifically, the compositions include novel homopolymers or copolymers containing trehalose side chains conjugated to biomolecules. When such homopolymers or copolymers are placed in close proximity to biomolecules, such as proteins, the homopolymers or copolymers protect and/or stabilize the biomolecule. The compositions and methods may be suitable for use in various industries such as healthcare (pharmaceuticals), molecular biology, biofuels, paper, personal care, detergent, photographic, rubber, brewing, dairy and food processing industries.
    Type: Application
    Filed: January 25, 2013
    Publication date: December 25, 2014
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Heather D. Maynard, Rock J. Mancini, Juneyoung Lee, En-Wei Lin