Patents by Inventor Roderick G. Flemming

Roderick G. Flemming has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Functionalized NANOLUC inhibitors
    Patent number: 10815247
    Abstract: Compounds that may inhibit Oplophorus-derived luciferases are disclosed as well as compositions and kits comprising the compounds, and methods of using the compounds.
    Type: Grant
    Filed: December 28, 2017
    Date of Patent: October 27, 2020
    Assignee: PROMEGA CORPORATION
    Inventors: Roderick G. Flemming, Mary Hall, Thomas Machleidt, Poncho Meisenheimer, Nidhi Nath, Matthew B. Robers, Joel R. Walker, Wenhui Zhou
  • FUNCTIONALIZED NANOLUC INHIBITORS
    Publication number: 20180222916
    Abstract: Compounds that may inhibit Oplophorus-derived luciferases are disclosed as well as compositions and kits comprising the compounds, and methods of using the compounds.
    Type: Application
    Filed: December 28, 2017
    Publication date: August 9, 2018
    Inventors: Roderick G. Flemming, Mary Hall, Thomas Machleidt, Poncho Meisenheimer, Nidhi Nath, Matthew B. Robers, Joel R. Walker, Wenhui Zhou
  • Methods for separating molecules
    Patent number: 7354750
    Abstract: The present invention provides compositions and methods for the separation of metals or molecules such as polypeptides, nucleic acids, or endotoxins using a metal-modified solid support. The metals or molecules are isolated from a starting material using the modified solid supports of the invention. Also provided by the invention are kits that can be used in connection with the inventive methods.
    Type: Grant
    Filed: October 20, 2003
    Date of Patent: April 8, 2008
    Assignee: Promega Corporation
    Inventors: Daniel J. Simpson, Tonny Johnson, John Shultz, Roderick G. Flemming, Rebecca Godat, Sanchayita Kar, Robin Hurst
  • Compositions for separating molecules
    Patent number: 7304016
    Abstract: The present invention provides compositions for the separation of metals or biomolecules such as polypeptides, nucleic acids, or endotoxins using modified solid supports.
    Type: Grant
    Filed: May 19, 2006
    Date of Patent: December 4, 2007
    Assignee: Promega Corporation
    Inventors: Daniel J. Simpson, Tonny M. Johnson, Roderick G. Flemming
  • Compositions for separating molecules
    Patent number: 7304015
    Abstract: The present invention provides compositions for the separation of metals or biomolecules such as polypeptides, nucleic acids, or endotoxins using modified solid supports.
    Type: Grant
    Filed: August 11, 2005
    Date of Patent: December 4, 2007
    Assignee: Promega Corporation
    Inventors: Daniel J. Simpson, Tonny Johnson, Roderick G. Flemming
  • Compositions for separating molecules
    Patent number: 7112552
    Abstract: The present invention provides compositions for the separation of metals or biomolecules such as polypeptides, nucleic acids, or endotoxins using modified solid supports.
    Type: Grant
    Filed: October 20, 2003
    Date of Patent: September 26, 2006
    Assignee: Promega Corporation
    Inventors: Daniel J. Simpson, Tonny Johnson, Roderick G. Flemming
  • Methods for separating molecules
    Publication number: 20040185545
    Abstract: The present invention provides compositions and methods for the separation of metals or molecules such as polypeptides, nucleic acids, or endotoxins using a metal-modified solid support. The metals or molecules are isolated from a starting material using the modified solid supports of the invention. Also provided by the invention are kits that can be used in connection with the inventive methods.
    Type: Application
    Filed: October 20, 2003
    Publication date: September 23, 2004
    Applicant: Promega Corporation
    Inventors: Daniel J. Simpson, Tonny Johnson, John Shultz, Roderick G. Flemming, Rebecca Godat, Sanchayita Kar, Robin Hurst
  • Lysate clearance and nucleic acid isolation using silanized silica matrices
    Patent number: 6787307
    Abstract: A method is provided for using a silanized silica matrix to isolate a target nucleic acids, such as plasmid DNA, fragments of DNA, chromosomal DNA, or RNA from contaminants, including proteins, lipids, cellular debris, or non-target nucleic acids. The silanized silica matrix comprises a silica based solid phase and a plurality of silane ligands covalently attached to the surface of the solid phase. Non-target material adsorbs to the silanized silica matrix in the presence of a sufficient concentration of chaotropic salt, while target nucleic acids adsorb to the matrix under other solution conditions. The method of using the silanized silica matrix of the present invention can be used to clear solutions of disrupted biological material, and to isolate nucleic acids therefrom or from other solutions containing nucleic acids and at least one contaminant.
    Type: Grant
    Filed: November 13, 2000
    Date of Patent: September 7, 2004
    Assignee: Promega Corporation
    Inventors: Rex M. Bitner, Daniel J. Simpson, Roderick G. Flemming, Susan C. Koller
  • Compositions for separating molecules
    Publication number: 20040127357
    Abstract: The present invention provides compositions for the separation of metals or biomolecules such as polypeptides, nucleic acids, or endotoxins using modified solid supports.
    Type: Application
    Filed: October 20, 2003
    Publication date: July 1, 2004
    Applicant: Promega Corporation
    Inventors: Daniel J. Simpson, Tonny Johnson, Roderick G. Flemming