Patents by Inventor Roderick J. Ray

Roderick J. Ray has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYSTEMS AND METHODS FOR PRODUCING BIOPRODUCTS
    Publication number: 20210047606
    Abstract: The present disclosure is directed to systems and methods for sampling and/or controlling the productivity of a bioreactor. The system and methods can include a vessel capable of providing an environment suitable for containing whole broth that can produce the bioproduct, wherein the whole broth contains media and at least one undissolved species, an automated sampling system, a first analytical instrument, and a control system.
    Type: Application
    Filed: October 30, 2020
    Publication date: February 18, 2021
    Applicant: Bend Research, Inc.
    Inventors: Roderick J. Ray, Adam S. Carroll, Brandon J. Downey, Lisa J. Graham
  • Systems and methods for producing bioproducts
    Patent number: 10836991
    Abstract: The present disclosure is directed to systems and methods for sampling and/or controlling the productivity of a bioreactor. The system and methods can include a vessel capable of providing an environment suitable for containing whole broth that can produce the bioproduct, wherein the whole broth contains media and at least one undissolved species, an automated sampling system, a first analytical instrument, and a control system.
    Type: Grant
    Filed: August 30, 2019
    Date of Patent: November 17, 2020
    Assignee: Bend Research, Inc.
    Inventors: Roderick J. Ray, Adam S. Carroll, Brandon J. Downey, Lisa J. Graham
  • SYSTEMS AND METHODS FOR PRODUCING BIOPRODUCTS
    Publication number: 20200017818
    Abstract: The present disclosure is directed to systems and methods for sampling and/or controlling the productivity of a bioreactor. The system and methods can include a vessel capable of providing an environment suitable for containing whole broth that can produce the bioproduct, wherein the whole broth contains media and at least one undissolved species, an automated sampling system, a first analytical instrument, and a control system.
    Type: Application
    Filed: August 30, 2019
    Publication date: January 16, 2020
    Applicant: Bend Research, Inc.
    Inventors: Roderick J. Ray, Adam S. Carroll, Brandon J. Downey, Lisa J. Graham
  • Systems and methods for producing bioproducts
    Patent number: 10421939
    Abstract: The present disclosure is directed to systems and methods for sampling and/or controlling the productivity of a bioreactor.
    Type: Grant
    Filed: October 24, 2012
    Date of Patent: September 24, 2019
    Assignee: Bend Research, Inc.
    Inventors: Roderick J. Ray, Adam S. Carroll, Brandon J. Downey, Lisa J. Graham
  • Pharmaceutical dosage forms comprising a low-solubility drug and a polymer
    Patent number: 9445998
    Abstract: A dosage form comprises a low-solubility drug, and a precipitation-inhibiting polymer. The drug is in a solubility-improved form and in the form of particles at least partially coated with the precipitation-inhibiting polymer.
    Type: Grant
    Filed: November 7, 2014
    Date of Patent: September 20, 2016
    Assignee: Bend Research, Inc.
    Inventors: Leah E. Appel, Walter C. Babcock, Dwayne T. Friesen, Roderick J. Ray, Daniel T. Smithey, Sheri L. Shamblin, Ravi M. Shanker
  • Method for making homogeneous spray-dried solid amorphous drug dispersions utilizing modified spray-drying apparatus
    Patent number: 9339467
    Abstract: Conventional spray-drying methods are improved by incorporation of a pressure nozzle and a diffuser plate to improve the flow of drying gas and a drying chamber extension to increase drying time, such improvements leading to the formation of homogeneous solid dispersions of drugs in concentration-enhancing polymers.
    Type: Grant
    Filed: August 5, 2014
    Date of Patent: May 17, 2016
    Assignee: Bend Research, Inc.
    Inventors: Ronald A. Beyerinck, Heather L. M. Deibele, Dan E. Dobry, Roderick J. Ray, Dana M. Settell, Ken R. Spence
  • PHARMACEUTICAL DOSAGE FORMS COMPRISING A LOW-SOLUBILITY DRUG AND A POLYMER
    Publication number: 20150064264
    Abstract: A dosage form comprises a low-solubility drug, and a precipitation-inhibiting polymer. The drug is in a solubility-improved form and in the form of particles at least partially coated with the precipitation-inhibiting polymer.
    Type: Application
    Filed: November 7, 2014
    Publication date: March 5, 2015
    Applicant: Bend Research, Inc.
    Inventors: Leah E. Appel, Walter C. Babcock, Dwayne T. Friesen, Roderick J. Ray, Daniel T. Smithey, Sheri L. Shamblin, Ravi M. Shanker
  • METHOD FOR MAKING HOMOGENEOUS SPRAY-DRIED SOLID AMORPHOUS DRUG DISPERSIONS UTILIZING MODIFIED SPRAY-DRYING APPARATUS
    Publication number: 20150028503
    Abstract: Conventional spray-drying methods are improved by incorporation of a pressure nozzle and a diffuser plate to improve the flow of drying gas and a drying chamber extension to increase drying time, such improvements leading to the formation of homogeneous solid dispersions of drugs in concentration-enhancing polymers.
    Type: Application
    Filed: August 5, 2014
    Publication date: January 29, 2015
    Applicant: BEND RESEARCH, INC.
    Inventors: Ronald A. Beyerinck, Heather L. M. Deibele, Dan E. Dobry, Roderick J. Ray, Dana M. Settell, Ken R. Spence
  • SYSTEMS AND METHODS FOR PRODUCING BIOPRODUCTS
    Publication number: 20140295532
    Abstract: The present disclosure is directed to systems and methods for sampling and/or controlling the productivity of a bioreactor.
    Type: Application
    Filed: October 24, 2012
    Publication date: October 2, 2014
    Applicant: Bend Research, Inc.
    Inventors: Roderick J. Ray, Adam S. Carroll, Brandon J. Downey, Lisa J. Graham
  • Method for making homogeneous spray-dried solid amorphous drug dispersions utilizing modified spray-drying apparatus
    Patent number: 8828443
    Abstract: Conventional spray-drying methods are improved by incorporation of a pressure nozzle and a diffuser plate to improve the flow of drying gas and a drying chamber extension to increase drying time, such improvements leading to the formation of homogeneous solid dispersions of drugs in concentration-enhancing polymers.
    Type: Grant
    Filed: December 26, 2012
    Date of Patent: September 9, 2014
    Assignee: Bend Research, Inc.
    Inventors: Ronald A. Beyerinck, Heather L. M. Diebele, Dan E. Dobry, Roderick J. Ray, Dana M. Settell, Ken R. Spence
  • Method for making homogeneous spray-dried solid amorphous drug dispersions utilizing modified spray-drying apparatus
    Patent number: 8343550
    Abstract: Conventional spray-drying methods are improved by incorporation of a pressure nozzle and a diffuser plate to improve the flow of drying gas and a drying chamber extension to increase drying time, such improvements leading to the formation of homogeneous solid dispersions of drugs in concentration-enhancing polymers.
    Type: Grant
    Filed: June 21, 2011
    Date of Patent: January 1, 2013
    Assignee: Bend Research, Inc.
    Inventors: Ronald A. Beyerinck, Heather L. M. Deibele, Dan E. Dobry, Roderick J. Ray, Dana M. Settell, Ken R. Spence
  • METHOD FOR MAKING HOMOGENEOUS SPRAY-DRIED SOLID AMORPHOUS DRUG DISPERSIONS UTILIZING MODIFIED SPRAY-DRYING APPARATUS
    Publication number: 20110277339
    Abstract: Conventional spray-drying methods are improved by incorporation of a pressure nozzle and a diffuser plate to improve the flow of drying gas and a drying chamber extension to increase drying time, such improvements leading to the formation of homogeneous solid dispersions of drugs in concentration-enhancing polymers.
    Type: Application
    Filed: June 21, 2011
    Publication date: November 17, 2011
    Inventors: Ronald A. Beyerinck, Heather L. M. Deibele, Dan E. Dobry, Roderick J. Ray, Dana M. Settell, Ken R. Spence
  • Method of making pharmaceutical multiparticulates
    Patent number: 7951403
    Abstract: A process for forming drug multiparticulates having improved drug crystallinity is disclosed, comprising modifying a conventional melt-congeal process by adding a volatile cospecies either to the molten mixture or to the process atmosphere, or to both.
    Type: Grant
    Filed: December 3, 2004
    Date of Patent: May 31, 2011
    Assignee: Pfizer Inc.
    Inventors: Dwayne T. Friesen, Marshall D. Crew, Roderick J. Ray, Leah E. Appel
  • Multiparticulate crystalline drug compositions having controlled release profiles
    Patent number: 7887844
    Abstract: A multiparticulate for controlled release of a drug comprises crystalline drug, a glyceride having at least one alkylate substituent of at least 16 carbon atoms, and a poloxamer, wherein at least 70 wt % of the drug in the multiparticulate is crystalline.
    Type: Grant
    Filed: December 3, 2004
    Date of Patent: February 15, 2011
    Assignee: Pfizer Inc.
    Inventors: Leah E. Appel, Roderick J. Ray, David K. Lyon, James B. West, Scott B. McCray, Marshall D. Crew, Dwayne T. Friesen, Scott M. Herbig, Julian B. Lo
  • Method for making homogeneous spray-dried solid amorphous drug dispersions using pressure nozzles
    Patent number: 7780988
    Abstract: Homogeneous solid amorphous dispersions of drugs in concentration-enhancing polymers are formed in desirable larger particle sizes with minimal fines by using an atomizer and process conditions capable of producing droplets having an average diameter of at least 50 microns and a D10 of at least 10 microns.
    Type: Grant
    Filed: January 24, 2003
    Date of Patent: August 24, 2010
    Assignee: Bend Research, Inc.
    Inventors: Ronald A. Beyerinck, Roderick J. Ray, Dan E. Dobry, Dana M. Settell
  • Multiparticulate compositions with improved stability
    Patent number: 7736672
    Abstract: A process is described for producing drug-containing multiparticulates with improved stability, characterized by an improvement in one or more of chemical stability, physical stability, or dissolution stability.
    Type: Grant
    Filed: December 3, 2004
    Date of Patent: June 15, 2010
    Assignee: Pfizer, Inc.
    Inventors: Roderick J. Ray, Leah E. Appel, Dwayne Thomas Friesen, Marshall D. Crew, Joshua R. Shockey
  • Extrusion process for forming chemically stable drug multiparticulates
    Patent number: 7625507
    Abstract: Reduced levels of drug degradation in drug-containing multiparticulates are obtained by an extrusion/melt-congeal process.
    Type: Grant
    Filed: December 3, 2004
    Date of Patent: December 1, 2009
    Assignee: Pfizer Inc.
    Inventors: Roderick J. Ray, Leah E. Appel, David D. Newbold, Dwayne T. Friesen, Scott B. McCray, David K. Lyon, James B. West, Marshall D. Crew, Joshua R. Shockey
  • PHARMACEUTICAL DOSAGE FORMS COMPRISING A LOW-SOLUBILITY DRUG AND A POLYMER
    Publication number: 20090142404
    Abstract: A dosage form comprises a low-solubility drug, and a precipitation-inhibiting polymer. The drug is in a solubility-improved form and in the form of particles at least partially coated with the precipitation-inhibiting polymer. Exemplified low-solubility drugs are ziprasidone and sildenafil. Exemplified precipitation-inhibiting polymer is HPMCAS.
    Type: Application
    Filed: August 18, 2005
    Publication date: June 4, 2009
    Inventors: Leah E. Appel, Walter C. Babcock, Dwayne T. Friesen, Roderick J. Ray, Daniel T. Smithey, Sheri L. Shamblin, Ravi M. Shanker
  • Solvent-resistant microporous polybenzimidazole membranes and modules
    Patent number: 6986844
    Abstract: Solvent-resistant polybenzimidazole membranes, methods of making them and crosslinking them and composite membranes and hollow fiber membrane modules from them are disclosed.
    Type: Grant
    Filed: June 27, 2003
    Date of Patent: January 17, 2006
    Assignee: Bend Research, Inc.
    Inventors: Robert P. Barss, Dwayne T. Friesen, Scott B. McCray, Kendall R. Pearson, Roderick J. Ray, Delores R. Sidwell, James B. West
  • Method for making homogeneous spray-dried solid amorphous drug dispersions utilizing modified spray-drying apparatus
    Patent number: 6973741
    Abstract: Conventional spray-drying methods are improved by incorporation of a pressure nozzle and a diffuser plate to improve the flow of drying gas and a drying chamber extension to increase drying time, such improvements leading to the formation of homogeneous solid dispersions of drugs in concentration-enhancing polymers.
    Type: Grant
    Filed: January 27, 2004
    Date of Patent: December 13, 2005
    Assignee: Pfizer, Inc.
    Inventors: Ronald A. Beyerinck, Heather L. M. Diebele, Dan E. Dobry, Roderick J. Ray, Dana M. Settell, Ken R. Spence