Patents by Inventor Rodger Smith

Rodger Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rapid nucleic acid assay
    Publication number: 20050181430
    Abstract: This invention relates to an improved process for detecting and quantifying a desired nucleic acid sequence. The process involves synthesizing single stranded RNA, single stranded DNA, double-stranded DNA followed by detection using an electrochemiluminescent labeled binding species.
    Type: Application
    Filed: March 28, 2005
    Publication date: August 18, 2005
    Applicant: BioVeris Corporation
    Inventors: John Kenten, Rodger Smith
  • Prodrugs activated by targeted catalytic proteins
    Publication number: 20050123533
    Abstract: Disclosed and claimed are prodrugs activated by catalytic proteins, such as enzymes and catalytic antibodies. The invention comprehends such prodrugs, as well as haptens, to elicit catalytic antibodies to activate the prodrugs. The prodrugs are useful as cytotoxic chemotherapeutic agents; e.g., as antitumor agents.
    Type: Application
    Filed: November 3, 2003
    Publication date: June 9, 2005
    Inventors: John Kenten, Reid Borstel, Jan Casadei, Balreddy Kamireddy, Mark Martin, Richard Massey, Andrew Napper, David Simpson, Rodger Smith, Richard Titmas, Richard Williams
  • Cycling DNA/RNA amplification electrochemiluminescent probe assay
    Patent number: 6890712
    Abstract: This invention relates to an improved process for detecting and quantifying a desired nucleic acid sequence. The process involves synthesizing single stranded RNA, single stranded DNA, double-stranded DNA followed by detection using an electrochemiluminescent labeled binding species.
    Type: Grant
    Filed: January 10, 2000
    Date of Patent: May 10, 2005
    Assignee: BioVeris Corporation
    Inventors: John H. Kenten, Rodger Smith
  • Prodrugs activated by targeted catalytic proteins
    Patent number: 6702705
    Abstract: Catalytic antibodies are disclosed. The catalytic antibodies are specific for prodrug compounds. The catalytic antibodies enhance cleavage of an active drug moiety from a prodrug residue, thereby activating the drug.
    Type: Grant
    Filed: February 22, 1995
    Date of Patent: March 9, 2004
    Assignee: IGEN International, Inc.
    Inventors: Reid von Borstel, Jan M. Casadei, Balreddy Kamireddy, John Kenten, Mark T. Martin, Richard J. Massey, Andrew D. Napper, David M. Simpson, Rodger Smith, Richard C. Titmas, Richard O. Williams
  • Cycling DNA/RNA amplification electrochemiluminescent probe assay
    Patent number: 6048687
    Abstract: This invention relates to an improved process for detecting and quantifying a desired nucleic acid sequence. The process involves synthesizing single stranded RNA, single stranded DNA, double-stranded DNA followed by detection using an electrochemiluminescent labeled binding species.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: April 11, 2000
    Assignee: IGEN International, Inc.
    Inventors: John H. Kenten, Rodger Smith
  • Isolation and production of catalytic antibodies using phage technology
    Patent number: 5855885
    Abstract: Disclosed and claimed are methods for producing catalytic antibodies, including human catalytic antibodies, from bacteriophage. The methods require the cloning, selection, screening, and isolation of catalytic antibodies. Also disclosed and claimed are the products themselves, the catalytic antibodies, made from the phage technology. In addition, catalytic antibodies produced from the phage technology and useful in prodrug activation are disclosed and claimed. And finally, the invention also understands the production of catalytic antibodies to phosphonates.
    Type: Grant
    Filed: July 14, 1994
    Date of Patent: January 5, 1999
    Inventors: Rodger Smith, John McCafferty, David Chiswell, Michael J. Darsley, Kevin Fitzgerald, John H. Kenten, Mark T. Martin, Richard C. Titmas, Richard O. Williams