Patents by Inventor Rodney Hewick

Rodney Hewick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies to natural killer stimulatory factor
    Publication number: 20070104680
    Abstract: This application relates to antibodies reactive with a novel homogenous human cytokine, Natural Killer Stimulator Factor (NKSF), having the ability to induce the production of gamia interferon in vitro in human peripheral blood lymphocytes, and a pharmaceutical preparation containing such antibodies.
    Type: Application
    Filed: August 16, 2006
    Publication date: May 10, 2007
    Inventors: Giorgio Trinchieri, Bice Perussia, Stanley Wolf, Steven Clark, Gordon Wong, Rodney Hewick, Michiko Kobayashi
  • Natural killer stimulatory factor
    Patent number: 7122633
    Abstract: This application relates to antibodies reactive with a novel homogenous human cytokine, Natural Killer Stimulator Factor (NKSF), having the ability to induce the production of gamma interferon in vitro in human peripheral blood lymphocytes, and a pharmaceutical preparation containing such antibodies.
    Type: Grant
    Filed: February 5, 2003
    Date of Patent: October 17, 2006
    Assignees: The Wistar Institute, Wyeth
    Inventors: Giorgio Trinchieri, Bice Perussia, Stanley F. Wolf, Steven C. Clark, Gordon G. Wong, Rodney Hewick, Michiko Kobayashi
  • Megakaryocyte stimulating factors
    Publication number: 20060025570
    Abstract: Novel polypeptides of human megakaryocyte stimulating factors (MSFs). Pharmaceutical compositions containing same, and methods for their preparation and use are provided.
    Type: Application
    Filed: June 28, 2005
    Publication date: February 2, 2006
    Inventors: Katherine Turner, Steven Clark, Kenneth Jacobs, Rodney Hewick, Thomas Gesner
  • Acid-labile isotope-coded extractant (ALICE) and its use in quantitative mass spectrometric analysis of protein mixtures
    Publication number: 20050014278
    Abstract: The method of the invention provides novel compounds, termed acid-labile isotope-coded extractants (ALICE), for quantitative mass spectrometric analysis of protein mixtures. The compounds contain a thiol-reactive group that is used to capture cysteine-containing peptides from all peptide mixtures, an acid-labile linker, and a non-biological polymer. One of the two acid-labile linkers is isotopically labeled and therefore enables the direct quantitation of peptides/proteins through mass spectrometric analysis. Because no functional proteins are required to capture peptides, a higher percentage of organic solvent can be used to solubilize the peptides, particularly hydrophobic peptides, through the binding, washing and eluting steps, thus permitting much better recover of peptides. Moreover, since the peptides are covalently linked to the non-biological polymer (ALICE), more stringent washing is allowed in order to completely remove non-specifically bound species.
    Type: Application
    Filed: August 17, 2004
    Publication date: January 20, 2005
    Inventors: Yongchang Qiu, Jack Wang, Rodney Hewick
  • Antibodies to natural killer stimulatory factor
    Publication number: 20040044186
    Abstract: This application relates to antibodies reactive with a novel homogenous human cytokine, Natural Killer Stimulator Factor (NKSF), having the ability to induce the production of gamma interferon in vitro in human peripheral blood lymphocytes, and a pharmaceutical preparation containing such antibodies.
    Type: Application
    Filed: February 5, 2003
    Publication date: March 4, 2004
    Applicant: Wyeth and The Wistar Institute
    Inventors: Giorgio Trinchieri, Bice Perussia, Stanley F. Wolf, Steven C. Clark, Gordon G. Wong, Rodney Hewick, Michiko Kobayashi
  • Antibodies to natural killer stimulatory factor
    Patent number: 6555658
    Abstract: This application relates to antibodies reactive with a novel homogenous human cytokine, Natural Killer Stimulator Factor (NKSF), having the ability to induce the production of gamma interferon in vitro in human peripheral blood lymphocytes, and a pharmaceutical preparation containing such antibodies.
    Type: Grant
    Filed: August 9, 2001
    Date of Patent: April 29, 2003
    Assignees: Wyeth, The Wistar Institute
    Inventors: Giorgio Trinchieri, Bice Perussia, Steven C. Clark, Gordon G. Wong, Rodney Hewick, Michiko Kobayashi
  • Antibodies to natural killer stimulatory factor
    Patent number: 6300478
    Abstract: Antibodies reactive with a novel homogeneous human cytokine, Natural Killer Stimulatory Factor, (NKSF), NKSF having the ability to induce the production of gamma interferon in vitro in human peripheral blood lymphocytes, and a pharmaceutical preparation containing such antibodies.
    Type: Grant
    Filed: June 4, 1999
    Date of Patent: October 9, 2001
    Assignee: Genetics Institute, Inc.
    Inventors: Giorgio Trinchieri, Bice Perussia, Steven C. Clark, Gordon G. Wong, Rodney Hewick, Michiko Kobayashi
  • Antibodies to natural killer stimulatory factor
    Patent number: 5811523
    Abstract: A novel homogeneous human cytokine, Natural Killer Stimulatory Factor, having the ability to induce the production of gamma interferon in vitro in human peripheral blood lymphocytes, and a pharmaceutical preparation containing it.
    Type: Grant
    Filed: October 22, 1997
    Date of Patent: September 22, 1998
    Inventors: Giorgio Trinchieri, Bice Perussia, Steven C. Clark, Gordon G. Wong, Rodney Hewick, Michiko Kobayashi, Stanley F. Wolf
  • Natural killer cell stimulatory factor
    Patent number: 5648467
    Abstract: A novel homogeneous human cytokine, Natural Killer Stimulatory Factor, having the ability to induce the production of gamma interferon in vitro in human peripheral blood lymphocytes, and a pharmaceutical preparation containing it.
    Type: Grant
    Filed: March 13, 1995
    Date of Patent: July 15, 1997
    Assignee: Genetics Institute, Inc.
    Inventors: Giorgio Trinchieri, Bice Perussia, Steven C. Clark, Gordon G. Wong, Rodney Hewick, Michiko Kobayashi, Stanley F. Wolf
  • Methods of inducing gamma interferon and stimulating blood cell populations using natural killer stimulatory factor
    Patent number: 5648072
    Abstract: Methods of inducing gamma interferon production and stimulating lymphocyte populations using Natural Killer Stimulatory Factor (NKSF) are disclosed.
    Type: Grant
    Filed: March 13, 1995
    Date of Patent: July 15, 1997
    Assignee: Genetics Institute, Inc.
    Inventors: Giorgio Trinchieri, Bice Perussia, Steven C. Clark, Michiko Kobayashi, Gordon G. Wong, Rodney Hewick, Stanley F. Wolf
  • Methods of treating infection using natural killer stimulatory factor
    Patent number: 5569454
    Abstract: Methods of treating an infection using Natural Killer Stimulatory Factor (NKSF) are disclosed.
    Type: Grant
    Filed: March 13, 1995
    Date of Patent: October 29, 1996
    Assignee: Genetics Institute, Inc.
    Inventors: Giorgio Trinchieri, Bice Perussia, Steven C. Clark, Gordon G. Wong, Rodney Hewick, Michiko Kobayashi, Stanley F. Wolf
  • Natural killer stimulatory factor
    Patent number: 5457038
    Abstract: A novel homogeneous human cytokine, Natural Killer Stimulatory Factor, having the ability to induce the production of gamma interferon in vitro in human peripheral blood lymphocytes, and a pharmaceutical preparation containing it.
    Type: Grant
    Filed: September 18, 1990
    Date of Patent: October 10, 1995
    Assignee: Genetics Institute, Inc.
    Inventors: Giorgio Trinchieri, Bice Perussia, Michiko Kobayashi, Steven C. Clark, Gordon G. Wong, Rodney Hewick