Patents by Inventor Rodney M. Camire

Rodney M. Camire has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods for Modulating Factor IX Function
    Publication number: 20230250412
    Abstract: Factor IX/IXa variants and methods of use thereof are disclosed.
    Type: Application
    Filed: March 1, 2023
    Publication date: August 10, 2023
    Inventors: Valder R. Arruda, Rodney M. Camire, Benjamin Samelson-Jones
  • Compositions and methods for modulating Factor IX function
    Patent number: 11708570
    Abstract: Factor IX/IXa variants and methods of use thereof are disclosed.
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: July 25, 2023
    Assignee: THE CHILDREN'S HOSPITAL OF PHILADELPHIA
    Inventors: Valder R. Arruda, Rodney M. Camire, Benjamin Samelson-Jones
  • COMPOSITIONS AND METHODS FOR MODULATING FACTOR VIII FUNCTION
    Publication number: 20220403005
    Abstract: Factor VIII variants and methods of use thereof are disclosed. In accordance with the present invention, compositions and methods for the modulation of hemostasis in patients in need thereof are provided. More specifically. Factor VIII (FVIII) variants which modulate (e.g., increase) hemostasis are provided. In a particular embodiment, the Factor VIII variant comprises at least one mutation at position 336 and/or 562.
    Type: Application
    Filed: December 7, 2020
    Publication date: December 22, 2022
    Inventors: Lindsey A. George, Rodney M. Camire
  • COMPOSITIONS AND METHODS FOR COUNTERACTING FACTOR XA INHIBITION
    Publication number: 20210000930
    Abstract: The disclosure provides compositions and methods for counteracting the effects of direct activated Factor X (FXa) inhibitors in a subject by administering a variant of FXa.
    Type: Application
    Filed: March 16, 2020
    Publication date: January 7, 2021
    Inventors: Debra D. Pittman, Rodney M. Camire, Joachim Fruebis
  • Compositions and Methods for Modulating Factor IX Function
    Publication number: 20200248161
    Abstract: Factor IX/IXa variants and methods of use thereof are disclosed.
    Type: Application
    Filed: July 27, 2017
    Publication date: August 6, 2020
    Inventors: Valder R. Arruda, Rodney M. Camire, Benjamin Samelson-Jones
  • Compositions and methods for modulating factor IX function
    Patent number: 10676731
    Abstract: Factor IX/IXa variants and methods of use thereof are disclosed.
    Type: Grant
    Filed: August 19, 2015
    Date of Patent: June 9, 2020
    Assignee: THE CHILDREN'S HOSPITAL OF PHILADELPHIA
    Inventors: Rodney M. Camire, Lacramioara Ivanciu, Valder R. Arruda
  • Compositions and methods for counteracting Factor Xa inhibition
    Patent number: 10588950
    Abstract: The disclosure provides compositions and methods for counteracting the effects of direct activated Factor X (FXa) inhibitors in a subject by administering a variant of FXa.
    Type: Grant
    Filed: January 17, 2018
    Date of Patent: March 17, 2020
    Assignee: PFIZER INC.
    Inventors: Debra D. Pittman, Rodney M. Camire, Joachim Fruebis
  • Compositions and methods for enhancing coagulation factor VIII function
    Patent number: 10442850
    Abstract: Factor VIII variants and methods of use thereof are disclosed.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: October 15, 2019
    Assignee: The Children's Hospital of Philadelphia
    Inventors: Valder Arruda, Rodney M. Camire, Nicholas Iacobelli
  • Compositions and methods for modulating thrombin generation
    Patent number: 10239933
    Abstract: Factor V peptides and methods of use thereof are disclosed.
    Type: Grant
    Filed: April 18, 2016
    Date of Patent: March 26, 2019
    Assignee: The Children's Hospital of Philadelphia
    Inventors: Rodney M. Camire, Matthew W. Bunce, Mettine H. A. Bos
  • Compositions and Methods for Modulating Factor IX Function
    Publication number: 20190024071
    Abstract: Factor IX/IXa variants and methods of use thereof are disclosed.
    Type: Application
    Filed: August 19, 2015
    Publication date: January 24, 2019
    Inventors: Rodney M. Camire, Lacramioara Ivanciu, Valder R. Arruda
  • COMPOSITIONS AND METHODS FOR COUNTERACTING FACTOR XA INHIBITION
    Publication number: 20180344819
    Abstract: The disclosure provides compositions and methods for counteracting the effects of direct activated Factor X (FXa) inhibitors in a subject by administering a variant of FXa.
    Type: Application
    Filed: January 17, 2018
    Publication date: December 6, 2018
    Inventors: Debra D. Pittman, Rodney M. Camire, Joachim Fruebis
  • Compositions and methods for modulating hemostasis
    Patent number: 10106786
    Abstract: Factor X/Xa variants and methods of use thereof are disclosed.
    Type: Grant
    Filed: June 3, 2016
    Date of Patent: October 23, 2018
    Assignee: The Children's Hospital of Philadelphia
    Inventor: Rodney M. Camire
  • Compositions and Methods for Modulating Hemostasis
    Publication number: 20180251745
    Abstract: Factor Xa variants and methods of use thereof are disclosed.
    Type: Application
    Filed: February 20, 2018
    Publication date: September 6, 2018
    Inventor: Rodney M. Camire
  • Compositions and methods for modulating hemostasis
    Patent number: 9896676
    Abstract: Factor Xa variants and methods of use thereof are disclosed.
    Type: Grant
    Filed: August 5, 2016
    Date of Patent: February 20, 2018
    Assignee: THE CHILDREN'S HOSPITAL OF PHILADELPHIA
    Inventor: Rodney M. Camire
  • COMPOSITIONS AND METHODS FOR ENHANCING COAGULATION FACTOR VIII FUNCTION
    Publication number: 20170369554
    Abstract: Factor VIII variants and methods of use thereof are disclosed.
    Type: Application
    Filed: June 5, 2017
    Publication date: December 28, 2017
    Applicant: The Children's Hospital of Philadelphia
    Inventors: Valder ARRUDA, Rodney M. CAMIRE, Nicholas IACOBELLI
  • Compositions and Methods for Modulating Hemostasis
    Publication number: 20170247677
    Abstract: Factor X/Xa variants and methods of use thereof are disclosed.
    Type: Application
    Filed: June 3, 2016
    Publication date: August 31, 2017
    Inventor: Rodney M. Camire
  • Compositions and Methods for Modulating Hemostasis
    Publication number: 20160362673
    Abstract: Factor Xa variants and methods of use thereof are disclosed.
    Type: Application
    Filed: August 5, 2016
    Publication date: December 15, 2016
    Inventor: Rodney M. Camire
  • Compositions and Methods for Increasing the Half-Life of Factor XA
    Publication number: 20160235824
    Abstract: Compositions and methods for the modulation of hemostasis are disclosed.
    Type: Application
    Filed: November 3, 2014
    Publication date: August 18, 2016
    Applicant: The Children's Hospital Philadelphia
    Inventors: Rodney M Camire, Nabil K. Thalji
  • Compositions and methods for modulating hemostasis
    Patent number: 9410137
    Abstract: Factor Xa variants and methods of use thereof are disclosed.
    Type: Grant
    Filed: December 23, 2012
    Date of Patent: August 9, 2016
    Assignee: The Children's Hospital of Philadelphia
    Inventor: Rodney M. Camire
  • COMPOSITIONS AND METHODS FOR MODULATING THROMBIN GENERATION
    Publication number: 20160222085
    Abstract: Factor V peptides and methods of use thereof are disclosed.
    Type: Application
    Filed: April 18, 2016
    Publication date: August 4, 2016
    Inventors: Rodney M. Camire, Matthew W. Bunce, Mettine H.A. Bos