Abstract: A chromatography column adapted to be used in high performance liquid chromatography which includes an elongated tubular hollow column of rigid material which is enclosed by an outer tubular sleeve. End fittings are removably attachable to opposite ends of the outer tubular sleeve and have longitudinal passageways extending through their length, said passageways terminating in an enlarged bore at their innermost ends wherein ring means are insertable. Opposite ends of the column are also insertable into the enlarged bores of the end fittings. The end fittings are adjustably securable to opposite ends of the sleeve so that opposite ends of the column are brought into secure and sealing abutment with the ring means which in turn are sandwiched against the end fittings.