Patents by Inventor Rodney W. Salo

Rodney W. Salo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160256694
    Abstract: Systems and methods for rate-adaptive pacing are disclosed. In one illustrative embodiment, a medical device for delivering electrical stimulation to a heart may include a housing configured to be implanted on the heart or within a chamber of the heart, one or more electrodes connected to the housing, and a controller disposed within the housing. The controller may be configured to sense a first signal and determine a respiration rate based at least in part on the sensed first signal. In at least some embodiments, the controller may be further configured to adjust a rate of delivery of electrical stimulation by the medical device based at least in part on the determined respiration rate.
    Type: Application
    Filed: March 2, 2016
    Publication date: September 8, 2016
    Inventors: Allan C. Shuros, Rodney W. Salo, Michael J. Kane, Donald L. Hopper
  • Patent number: 9168382
    Abstract: A cardiac rhythm management system provides for cardiac pacing that is delivered to a target portion of conductive tissue in a heart, such as the His bundle. In various embodiments, the system is configured to verify capture of the target portion and provide for selective pacing of the target portion. In various embodiments, the system is configured to detect responses of the target portion and adjacent myocardial tissue to delivery of pacing pulses and use an outcome of the detection to verify selective capture of the target portion (i.e., without directly exciting the adjacent myocardial tissue.
    Type: Grant
    Filed: October 1, 2013
    Date of Patent: October 27, 2015
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Allan C. Shuros, Jiang Ding, Barun Maskara, Rodney W. Salo
  • Publication number: 20150224348
    Abstract: Various aspects relate to a device. Various device embodiments include at least a first and a second transducer, and a controller. The first transducer is adapted to be positioned to direct a first energy wave toward a neural target, and the second transducer is adapted to be positioned to direct a second energy wave toward the neural target. The controller is connected to the transducers to generate the first energy wave with a first predetermined phase and a first predetermined amplitude from the first transducer and to generate the second energy wave with a second predetermined phase and a second predetermined amplitude from the second transducer. The amplitudes are selected so that a neural stimulation threshold is reached only during constructive wave interference. The phases are selected so that the first and second energy waves constructively interfere at the neural target. Other aspects and embodiments are provided herein.
    Type: Application
    Filed: April 23, 2015
    Publication date: August 13, 2015
    Inventors: Anand Iyer, Rodney W. Salo, Anthony V. Caparso, Paul A. Haefner
  • Patent number: 9002452
    Abstract: Pacing pulses are delivered to one or more cardiac regions to improve diastolic performance in patients having diastolic dysfunction and/or heart failure. A cardiac pacing system executes a pacing algorithm using a parameter indicative of the diastolic performance as an input. The pacing pulses excite the one or more cardiac regions to redistribute the loading on the ventricular wall during diastole, thereby improving the diastolic performance by lowering the degree of cardiac wall motion dyssynchrony associated with diastolic dysfunction.
    Type: Grant
    Filed: November 7, 2003
    Date of Patent: April 7, 2015
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Rodney W. Salo, Matthew Salo
  • Patent number: 8831724
    Abstract: A cardiac rhythm management system modulates the delivery of pacing and/or autonomic neurostimulation pulses based on heart rate variability (HRV). An HRV parameter being a measure of the HRV is produced to indicate a patient's cardiac condition, based on which the delivery of pacing and/or autonomic neurostimulation pulses is started, stopped, adjusted, or optimized. In one embodiment, the HRV parameter is used as a safety check to stop an electrical therapy when it is believed to be potentially harmful to continue the therapy.
    Type: Grant
    Filed: January 26, 2010
    Date of Patent: September 9, 2014
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Joseph M. Pastore, Rodney W. Salo, Gerrard M. Carlson, Andrew P. Kramer, Jiang Ding, Yinghong Yu
  • Patent number: 8805503
    Abstract: A cardiac rhythm management system modulates the delivery of pacing and/or autonomic neurostimulation pulses based on heart rate variability (HRV). An HRV parameter being a measure of the HRV is produced to indicate a patient's cardiac condition, based on which the delivery of pacing and/or autonomic neurostimulation pulses is started, stopped, adjusted, or optimized. In one embodiment, the HRV parameter is used to evaluate a plurality of parameter values for selecting an approximately optimal parameter value.
    Type: Grant
    Filed: February 3, 2010
    Date of Patent: August 12, 2014
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Joseph M. Pastore, Rodney W. Salo, Gerrard M. Carlson, Andrew P. Kramer, Jiang Ding, Yinghong Yu
  • Patent number: 8798747
    Abstract: A cardiac rhythm management (CRM) system includes a non-invasive hemodynamic sensing device and an implantable medical device to sense a hemodynamic signal and derive one or more cardiac performance parameters from the hemodynamic signal. The non-invasive hemodynamic sensing device includes at least a portion configured for external attachment to a body in which the implantable medical device is implanted. The one or more cardiac performance parameters are used for various diagnostic, monitoring, and therapy control purposes.
    Type: Grant
    Filed: October 13, 2011
    Date of Patent: August 5, 2014
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Andrew P. Kramer, Joseph M. Pastore, Jeffrey E. Stahmann, Rodney W. Salo, Jesse W. Hartley
  • Patent number: 8731677
    Abstract: Various system embodiments comprise a neural stimulator, a pulse generator, and a controller. The neural stimulator is adapted to generate a neural stimulation signal. The pulse generator is adapted to generate a pacing signal to provide myocardium pacing. The controller is adapted to control the neural stimulator and the pulse generator to provide a cardioprotective conditioning therapy. The conditioning therapy includes neural stimulation to elicit a parasympathetic response and myocardium pacing. Other aspects and embodiments are provided herein.
    Type: Grant
    Filed: February 10, 2010
    Date of Patent: May 20, 2014
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Joseph M. Pastore, Tamara Colette Baynham, Andrew P. Kramer, Julio C. Spinelli, Jeffrey Ross, Rodney W. Salo
  • Patent number: 8731666
    Abstract: A method and device for delivering pre-excitation pacing to prevent or reduce cardiac remodeling following a myocardial infarction is described. The pre-excitation pacing is modulated in accordance with an assessment of cardiac function in order to balance the beneficial effects of stress reduction with hemodynamic compromise.
    Type: Grant
    Filed: June 21, 2010
    Date of Patent: May 20, 2014
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Joseph M. Pastore, Rodney W. Salo, Jesse W. Hartley, Andrew P. Kramer, Jeffrey E. Stahmann
  • Publication number: 20140107724
    Abstract: A cardiac rhythm management system provides for cardiac pacing that is delivered to a target portion of conductive tissue in a heart, such as the His bundle. In various embodiments, the system is configured to verify capture of the target portion and provide for selective pacing of the target portion. In various embodiments, the system is configured to detect responses of the target portion and adjacent myocardial tissue to delivery of pacing pulses and use an outcome of the detection to verify selective capture of the target portion (i.e., without directly exciting the adjacent myocardial tissue.
    Type: Application
    Filed: October 1, 2013
    Publication date: April 17, 2014
    Applicant: Cardiac Pacemakers, Inc.
    Inventors: Allan C. Shuros, Jiang Ding, Barun Maskara, Rodney W. Salo
  • Publication number: 20140039312
    Abstract: Techniques are disclosed for pacing site selection. In one example, a method includes using a sensing element such as an ultrasonic transducer, an optical pressure sensor, a MEMS pressure sensor, a SAW pressure sensor, an accelerometer, a gyroscope, or any other suitable sensing element to sense a measure related to a cardiac strain in a heart resulting from contraction and relaxation of myocardium during a cardiac cycle. Based on the sensed strain, an output may be provided for use by a user of the system to select a segment of the heart for lead placement.
    Type: Application
    Filed: July 30, 2013
    Publication date: February 6, 2014
    Applicant: Cardiac Pacemakers, Inc.
    Inventors: Holly E. Rockweiller, Rodney W. Salo, Bruce A. Tockman, Lewis J. Thomas, III, Aaron R. McCabe, Brian D. Soltis, Darrell L. Rankin, Michael S. Arney, Alex J. Sepulveda
  • Patent number: 8634913
    Abstract: An apparatus for reversing ventricular remodeling with electro-stimulatory therapy. A ventricle is paced by delivering one or more stimulatory pulses in a manner such that a stressed region of the myocardium is pre-excited relative to other regions in order to subject the stressed region to a lessened preload and afterload during systole. The unloading of the stressed myocardium over time effects reversal of undesirable ventricular remodeling.
    Type: Grant
    Filed: February 4, 2013
    Date of Patent: January 21, 2014
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Andrew P. Kramer, Rodney W. Salo, Julio C. Spinelli, Bruce H. KenKnight
  • Patent number: 8612001
    Abstract: A cardiac rhythm management device in which pre-excitation pacing is applied to one or more sites in proximity to an infarcted region of the ventricular myocardium. Such pacing servers to either prevent or minimize post-infarct remodeling.
    Type: Grant
    Filed: February 24, 2011
    Date of Patent: December 17, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventor: Rodney W. Salo
  • Patent number: 8594791
    Abstract: Described herein are methods and apparatus for treating hypertension with electrical pre-excitation pacing therapy. Electrical pre-excitation of a hypertrophic region advances the timing of the regional contraction and reduces its contribution to the overall contraction. Such pre-excitation pacing therapy may be beneficial to hypertensive patients with an abnormal distribution of ventricular wall stress/strain.
    Type: Grant
    Filed: October 22, 2012
    Date of Patent: November 26, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Rodney W. Salo, Robert Shipley
  • Patent number: 8560067
    Abstract: A cardiac electro-stimulatory device and method for operating same in which stimulation pulses are distributed among a plurality of electrodes fixed at different sites of the myocardium in order to reduce myocardial hypertrophy brought about by repeated pacing at a single site and/or increase myocardial contractility. In order to spatially and temporally distribute the stimulation, the pulses are delivered through a switchable pulse output configuration during a single cardiac cycle, with each configuration comprising one or more electrodes fixed to different sites in the myocardium.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: October 15, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Rodney W. Salo, Julio C. Spinelli, Bruce H. KenKnight
  • Patent number: 8538520
    Abstract: A gene regulatory system detects ischemia events and is capable of delivering a biologic therapy in response to the detection of an ischemic event or the reception of a command. The biologic therapy protects the heart from ischemic damage by regulating the expression of an exogenously introduced gene product. In one embodiment, the gene regulatory system includes an implantable system that emits at least one gene regulatory signal in response to the detection of the ischemic event or the reception of the command. The gene regulatory signal directly or indirectly regulates gene expression of the gene product.
    Type: Grant
    Filed: July 6, 2010
    Date of Patent: September 17, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Joseph M. Pastore, Jeffrey Ross, Tamara Colette Baynham, Rodney W. Salo, Andrew P. Kramer, Julio C. Spinelli
  • Patent number: 8442639
    Abstract: Disclosed herein, among other things, is a system for electrical stimulation of blood vessels. An embodiment of the system includes at least one electrode having electrical contact with a blood vessel. The embodiment also includes a stimulation circuit electrically connected to the electrode, the circuit adapted to provide stimulation to the vessel. The embodiment further includes a controller connected to the circuit, the controller adapted to select frequency and voltage parameters for the stimulation circuit to selectively affect vascular therapy, including constriction of the vessel and dilation of the vessel. According to various embodiments, the stimulation circuit and controller are contained within an implantable medical device (IMD). The system also includes a sensor connected to the controller, and the controller initiates and adjusts therapy based on a signal received from the sensor, in varying embodiments.
    Type: Grant
    Filed: February 13, 2007
    Date of Patent: May 14, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Joseph Walker, Rodney W. Salo, Anand Iyer, Joseph M. Pastore, Eric Mokelke
  • Patent number: 8412324
    Abstract: A method and device for treating myocardial ischemia are described in which the stress experienced by a myocardial region identified as vulnerable to becoming ischemic is varied with pre-excitation pacing. In an unloading mode, pacing is applied in proximity to the vulnerable region to reduce stress and the metabolic demand of the region. In a loading mode, pacing is applied to a region remote from the vulnerable region in order to produce a conditioning effect.
    Type: Grant
    Filed: May 9, 2011
    Date of Patent: April 2, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Rodney W. Salo, Allan C. Shuros, Tamara Colette Baynham
  • Patent number: 8406878
    Abstract: A method for treating patients after a myocardial infarction which includes pacing therapy is disclosed. A cardiac rhythm management device is configured to deliver pre-excitation pacing to one or more sites in proximity to an infarcted region of the ventricular myocardium. Such pacing acts to minimize the remodeling process to which the heart is especially vulnerable immediately after a myocardial infarction.
    Type: Grant
    Filed: October 25, 2011
    Date of Patent: March 26, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Qingsheng Zhu, Joseph M. Pastore, Rodney W. Salo
  • Patent number: 8369948
    Abstract: An apparatus for reversing ventricular remodeling with electro-stimulatory therapy. A ventricle is paced by delivering one or more stimulatory pulses in a manner such that a stressed region of the myocardium is pre-excited relative to other regions in order to subject the stressed region to a lessened preload and afterload during systole. The unloading of the stressed myocardium over time effects reversal of undesirable ventricular remodeling.
    Type: Grant
    Filed: October 24, 2011
    Date of Patent: February 5, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Andrew P. Kramer, Rodney W. Salo, Julio C. Spinelli, Bruce H. KenKnight