Patents by Inventor Rodolfo Paoletti

Rodolfo Paoletti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymers containing prostaglandin radicals, process for their preparation and use thereof
    Patent number: 4228152
    Abstract: There are disclosed non-toxic polymers having a molecular weight between 1,000 and 1,500,000 and containing prostaglandin radicals directly connected or connected through an oxyalkylenic, aminoalkylenic, or oxyaminoalkylenic chain to a polyacrylic or polymethacrylic backbone. Upon entry of the polymer into the body, the prostaglandin radicals are hydrolyzed causing free prostaglandins to be released in the body. Methods for making the non-toxic polymers and therapeutic compositions containing the non-toxic polymers are also disclosed.
    Type: Grant
    Filed: November 14, 1978
    Date of Patent: October 14, 1980
    Inventors: Paolo Ferruti, Rodolfo Paoletti
  • Therapeutic compositions containing polymers having polyunsaturated acid radicals
    Patent number: 4223011
    Abstract: A polymer having a molecular weight between 1,000 and 1,500,000 characterized in that it contains the radical of a polyunsaturated acid selected from the group consisting of 8,11,14-eicosatrienic acid, 5,8,11,14-eicosatetraenoic acid, and 5,8,11,14,17-eicosapentenoic acid, bound to a macromolecular backbone of polyacrylic or polymethacrylic units through oxyalkylenic, aminoalkylenic or oxyaminoalkylenic chains.
    Type: Grant
    Filed: March 9, 1979
    Date of Patent: September 16, 1980
    Inventors: Paolo Ferruti, Rodolfo Paoletti
  • Novel prostaglandin precursors in polymeric form
    Patent number: 4211865
    Abstract: A novel polymer consisting of a macromolecular polysaccharide matrix which is esterified in whole or in part by activated polyunsaturated acids containing twenty carbon atoms. Typical of these acids are, for example, 8, 11, 14-eicosatrienoic acid, 5, 8, 11, 14-eicosatetraenoic acid and 5, 8, 11, 14, 17-eicosapentenoic acid. These polymers are therapeutically useful products which have utility in the same fields of application as the prostaglandins but absent their adverse side effects.
    Type: Grant
    Filed: August 10, 1977
    Date of Patent: July 8, 1980
    Inventors: Paolo Ferruti, Rodolfo Paoletti
  • High polymers containing nicotinic acid, process for their preparation and their use
    Patent number: 4169923
    Abstract: Polymers having molecular weight between 1,000 and 1,500,000 characterized in that they contain radicals of nicotinic acid bound to the macromolecular structure by covalent bonds that are gradually hydrolyzed in biological environment by setting free nicotinic acid and non-toxic polymer residues.
    Type: Grant
    Filed: October 27, 1977
    Date of Patent: October 2, 1979
    Inventors: Paolo Ferruti, Rodolfo Paoletti
  • High polymers containing nicotinic acid, process for their preparation and their use
    Patent number: 4166902
    Abstract: New polymers consisting of a macromolecular structure of soluble starch to which 15-30% of nicotinic acid radicals are bound through covalent ester bonds. These polymers are gradually hydrolized in biological environment by setting free nicotinic acid and non toxic polysaccharide residues. These polymers have a therapeutic activity similar to that of nicotinic acid, but by far more long lasting and devoid of collateral effects.
    Type: Grant
    Filed: January 9, 1978
    Date of Patent: September 4, 1979
    Inventors: Paolo Ferruti, Rodolfo Paoletti
  • Polymers containing polyunsaturated acid radicals, process for their preparation and use thereof
    Patent number: 4145320
    Abstract: A polymer having a molecular weight between 1,000 and 1,500,000 characterized in that it contains the radical of a polyunsaturated acid selected from the group consisting of 8, 11, 14-eicosatrienic acid, 5, 8, 11, 14-eicosatetraenoic acid, and 5, 8, 11, 14, 17-eicosapentenoic acid, bound to a macromolecular backbone of polyacrylic or polymethacrylic units through oxyalkylenic, aminoalkylenic or oxyaminoalkylenic chains.
    Type: Grant
    Filed: November 1, 1976
    Date of Patent: March 20, 1979
    Inventors: Paolo Ferruti, Rodolfo Paoletti
  • High polymers containing nicotinic acid, process for their preparation and their use
    Patent number: 4067876
    Abstract: Polymers having molecular weight between 1,000 and 1,500,000 characterized in that they contain radicals of nicotinic acid bound to the macromolecular structure by covalent bonds that are gradually hydrolyzed in biological environment by setting free nicotinic acid and non-toxic polymer residues.
    Type: Grant
    Filed: October 14, 1975
    Date of Patent: January 10, 1978
    Inventors: Paolo Ferruti, Rodolfo Paoletti