Patents by Inventor Rodolphe Barrangou

Rodolphe Barrangou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110008292
    Abstract: Fructooligosaccharide (FOS)-related protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, FOS-related fusion proteins, antigenic peptides, and anti-FOS-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides of the invention and methods for their use are further disclosed.
    Type: Application
    Filed: September 23, 2010
    Publication date: January 13, 2011
    Applicant: North Carolina State University
    Inventors: Rodolphe Barrangou, Todd R. Klaenhammer, Eric Altermann
  • Publication number: 20110002889
    Abstract: The present invention provides methods and compositions related to modulating the resistance of a cell against a target nucleic acid or a transcription product thereof. In some preferred embodiments, the present invention provides compositions and methods for the use of one or more cas genes or proteins for modulating the resistance of a cell against a target nucleic acid or a transcription product thereof. In some embodiments, the present invention provides methods and compositions that find use in the development and use of strain combinations and starter culture rotations. In additional embodiments, the present invention provides methods for labelling and/or identifying bacteria. In some preferred embodiments, the present invention provides methods for the use of CRISPR loci to determine the potential virulence of a phage against a cell and the use of CRISPR-cas to modulate the genetic sequence of a phage for increased virulence level.
    Type: Application
    Filed: February 29, 2008
    Publication date: January 6, 2011
    Inventors: Rodolphe Barrangou, Christophe Fremaux, Philippe Horvath, Dennis Romero, Patrick Boyaval
  • Patent number: 7838276
    Abstract: Carbohydrate utilization-related and multidrug transporter nucleic acids and polypeptides, and fragments and variants thereof, are disclosed in the current invention. In addition, carbohydrate utilization-related and multidrug transporter fusion proteins, antigenic peptides, and anti-carbohydrate utilization-related and anti-multidrug transporter antibodies are encompassed. The invention also provides vectors containing a nucleic acid of the invention and cells into which the vector has been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Grant
    Filed: October 22, 2008
    Date of Patent: November 23, 2010
    Assignee: North Carolina State University
    Inventors: Todd R. Klaenhammer, Eric R. Altermann, Rodolphe Barrangou, W. Michael Russell, Tri Duong
  • Patent number: 7824894
    Abstract: Fructooligosaccharide (FOS)-related protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, FOS-related fusion proteins, antigenic peptides, and anti-FOS-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides of the invention and methods for their use are further disclosed.
    Type: Grant
    Filed: July 2, 2008
    Date of Patent: November 2, 2010
    Assignee: North Carolina State University
    Inventors: Rodolphe Barrangou, Todd R. Klaenhammer, Eric Altermann
  • Publication number: 20100104690
    Abstract: The present invention provides methods for tagging and/or identifying microorganisms. In some preferred embodiments, the microorganisms are bacteria. In some particularly preferred embodiments, the bacteria are members of the genus Streptococcus, while in other embodiments, the bacteria are members of other genera. The present invention also provides microorganisms tagged using the methods set forth herein. In some preferred embodiments, the tagged microorganisms are bacteria. In some particularly preferred embodiments, the tagged bacteria are members of the genus Streptococcus, while in other embodiments, the tagged bacteria are members of other genera.
    Type: Application
    Filed: May 18, 2007
    Publication date: April 29, 2010
    Inventors: Rodolphe Barrangou, Christophe Fremaux, Philippe Horvath
  • Use
    Publication number: 20100093617
    Abstract: The present invention relates to the use of one or more cas genes for modulating resistance in a cell against a target nucleic acid or a transcription product thereof.
    Type: Application
    Filed: August 25, 2006
    Publication date: April 15, 2010
    Inventors: Rodolphe Barrangou, Patrick Boyaval, Christophe Fremaux, Philippe Horvath, Dennis Romero
  • Publication number: 20090155913
    Abstract: Nucleic acid molecules, fragments and variants thereof having promoter activity are provided in the current invention. The invention also provides vectors containing a nucleic acid molecule of the invention and cells comprising the vectors. Methods for making and using the nucleic acid molecules of the invention are further provided.
    Type: Application
    Filed: October 29, 2008
    Publication date: June 18, 2009
    Applicant: North Carolina State University
    Inventors: Rodolphe Barrangou, Andrea Azcarate-Peril, Eric Altermann, Tri Duong, Todd R. Klaenhammer
  • Publication number: 20090093021
    Abstract: Carbohydrate utilization-related and multidrug transporter nucleic acids and polypeptides, and fragments and variants thereof, are disclosed in the current invention. In addition, carbohydrate utilization-related and multidrug transporter fusion proteins, antigenic peptides, and anti-carbohydrate utilization-related and anti-multidrug transporter antibodies are encompassed. The invention also provides vectors containing a nucleic acid of the invention and cells into which the vector has been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Application
    Filed: October 22, 2008
    Publication date: April 9, 2009
    Applicant: North Carolina State University
    Inventors: Todd R. Klaenhammer, Eric Altermann, Rodolphe Barrangou, W. Michael Russell, Tri Duong
  • Patent number: 7495092
    Abstract: Nucleic acid molecules, fragments and variants thereof having promoter activity are provided in the current invention. The invention also provides vectors containing a nucleic acid molecule of the invention and cells comprising the vectors. Methods for making and using the nucleic acid molecules of the invention are further provided.
    Type: Grant
    Filed: January 12, 2006
    Date of Patent: February 24, 2009
    Assignee: North Carolina State University
    Inventors: Rodolphe Barrangou, Andrea Azcarate-Peril, Eric Altermann, Tri Duong, Todd R. Klaenhammer
  • Publication number: 20090005311
    Abstract: Fructooligosaccharide (FOS)-related protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, FOS-related fusion proteins, antigenic peptides, and anti-FOS-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides of the invention and methods for their use are further disclosed.
    Type: Application
    Filed: July 2, 2008
    Publication date: January 1, 2009
    Applicant: North Carolina State University
    Inventors: Rodolphe Barrangou, Todd R. Klaenhammer, Eric Altermann
  • Patent number: 7459289
    Abstract: Carbohydrate utilization-related and multidrug transporter nucleic acids and polypeptides, and fragments and variants thereof, are disclosed in the current invention. In addition, carbohydrate utilization-related and multidrug transporter fusion proteins, antigenic peptides, and anti-carbohydrate utilization-related and anti-multidrug transporter antibodies are encompassed. The invention also provides vectors containing a nucleic acid of the invention and cells into which the vector has been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Grant
    Filed: March 7, 2005
    Date of Patent: December 2, 2008
    Assignee: North Carolina State University
    Inventors: Todd R. Klaenhammer, Eric Altermann, Rodolphe Barrangou, W. Michael Russell, Tri Duong
  • Patent number: 7407787
    Abstract: Fructooligosaccharide (FOS)-related protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, FOS-related fusion proteins, antigenic peptides, and anti-FOS-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides of the invention and methods for their use are further disclosed.
    Type: Grant
    Filed: June 22, 2004
    Date of Patent: August 5, 2008
    Assignee: North Carolina State University
    Inventors: Rodolphe Barrangou, Todd R. Klaenhammer, Eric Altermann
  • Publication number: 20080124725
    Abstract: The present invention provides methods for tagging and/or identifying microorganisms. In some preferred embodiments, the microorganisms are bacteria. In some particularly preferred embodiments, the bacteria are members of the genus Streptococcus, while in other embodiments, the bacteria are members of other genera. The present invention also provides microorganisms tagged using the methods set forth herein. In some preferred embodiments, the tagged microorganisms are bacteria. In some particularly preferred embodiments, the tagged bacteria are members of the genus Streptococcus, while in other embodiments, the tagged bacteria are members of other genera.
    Type: Application
    Filed: May 18, 2007
    Publication date: May 29, 2008
    Inventors: Rodolphe Barrangou, Christophe Fremaux, Philippe Horvath, Dennis Romero
  • Publication number: 20070003668
    Abstract: Carbohydrate utilization-related and multidrug transporter nucleic acids and polypeptides, and fragments and variants thereof, are disclosed in the current invention. In addition, carbohydrate utilization-related and multidrug transporter fusion proteins, antigenic peptides, and anti-carbohydrate utilization-related and anti-multidrug transporter antibodies are encompassed. The invention also provides vectors containing a nucleic acid of the invention and cells into which the vector has been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Application
    Filed: March 7, 2005
    Publication date: January 4, 2007
    Inventors: Todd Klaenhammer, Eric Altermann, Rodolphe Barrangou, W. Russell, Tri Duong
  • Publication number: 20060199190
    Abstract: Methods for the detection and typing of bacterial strains from food products and dietary supplements, environmental samples, in vivo/in vitro samples, and for studying the natural diversity of the species are disclosed. Potential applications also include product development and/or detection and differentiation of new bacterial strains.
    Type: Application
    Filed: April 27, 2005
    Publication date: September 7, 2006
    Applicant: Danisco A/S
    Inventors: W. Russell, Rodolphe Barrangou, Philippe Horvath
  • Publication number: 20060166323
    Abstract: Nucleic acid molecules, fragments and variants thereof having promoter activity are provided in the current invention. The invention also provides vectors containing a nucleic acid molecule of the invention and cells comprising the vectors. Methods for making and using the nucleic acid molecules of the invention are further provided.
    Type: Application
    Filed: January 12, 2006
    Publication date: July 27, 2006
    Applicant: North Carolina State University
    Inventors: Rodolphe Barrangou, Andrea Azcarate-Peril, Eric Altermann, Tri Duong, Todd Klaenhammer
  • Publication number: 20050123941
    Abstract: Fructooligosaccharide (FOS)-related protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, FOS-related fusion proteins, antigenic peptides, and anti-FOS-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides of the invention and methods for their use are further disclosed.
    Type: Application
    Filed: June 22, 2004
    Publication date: June 9, 2005
    Inventors: Rodolphe Barrangou, Todd Klaenhammer, Eric Altermann