Patents by Inventor Rodrigo Aparecido FERNANDES REDONDO

Rodrigo Aparecido FERNANDES REDONDO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR SYNTHESIS OF POLYNUCLEOTIDES USING A DIVERSE LIBRARY OF OLIGONUCLEOTIDES
    Publication number: 20220348902
    Abstract: A method for synthesizing a target double stranded (ds) polynucleotide byproviding an oligonucleotide library within an array device that has a diversity of oligonucleotide library members, each of which has a different nucleotide sequence and is contained in a separate library containment in an aqueous solution. The library includes single stranded oligonucleotides and double stranded oligonucleotides with at least one overhang and covers at least 10,000 pairs of matching oligonucleotides. In a first step, at least a first pair of matching oligonucleotides are transferred transferred from the library into a first reaction containment using a liquid handler and the matching oligonucleotides are assembled, thereby obtaining a first reaction product comprising at least one overhang.
    Type: Application
    Filed: May 18, 2022
    Publication date: November 3, 2022
    Inventors: Harold Paul VLADAR, Rodrigo Aparecido FERNANDES REDONDO
  • Method for synthesis of polynucleotides using a diverse library of oligonucleotides
    Patent number: 11352619
    Abstract: A method for synthesizing a target double stranded (ds) polynucleotide by providing an oligonucleotide library within an array device that has a diversity of oligonucleotide library members, each of which has a different nucleotide sequence and is contained in a separate library containment in an aqueous solution. The library includes single stranded oligonucleotides and double stranded oligonucleotides with at least one overhang and covers at least 10,000 pairs of matching oligonucleotides. In a first step, transferring at least a first pair of matching oligonucleotides transferred from the library into a first reaction containment using a liquid handler and the matching oligonucleotides are assembled, thereby obtaining a first reaction product comprising at least one overhang.
    Type: Grant
    Filed: October 15, 2018
    Date of Patent: June 7, 2022
    Assignee: RIBBON BIOLABS GMBH
    Inventors: Harold Paul Vladar, Rodrigo Aparecido Fernandes Redondo
  • A NOVEL METHOD FOR SYNTHESIS OF POLYNUCLEOTIDES USING A DIVERSE LIBRARY OF OLIGONUCLEOTIDES
    Publication number: 20200283756
    Abstract: A method for synthesizing a target double stranded (ds) polynucleotide having a predefined sequence, comprising a) providing an oligonucleotide library within an array device, which comprises a diversity of oligonucleotide library members, wherein each of the library members has a different nucleotide sequence and is contained in a separate library containment in an aqueous solution, which diversity includes single stranded oligonucleotides (ss oligos) and double stranded oligonucleotides (ds oligos) with at least one overhang and covers at least 10.
    Type: Application
    Filed: October 15, 2018
    Publication date: September 10, 2020
    Inventors: Harold Paul VLADAR, Rodrigo Aparecido FERNANDES REDONDO